This is a Validated Antibody Database (VAD) review about human EHMT1, based on 10 published articles (read how Labome selects the articles), using EHMT1 antibody in all methods. It is aimed to help Labome visitors find the most suited EHMT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
EHMT1 synonym: EHMT1-IT1; EUHMTASE1; Eu-HMTase1; FP13812; GLP; GLP1; KLEFS1; KMT1D; histone-lysine N-methyltransferase EHMT1; EHMT1 intronic transcript 1; G9a-like protein 1; H3-K9-HMTase 5; euchromatic histone-lysine N-methyltransferase 1; histone H3-K9 methyltransferase 5; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; lysine N-methyltransferase 1D

R&D Systems
mouse monoclonal (B0422)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s3c
R&D Systems EHMT1 antibody (R&D, B0422) was used in immunohistochemistry - paraffin section on mouse samples (fig s3c). J Cell Biol (2018) ncbi
mouse monoclonal (B0422)
  • immunocytochemistry; human; 5 ug/ml; fig 4h
R&D Systems EHMT1 antibody (R&D Systems, PP-B0422-00) was used in immunocytochemistry on human samples at 5 ug/ml (fig 4h). Nature (2016) ncbi
mouse monoclonal (B0422)
  • immunohistochemistry; mouse; fig 1
R&D Systems EHMT1 antibody (R&D Systems, PP-B0422-00) was used in immunohistochemistry on mouse samples (fig 1). elife (2015) ncbi
mouse monoclonal (B0422)
  • western blot; rat; 1:1000; fig 2
R&D Systems EHMT1 antibody (R&D Systems, PP-B0422-C00) was used in western blot on rat samples at 1:1000 (fig 2). J Neurosci (2015) ncbi
mouse monoclonal (B0422)
  • western blot; mouse; fig 1
R&D Systems EHMT1 antibody (R&D, B0422) was used in western blot on mouse samples (fig 1). Genes Dev (2014) ncbi
mouse monoclonal (B0422)
  • immunoprecipitation; human
  • western blot; human
R&D Systems EHMT1 antibody (R&D Systems, PP-B0422-00) was used in immunoprecipitation on human samples and in western blot on human samples . Nucleic Acids Res (2012) ncbi
Abcam
mouse monoclonal (B0422)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4a
In order to show that reduced levels of Euchromatin Histone Methyltransferase 1 protein in Ehmt1+/- mice does not result in general learning deficits, but leads to increased adult cell proliferation in the hippocampus and enhanced pattern separation ability, Abcam EHMT1 antibody (Abcam, ab 41969) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 4a). Sci Rep (2017) ncbi
mouse monoclonal (B0422)
  • western blot; mouse; fig s2
Abcam EHMT1 antibody (Abcam, ab41969) was used in western blot on mouse samples (fig s2). Sci Rep (2016) ncbi
mouse monoclonal (B0422)
  • western blot; human; 1:1000; fig 2
Abcam EHMT1 antibody (Abcam, ab41969) was used in western blot on human samples at 1:1000 (fig 2). Blood (2015) ncbi
MBL International
monoclonal (C7-5)
  • western blot; human; 1:1000; loading ...; fig s7
In order to propose that the NKX3.1-G9a-UTY transcriptional regulatory network is essential for prostate differentiation, MBL International EHMT1 antibody (mbl, D220-3) was used in western blot on human samples at 1:1000 (fig s7). Science (2016) ncbi
Articles Reviewed
  1. Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  2. Benevento M, Oomen C, Horner A, Amiri H, Jacobs T, Pauwels C, et al. Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation. Sci Rep. 2017;7:40284 pubmed publisher
  3. Ow J, Palanichamy Kala M, Rao V, Choi M, Bharathy N, Taneja R. G9a inhibits MEF2C activity to control sarcomere assembly. Sci Rep. 2016;6:34163 pubmed publisher
  4. Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science. 2016;352:1576-80 pubmed publisher
  5. Tu S, Narendra V, Yamaji M, Vidal S, Rojas L, Wang X, et al. Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature. 2016;534:387-90 pubmed publisher
  6. Zylicz J, Dietmann S, Günesdogan U, Hackett J, Cougot D, Lee C, et al. Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development. elife. 2015;4: pubmed publisher
  7. Renneville A, van Galen P, Canver M, McConkey M, Krill Burger J, Dorfman D, et al. EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. Blood. 2015;126:1930-9 pubmed publisher
  8. Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 2015;35:352-65 pubmed publisher
  9. Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, et al. The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes Dev. 2014;28:317-27 pubmed publisher
  10. Mund A, Schubert T, Staege H, Kinkley S, Reumann K, Kriegs M, et al. SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Nucleic Acids Res. 2012;40:11363-79 pubmed publisher