This is a Validated Antibody Database (VAD) review about human Dsg1, based on 16 published articles (read how Labome selects the articles), using Dsg1 antibody in all methods. It is aimed to help Labome visitors find the most suited Dsg1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dsg1 synonym: CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1

Invitrogen
mouse monoclonal (27B2)
  • flow cytometry; human; loading ...; fig 2c
In order to study the function of desmoglein-2 and generate knockout mice, Invitrogen Dsg1 antibody (Life Technologies, 27B2) was used in flow cytometry on human samples (fig 2c). Angiogenesis (2016) ncbi
mouse monoclonal (27B2)
  • immunohistochemistry; human
In order to evaluate early dental epithelial transcription factors as a diagnostic marker for ameloblastoma and keratocystic odontogenic tumor, Invitrogen Dsg1 antibody (Invitrogen, 32-6000) was used in immunohistochemistry on human samples . J Dent Res (2015) ncbi
mouse monoclonal (27B2)
  • western blot; human; fig 1
In order to assess if the EphA2/ephrin-A1 signaling axis is altered in psoriasis, Invitrogen Dsg1 antibody (Zymed, 27B2) was used in western blot on human samples (fig 1). J Invest Dermatol (2013) ncbi
mouse monoclonal (27B2)
  • immunohistochemistry; human; 1:10
In order to examine the contribution of the desmosomal compartment to gastroesophageal reflux disease, Invitrogen Dsg1 antibody (Zymed, 326000) was used in immunohistochemistry on human samples at 1:10. Hum Pathol (2012) ncbi
mouse monoclonal (27B2)
  • immunohistochemistry; human; 1:10; fig 1
In order to examine the role of desmosomal proteins in gastro-oesophageal reflux disease, Invitrogen Dsg1 antibody (Zymed, 326000) was used in immunohistochemistry on human samples at 1:10 (fig 1). Histopathology (2012) ncbi
mouse monoclonal (27B2)
  • western blot; human; fig 3
In order to suggest that EphA2-expressing keratinocytes respond to ephrin-A1-based cues from their neighbors to facilitate entry into a terminal differentiation pathway, Invitrogen Dsg1 antibody (Zymed, 27B2) was used in western blot on human samples (fig 3). Mol Biol Cell (2010) ncbi
mouse monoclonal (27B2)
  • immunoprecipitation; human; fig 2
In order to test if p120ctn associates with Dsg1 and Dsg3 in keratinocytes, Invitrogen Dsg1 antibody (Zymed, 27B2) was used in immunoprecipitation on human samples (fig 2). J Dermatol (2008) ncbi
mouse monoclonal (27B2)
  • immunohistochemistry - paraffin section; human; 1:100; tbl 1
In order to develop a living skin-equivalent from de-epithelialized amnion membrane, Invitrogen Dsg1 antibody (Zymed, 27B2) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 1). Cell Tissue Res (2006) ncbi
Abcam
mouse monoclonal (27B2)
  • western blot; human; 1:50; loading ...; fig 2b
Abcam Dsg1 antibody (Abcam, Ab12077) was used in western blot on human samples at 1:50 (fig 2b). Cell Rep (2021) ncbi
mouse monoclonal (27B2)
Abcam Dsg1 antibody (Abcam, 27B2) was used . J Dermatol Sci (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-11)
  • immunohistochemistry - paraffin section; human; 1:50; fig 4e
Santa Cruz Biotechnology Dsg1 antibody (Santa Cruz, sc-137164) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4e). Cell Rep (2021) ncbi
American Research Products
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:50
American Research Products Dsg1 antibody (American Research Products, 03-61002) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. PLoS ONE (2015) ncbi
Bio-Rad
mouse monoclonal (27B2)
  • western blot; human; loading ...; fig 3c
Bio-Rad Dsg1 antibody (Bio-Rad, MCA2271) was used in western blot on human samples (fig 3c). Am J Hum Genet (2016) ncbi
Progen
mouse monoclonal (DG 3.10)
  • immunocytochemistry; mouse; 1:50; fig 3a
  • western blot; mouse; 1:100; fig 3b
