This is a Validated Antibody Database (VAD) review about human EIF4G1, based on 28 published articles (read how Labome selects the articles), using EIF4G1 antibody in all methods. It is aimed to help Labome visitors find the most suited EIF4G1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EIF4G1 synonym: EIF-4G1; EIF4F; EIF4G; EIF4GI; P220; PARK18

Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology EIF4G1 antibody (Santa Cruz Biotechnology, sc-133155) was used in western blot on human samples (fig 2b). Cancer Res (2019) ncbi
mouse monoclonal (A-10)
  • western blot; human; 1:1000; loading ...; fig 4d
Santa Cruz Biotechnology EIF4G1 antibody (Santa Cruz, sc-133155) was used in western blot on human samples at 1:1000 (fig 4d). Nat Commun (2017) ncbi
mouse monoclonal (A-10)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology EIF4G1 antibody (SantaCruz, sc-133155) was used in immunohistochemistry - paraffin section on human samples (fig 1) and in western blot on human samples (fig 2a). Exp Neurol (2018) ncbi
mouse monoclonal (H-2)
  • western blot; human; 1:500; fig 8
Santa Cruz Biotechnology EIF4G1 antibody (Santa Cruz, sc-373892) was used in western blot on human samples at 1:500 (fig 8). BMC Mol Biol (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:500; fig 3
Abcam EIF4G1 antibody (Abcam, ab2609) was used in western blot on human samples at 1:500 (fig 3). Nat Commun (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C45A4)
  • RNA immunoprecipitation; human; loading ...; fig s3d
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469) was used in RNA immunoprecipitation on human samples (fig s3d). Commun Biol (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; fig 1d
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technology, 2498) was used in western blot on human samples at 1:2000 (fig 1d). Cell Syst (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s1c
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2498) was used in western blot on mouse samples at 1:1000 (fig s1c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (C45A4)
  • western blot; mouse; 1:1000; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig 2b, 8a
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469) was used in western blot on mouse samples at 1:1000 (fig 3a) and in western blot on human samples at 1:1000 (fig 2b, 8a). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 7c
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technologies, 2858) was used in western blot on human samples (fig 7c). J Virol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1b
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2498) was used in western blot on human samples at 1:1000 (fig 1b). Int J Biol Sci (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1b
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technology, 2498) was used in immunohistochemistry on mouse samples (fig 1b). Eur J Immunol (2019) ncbi
domestic rabbit monoclonal (D6A6)
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, D6A6) was used in western blot on human samples at 1:1000 (fig 1a). Proc Natl Acad Sci U S A (2019) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2498) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (C45A4)
  • immunohistochemistry; human; loading ...; fig 3c
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469S) was used in immunohistochemistry on human samples (fig 3c) and in western blot on human samples (fig 2a). PLoS Pathog (2018) ncbi
domestic rabbit monoclonal (D6A6)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1c
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3b
  • western blot; mouse; 1:3000; loading ...; fig 1b
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 8701S) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1c), in immunocytochemistry on mouse samples at 1:100 (fig 3b) and in western blot on mouse samples at 1:3000 (fig 1b). Biol Reprod (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technology, 2858) was used in western blot on mouse samples (fig 3f). Cancer Res (2017) ncbi
domestic rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, C45A4) was used in western blot on mouse samples (fig 3b). Cell Death Differ (2017) ncbi
domestic rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology EIF4G1 antibody (CST, 2498) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig s1a
In order to study the role of Yin-yang 2 in mouse embryonic stem cells, Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469) was used in western blot on mouse samples (fig s1a). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig s3d
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469) was used in western blot on mouse samples (fig s3d). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
In order to identify a cap-dependent translation mechanism that is independent of eIF4E, Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2858) was used in western blot on human samples (fig 1b). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; fruit fly ; fig s1
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2498) was used in western blot on fruit fly samples (fig s1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2498) was used in western blot on human samples (fig 4d). Mol Cell (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 7
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technology, 2498) was used in western blot on human samples (fig 7). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology EIF4G1 antibody (Cell Signaling Technologies, 2858) was used in western blot on human samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2441S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C45A4)
  • western blot; human; fig 4
Cell Signaling Technology EIF4G1 antibody (Cell Signaling, 2469S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
MBL International
  • RNA immunoprecipitation; human
  • immunocytochemistry; human; 2 ug/ml
  • western blot; human; 0.5 ug/ml
In order to develop reagents to study RNA binding proteins, MBL International EIF4G1 antibody (MBLI, RN002P) was used in RNA immunoprecipitation on human samples , in immunocytochemistry on human samples at 2 ug/ml and in western blot on human samples at 0.5 ug/ml. Mol Cell (2016) ncbi
Articles Reviewed
  1. Turco C, Esposito G, Iaiza A, Goeman F, Benedetti A, Gallo E, et al. MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer. Commun Biol. 2022;5:598 pubmed publisher
  2. Lopacinski A, Sweatt A, Smolko C, Gray Gaillard E, Borgman C, Shah M, et al. Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Syst. 2021;12:304-323.e13 pubmed publisher
  3. Xu Z, Kim G, Tan J, Riso A, Sun Y, Xu E, et al. Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations. Nat Commun. 2020;11:1797 pubmed publisher
  4. Mosaheb M, Dobrikova E, Brown M, Yang Y, Cable J, Okada H, et al. Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity. Nat Commun. 2020;11:524 pubmed publisher
  5. Pringle E, Robinson C, McCormick C. Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis. J Virol. 2019;93: pubmed publisher
  6. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  7. William M, Leroux L, Chaparro V, Graber T, Alain T, Jaramillo M. Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells. Eur J Immunol. 2019;49:1200-1212 pubmed publisher
  8. Li X, Zhu Q, Shi X, Cheng Y, Li X, Xu H, et al. O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis. Proc Natl Acad Sci U S A. 2019;116:7857-7866 pubmed publisher
  9. Wang Z, Feng X, Molinolo A, Martin D, Vitale Cross L, Nohata N, et al. 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer. Cancer Res. 2019;: pubmed publisher
  10. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  11. Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, et al. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathog. 2018;14:e1006901 pubmed publisher
  12. Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
  13. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  14. Hsu J, Hubbell Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al. PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Res. 2017;77:4613-4625 pubmed publisher
  15. Lingel H, Wissing J, Arra A, Schanze D, Lienenklaus S, Klawonn F, et al. CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation. Cell Death Differ. 2017;24:1739-1749 pubmed publisher
  16. Oblinger J, Burns S, Huang J, Pan L, Ren Y, Shen R, et al. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 2018;299:299-307 pubmed publisher
  17. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  18. Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
  19. Frydryskova K, Masek T, Borcin K, Mrvova S, Venturi V, Pospisek M. Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules. BMC Mol Biol. 2016;17:21 pubmed publisher
  20. Tsai S, Rodriguez A, Dastidar S, Del Greco E, Carr K, Sitzmann J, et al. Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice. Cell Rep. 2016;16:1903-14 pubmed publisher
  21. Lee A, Kranzusch P, Doudna J, Cate J. eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature. 2016;536:96-9 pubmed
  22. Penney J, Tsurudome K, Liao E, Kauwe G, Gray L, Yanagiya A, et al. LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. Nat Commun. 2016;7:12188 pubmed publisher
  23. Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  24. Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
  25. Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
  26. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  27. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  28. Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher