This is a Validated Antibody Database (VAD) review about human Dicer, based on 41 published articles (read how Labome selects the articles), using Dicer antibody in all methods. It is aimed to help Labome visitors find the most suited Dicer antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dicer synonym: DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology Dicer antibody (Cell Signaling Technology, 3363) was used in western blot knockout validation on human samples at 1:1000 (fig 4a). Sci Rep (2018) ncbi
Abcam
mouse monoclonal (13D6)
  • western blot; human; loading ...; fig 6c
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples (fig 6c). Cell Death Dis (2019) ncbi
mouse monoclonal (13D6)
  • western blot; human; loading ...; fig 3b
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples (fig 3b). Cell (2019) ncbi
mouse monoclonal (13D6)
  • western blot; human; loading ...; fig e5a
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples (fig e5a). Nature (2017) ncbi
mouse monoclonal (13D6)
  • immunoprecipitation; human; loading ...; fig 7b
Abcam Dicer antibody (Abcam, Ab14601) was used in immunoprecipitation on human samples (fig 7b). J Virol (2017) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:500; fig 4e
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:500 (fig 4e). Mol Ther (2017) ncbi
mouse monoclonal (13D6)
  • immunoprecipitation; human; loading ...; fig 6b
  • western blot; human; loading ...; fig s4d
  • western blot; mouse; loading ...; fig 6b
Abcam Dicer antibody (Abcam, ab14601) was used in immunoprecipitation on human samples (fig 6b), in western blot on human samples (fig s4d) and in western blot on mouse samples (fig 6b). PLoS Biol (2016) ncbi
mouse monoclonal (13D6)
  • western blot; human; fig 6
Abcam Dicer antibody (abcam, ab14601) was used in western blot on human samples (fig 6). RNA (2016) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:1000; fig s8
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:1000 (fig s8). Nat Commun (2016) ncbi
mouse monoclonal (13D6)
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 3b
Abcam Dicer antibody (Abcam, ab14601) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 3b). Nucleic Acids Res (2016) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:1000; fig 2
Abcam Dicer antibody (abcam, ab14601) was used in western blot on human samples at 1:1000 (fig 2). Sci Rep (2015) ncbi
mouse monoclonal (13D6)
  • immunocytochemistry; human; 1:500; fig 2
Abcam Dicer antibody (Abcam, ab14601) was used in immunocytochemistry on human samples at 1:500 (fig 2). J Cell Mol Med (2015) ncbi
mouse monoclonal (13D6)
  • western blot; pigs ; 1:1000
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on pigs samples at 1:1000. Anim Genet (2014) ncbi
mouse monoclonal (13D6)
  • western blot; human
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . Biomed Res Int (2014) ncbi
mouse monoclonal (13D6)
  • immunohistochemistry - paraffin section; human
Abcam Dicer antibody (Abcam, ab14601) was used in immunohistochemistry - paraffin section on human samples . Acta Otolaryngol (2014) ncbi
mouse monoclonal (13D6)
  • western blot; human
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . Cell Res (2014) ncbi
mouse monoclonal (13D6)
  • western blot; human
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
mouse monoclonal (13D6)
  • western blot; human
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . PLoS ONE (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:200
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:200. Blood Cancer J (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . Mol Cancer Res (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; fig 2c
In order to study the interaction of p23 and FKBP4 with hAgo2 and their roles in the mechanism of mammalian cell RNAi silencing, Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples (fig 2c). Mol Biol Cell (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:200
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:200. Endocr Relat Cancer (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:1000
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:1000. J Biol Chem (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:500
Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples at 1:500. Oncol Lett (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human
In order to demonstrate the effect of HIV-1 Tat C on miRNA-101 expression in human brain microvascular endothelial cells, Abcam Dicer antibody (Abcam, ab14601) was used in western blot on human samples . J Neurosci (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; 1:1000
Abcam Dicer antibody (Abcam, 13D6) was used in western blot on human samples at 1:1000. Proc Natl Acad Sci U S A (2013) ncbi
mouse monoclonal (13D6)
  • western blot; human; fig 6
Abcam Dicer antibody (Abcam, 13D6) was used in western blot on human samples (fig 6). Oncogene (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-2)
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 1e
Santa Cruz Biotechnology Dicer antibody (Santa Cruz, sc-136981) was used in immunocytochemistry on human samples (fig 4) and in western blot on human samples (fig 1e). J Cell Mol Med (2015) ncbi
mouse monoclonal (A-2)
  • western blot; human; 1:800; fig 2