In order to discuss the cellular origins of fibroadipocytes in arrhythmogenic cardiomyopathy, Progen Dsg1 antibody (Progen, 61002) was used in immunocytochemistry on mouse samples at 1:50 (fig 3a) and in western blot on mouse samples at 1:100 (fig 3b). Circ Res (2016) ncbi
mouse monoclonal (DG 3.10)
Progen Dsg1 antibody (Progen, 61002) was used . J Biochem (2015) ncbi
Fitzgerald Industries
  • immunohistochemistry - frozen section; domestic sheep
In order to study the role of desmosomes and adherens junctions in gap junction formation by cx43, Fitzgerald Industries Dsg1 antibody (Fitzgerald, 10RD105A) was used in immunohistochemistry - frozen section on domestic sheep samples . Heart Rhythm (2012) ncbi
BD Biosciences
mouse monoclonal (62/Desmoglein)
  • western blot; human; fig 2s2
In order to analyze Src homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases by time-resolved multimodal analysis, BD Biosciences Dsg1 antibody (Becton-Dickinson, 610274) was used in western blot on human samples (fig 2s2). elife (2016) ncbi
Articles Reviewed
  1. Simpson C, Tokito M, Uppala R, Sarkar M, Gudjonsson J, Holzbaur E. NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation. Cell Rep. 2021;34:108689 pubmed publisher
  2. Yoshida K, Ishii K, Shimizu A, Yokouchi M, Amagai M, Shiraishi K, et al. Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering. J Dermatol Sci. 2017;85:197-207 pubmed publisher
  3. Pigors M, Sarig O, Heinz L, Plagnol V, Fischer J, Mohamad J, et al. Loss-of-Function Mutations in SERPINB8 Linked to Exfoliative Ichthyosis with Impaired Mechanical Stability of Intercellular Adhesions. Am J Hum Genet. 2016;99:430-6 pubmed publisher
  4. Ebert L, Tan L, Johan M, Min K, Cockshell M, Parham K, et al. A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis. Angiogenesis. 2016;19:463-86 pubmed publisher
  5. Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
  6. Jadwin J, Oh D, Curran T, Ogiue Ikeda M, Jia L, White F, et al. Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. elife. 2016;5:e11835 pubmed publisher
  7. Fujiwara M, Nagatomo A, Tsuda M, Obata S, Sakuma T, Yamamoto T, et al. Desmocollin-2 alone forms functional desmosomal plaques, with the plaque formation requiring the juxtamembrane region and plakophilins. J Biochem. 2015;158:339-53 pubmed publisher
  8. Gendronneau G, Sanii S, Dang T, Deshayes F, Delacour D, Pichard E, et al. Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair. PLoS ONE. 2015;10:e0119031 pubmed publisher
  9. Heikinheimo K, Kurppa K, Laiho A, Peltonen S, Berdal A, Bouattour A, et al. Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor. J Dent Res. 2015;94:101-11 pubmed publisher
  10. Gordon K, Kochkodan J, Blatt H, Lin S, Kaplan N, Johnston A, et al. Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis. J Invest Dermatol. 2013;133:712-722 pubmed publisher
  11. Wex T, Kuester D, Monkemuller K, Stahr A, Fry L, Kandulski A, et al. Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection. Hum Pathol. 2012;43:1745-54 pubmed publisher
  12. Chkourko H, Guerrero Serna G, Lin X, Darwish N, Pohlmann J, Cook K, et al. Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization. Heart Rhythm. 2012;9:1133-1140.e6 pubmed publisher
  13. Wex T, Monkemuller K, Stahr A, Kuester D, Fry L, Völkel S, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa. Histopathology. 2012;60:405-15 pubmed publisher
  14. Lin S, Gordon K, Kaplan N, Getsios S. Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1. Mol Biol Cell. 2010;21:3902-14 pubmed publisher
  15. Kanno M, Aoyama Y, Isa Y, Yamamoto Y, Kitajima Y. P120 catenin is associated with desmogleins when desmosomes are assembled in high-Ca2+ medium but not when disassembled in low-Ca2+ medium in DJM-1 cells. J Dermatol. 2008;35:317-24 pubmed publisher
  16. Yang L, Shirakata Y, Shudou M, Dai X, Tokumaru S, Hirakawa S, et al. New skin-equivalent model from de-epithelialized amnion membrane. Cell Tissue Res. 2006;326:69-77 pubmed