This is a Validated Antibody Database (VAD) review about human EIF4EBP2, based on 7 published articles (read how Labome selects the articles), using EIF4EBP2 antibody in all methods. It is aimed to help Labome visitors find the most suited EIF4EBP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EIF4EBP2 synonym: 4EBP2; PHASII; eukaryotic translation initiation factor 4E-binding protein 2; 4E-BP2; eIF4E-binding protein 2; phosphorylated, heat and acid stable regulated by insulin protein II

Knockout validation
Cell Signaling Technology
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 1s2
Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling Technology, 2845) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s2). elife (2015) ncbi
Abcam
rabbit monoclonal (EPR2169Y)
  • western blot; human; loading ...; fig 5a
In order to study the synergistic antitumor effect of simultaneously targeting CD47 and autophagy in non-small cell lung cancer, Abcam EIF4EBP2 antibody (Abcam, ab68187) was used in western blot on human samples (fig 5a). Cancer Immunol Res (2017) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; loading ...; fig s2a
In order to study the role of Yin-yang 2 in mouse embryonic stem cells, Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling, 2845) was used in western blot on mouse samples (fig s2a). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1e
In order to propose that PTEN's role in axonal polarity can be independent of PIP3, Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling, 2845) was used in western blot on mouse samples (fig 1e). Biochim Biophys Acta (2016) ncbi
rabbit polyclonal
Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling Technology, 13435) was used . Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; fig 1s2
Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling Technology, 2845) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s2). elife (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
  • immunohistochemistry; human; loading ...; fig 2c
Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling, 2845) was used in western blot on mouse samples (fig 1b) and in immunohistochemistry on human samples (fig 2c). EMBO Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig f6
In order to find a developmental role for LAT3 in red blood cells and report that mTORC1 acts as a homeostatic sensor, Cell Signaling Technology EIF4EBP2 antibody (Cell Signaling Technologies, 2845) was used in western blot on mouse samples (fig f6). Sci Signal (2015) ncbi
Articles Reviewed
  1. Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed publisher
  2. Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
  3. Diez H, Benitez M, Fernandez S, Torres Aleman I, Garrido J, Wandosell F. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation. Biochim Biophys Acta. 2016;1863:2574-2583 pubmed publisher
  4. Tsukumo Y, Alain T, Fonseca B, Nadon R, Sonenberg N. Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3. Nat Commun. 2016;7:11776 pubmed publisher
  5. Khoutorsky A, Bonin R, Sorge R, Gkogkas C, Pawlowski S, Jafarnejad S, et al. Translational control of nociception via 4E-binding protein 1. elife. 2015;4: pubmed publisher
  6. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  7. Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed publisher