Santa Cruz Biotechnology Dicer antibody (Santa Cruz, sc-136981) was used in western blot on human samples at 1:800 (fig 2). J Cell Mol Med (2015) ncbi
mouse monoclonal (F-10)
  • western blot; rat; 1:500
In order to investigate the role of mitochondria-associated miRNAs in traumatic brain injury, Santa Cruz Biotechnology Dicer antibody (Santa Cruz Biotechnology, sc-136979) was used in western blot on rat samples at 1:500. Exp Neurol (2015) ncbi
mouse monoclonal (A-2)
  • immunocytochemistry; human
  • western blot; human
In order to examine the generation and function of small RNAs from cytoplasmic RNA viruses, Santa Cruz Biotechnology Dicer antibody (Santa Cruz, sc-136981) was used in immunocytochemistry on human samples and in western blot on human samples . Nucleic Acids Res (2014) ncbi
mouse monoclonal (D-11)
  • western blot; human; 1:200; fig 3
Santa Cruz Biotechnology Dicer antibody (Santa, sc-136980) was used in western blot on human samples at 1:200 (fig 3). Nat Cell Biol (2012) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 5a
  • western blot; human; 1:500; loading ...; fig 2
In order to measure Dicer protein levels in various types of breast cancer samples, MilliporeSigma Dicer antibody (Sigma, HPA000694) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 5a) and in western blot on human samples at 1:500 (fig 2). Hum Pathol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig s1
In order to suggest that that DICER, DROSHA, and DDRNAs recruit DNA damage factors, MilliporeSigma Dicer antibody (Sigma, HPA00694) was used in western blot on human samples at 1:500 (fig s1). J Cell Sci (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:250; fig 1
Novus Biologicals Dicer antibody (Novus Littleton, 71691) was used in immunohistochemistry on mouse samples at 1:250 (fig 1). Front Mol Neurosci (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4i
Cell Signaling Technology Dicer antibody (Cell Signaling, 3363) was used in western blot on human samples (fig 4i). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (D38E7)
  • western blot; human; 1:1000; loading ...; fig s5c, s8a
Cell Signaling Technology Dicer antibody (Cell Signaling, D38E7) was used in western blot on human samples at 1:1000 (fig s5c, s8a). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Dicer antibody (Cell Signaling, 3363S) was used in western blot on human samples (fig 3b). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology Dicer antibody (Cell Signaling Technology, 3363) was used in western blot knockout validation on human samples at 1:1000 (fig 4a). Sci Rep (2018) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 4a
  • immunocytochemistry; human; loading ...; fig 8a
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology Dicer antibody (CST, 3363) was used in immunoprecipitation on human samples (fig 4a), in immunocytochemistry on human samples (fig 8a) and in western blot on human samples (fig 1b). Biochim Biophys Acta Gene Regul Mech (2017) ncbi
domestic rabbit monoclonal (D38E7)
  • western blot; human; 1:500; loading ...; fig 6B
Cell Signaling Technology Dicer antibody (Cell Signaling, 5362) was used in western blot on human samples at 1:500 (fig 6B). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D38E7)
  • western blot; human; fig s3b
Cell Signaling Technology Dicer antibody (Cell Signaling, 5362) was used in western blot on human samples (fig s3b). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (D38E7)
  • western blot; human; 1:1000
Cell Signaling Technology Dicer antibody (Cell Signaling, 5362) was used in western blot on human samples at 1:1000. J Cell Biochem (2016) ncbi
MBL International
  • RNA immunoprecipitation; human
In order to develop reagents to study RNA binding proteins, MBL International Dicer antibody (MBLI, RN030PW) was used in RNA immunoprecipitation on human samples . Mol Cell (2016) ncbi
Articles Reviewed
  1. Yu W, Huang W, Yang Y, Qiu R, Zeng Y, Hou Y, et al. GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer. Cell Death Dis. 2019;10:832 pubmed publisher
  2. Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
  3. Liu Y, Xue M, Du S, Feng W, Zhang K, Zhang L, et al. Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT. Nat Commun. 2019;10:1637 pubmed publisher
  4. Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  5. Kosmidou C, Efstathiou N, Hoang M, Notomi S, Konstantinou E, Hirano M, et al. Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration. Sci Rep. 2018;8:461 pubmed publisher
  6. Takata M, Gonçalves Carneiro D, Zang T, Soll S, York A, Blanco Melo D, et al. CG dinucleotide suppression enables antiviral defence targeting non-self RNA. Nature. 2017;550:124-127 pubmed publisher
  7. Martínez Gil L, Vera Velasco N, Mingarro I. Exploring the Human-Nipah Virus Protein-Protein Interactome. J Virol. 2017;91: pubmed publisher
  8. Patne K, Rakesh R, Arya V, Chanana U, Sethy R, Swer P, et al. BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage. Biochim Biophys Acta Gene Regul Mech. 2017;1860:936-951 pubmed publisher
  9. Wu Q, Yan H, Tao S, Wang X, Mou L, Chen P, et al. XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p. Oncotarget. 2017;8:16784-16800 pubmed publisher
  10. Beltrami C, Besnier M, Shantikumar S, Shearn A, Rajakaruna C, Laftah A, et al. Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis. Mol Ther. 2017;25:679-693 pubmed publisher
  11. Happel C, Ramalingam D, Ziegelbauer J. Virus-Mediated Alterations in miRNA Factors and Degradation of Viral miRNAs by MCPIP1. PLoS Biol. 2016;14:e2000998 pubmed publisher
  12. Warner M, Bridge K, Hewitson J, Hodgkinson M, Heyam A, Massa B, et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res. 2016;44:9942-9955 pubmed
  13. Spoelstra N, Cittelly D, Christenson J, Gordon M, Elias A, Jedlicka P, et al. Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison. Hum Pathol. 2016;56:40-51 pubmed publisher
  14. Kalantari R, Hicks J, Li L, Gagnon K, Sridhara V, Lemoff A, et al. Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells. RNA. 2016;22:1085-98 pubmed publisher
  15. Tapocik J, Ceniccola K, Mayo C, Schwandt M, Solomon M, Wang B, et al. MicroRNAs Are Involved in the Development of Morphine-Induced Analgesic Tolerance and Regulate Functionally Relevant Changes in Serpini1. Front Mol Neurosci. 2016;9:20 pubmed publisher
  16. Salzman D, Nakamura K, Nallur S, Dookwah M, Metheetrairut C, Slack F, et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun. 2016;7:10954 pubmed publisher
  17. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  18. Francia S, Cabrini M, Matti V, Oldani A, d Adda di Fagagna F. DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors. J Cell Sci. 2016;129:1468-76 pubmed publisher
  19. Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
  20. Boratyn E, Nowak I, Horwacik I, Durbas M, Mistarz A, Kukla M, et al. Monocyte Chemoattractant Protein-Induced Protein 1 Overexpression Modulates Transcriptome, Including MicroRNA, in Human Neuroblastoma Cells. J Cell Biochem. 2016;117:694-707 pubmed publisher
  21. Matsui M, Li L, Janowski B, Corey D. Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors. Sci Rep. 2015;5:12855 pubmed publisher
  22. Jiang Z, Kong C, Zhang Z, Zhu Y, Zhang Y, Chen X. Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer. J Cell Mol Med. 2015;19:1085-93 pubmed publisher
  23. Sun X, Tang S, Xu C, Wang C, Qin S, Du N, et al. DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1. J Cell Mol Med. 2015;19:1357-65 pubmed publisher
  24. Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed publisher
  25. Weng K, Hung C, Hsieh P, Li M, Chen G, Kung Y, et al. A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells. Nucleic Acids Res. 2014;42:12789-805 pubmed publisher
  26. Li R, Jia Y, Zou H, Zhao R. Breed-specific expression of DROSHA, DICER and AGO2 is regulated by glucocorticoid-mediated miRNAs in the liver of newborn piglets. Anim Genet. 2014;45:817-26 pubmed publisher
  27. Liao Y, Lin T, Chen C, Lin S, Au L. The antileukemia activity of natural product HQ17(3) is possibly associated with downregulation of miR-17-92 cluster. Biomed Res Int. 2014;2014:306718 pubmed publisher
  28. Gao C, Li X, Tong B, Wu K, Liu Y, Anniko M, et al. Up-regulated expression of Dicer reveals poor prognosis in laryngeal squamous cell carcinoma. Acta Otolaryngol. 2014;134:959-63 pubmed publisher
  29. Gao M, Wei W, Li M, Wu Y, Ba Z, Jin K, et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res. 2014;24:532-41 pubmed publisher
  30. Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K, Totoki Y, et al. Involvement of telomerase reverse transcriptase in heterochromatin maintenance. Mol Cell Biol. 2014;34:1576-93 pubmed publisher
  31. Chen Y, Thang M, Chan Y, Huang Y, Ma N, Yu A, et al. Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PLoS ONE. 2013;8:e82751 pubmed publisher
  32. Caramuta S, Lee L, Ozata D, Akçakaya P, Georgii Hemming P, Xie H, et al. Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma. Blood Cancer J. 2013;3:e152 pubmed publisher
  33. Huang J, Wang Y, Dhillon K, Calses P, Villegas E, Mitchell P, et al. Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity. Mol Cancer Res. 2013;11:1564-73 pubmed publisher
  34. Pare J, LaPointe P, Hobman T. Hsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cells. Mol Biol Cell. 2013;24:2303-10 pubmed publisher
  35. Caramuta S, Lee L, Ozata D, Akçakaya P, Xie H, Höög A, et al. Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma. Endocr Relat Cancer. 2013;20:551-64 pubmed publisher
  36. Narayanan A, Iordanskiy S, Das R, Van Duyne R, Santos S, Jaworski E, et al. Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA. J Biol Chem. 2013;288:20014-33 pubmed publisher
  37. Kuang Y, Cai J, Li D, Han Q, Cao J, Wang Z. Repression of Dicer is associated with invasive phenotype and chemoresistance in ovarian cancer. Oncol Lett. 2013;5:1149-1154 pubmed
  38. Mishra R, Singh S. HIV-1 Tat C modulates expression of miRNA-101 to suppress VE-cadherin in human brain microvascular endothelial cells. J Neurosci. 2013;33:5992-6000 pubmed publisher
  39. Maute R, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, et al. tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma. Proc Natl Acad Sci U S A. 2013;110:1404-9 pubmed publisher
  40. Tumaneng K, Schlegelmilch K, Russell R, Yimlamai D, Basnet H, Mahadevan N, et al. YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29. Nat Cell Biol. 2012;14:1322-9 pubmed
  41. Ballarino M, Jobert L, Dembele D, de la Grange P, Auboeuf D, Tora L. TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs. Oncogene. 2013;32:4646-55 pubmed publisher