This is a Validated Antibody Database (VAD) review about human Daxx, based on 15 published articles (read how Labome selects the articles), using Daxx antibody in all methods. It is aimed to help Labome visitors find the most suited Daxx antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Daxx synonym: BING2; DAP6; EAP1; death domain-associated protein 6; CENP-C binding protein; ETS1-associated protein 1; Fas-binding protein; death-associated protein 6; fas death domain-associated protein

Santa Cruz Biotechnology
mouse monoclonal (6D345)
  • immunocytochemistry; human; 1:125; loading ...; fig 4b
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology Daxx antibody (Santa Cruz, 6D345) was used in immunocytochemistry on human samples at 1:125 (fig 4b) and in western blot on human samples (fig 4a). Toxicol Appl Pharmacol (2018) ncbi
mouse monoclonal (H-7)
  • immunocytochemistry; mouse; fig 2
Santa Cruz Biotechnology Daxx antibody (Santa Cruz, sc-8043) was used in immunocytochemistry on mouse samples (fig 2). Nat Struct Mol Biol (2011) ncbi
Abcam
rabbit monoclonal (E94)
  • western blot; human; loading ...; fig 2e
Abcam Daxx antibody (Abcam, ab32140) was used in western blot on human samples (fig 2e). Cell Stem Cell (2017) ncbi
Bio-Rad
mouse monoclonal (DAXX-01)
  • immunocytochemistry; human; 1:1000; loading ...; fig 6b
Bio-Rad Daxx antibody (AbD Serotech, MCA2143) was used in immunocytochemistry on human samples at 1:1000 (fig 6b). J Virol (2016) ncbi
MilliporeSigma
rabbit polyclonal
  • immunohistochemistry; human; 1:500; fig 2
MilliporeSigma Daxx antibody (Sigma-Aldrich, HPA008736) was used in immunohistochemistry on human samples at 1:500 (fig 2). PLoS Genet (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 6
MilliporeSigma Daxx antibody (Sigma, D7810) was used in immunocytochemistry on human samples (fig 6). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:250; fig 3b
MilliporeSigma Daxx antibody (Sigma-Aldrich, HPA008736) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 3b). Br J Cancer (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1c
  • chromatin immunoprecipitation; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 2d
MilliporeSigma Daxx antibody (Sigma, D7810) was used in immunohistochemistry - paraffin section on human samples (fig 1c), in chromatin immunoprecipitation on human samples (fig 3b) and in western blot on human samples (fig 2d). Clin Oral Investig (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig s3b
MilliporeSigma Daxx antibody (Sigma, D7810) was used in immunoprecipitation on human samples (fig s3b). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 3, 4, 5, 7
MilliporeSigma Daxx antibody (Sigma, HPA008736) was used in western blot on human samples (fig 3, 4, 5, 7). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:75; fig 1b
MilliporeSigma Daxx antibody (Sigma-Aldrich, HPA008736) was used in immunohistochemistry - paraffin section on human samples at 1:75 (fig 1b). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:500; fig 1e-1f
MilliporeSigma Daxx antibody (Sigma-Aldrich, HPA008736) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1e-1f). J Surg Res (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
MilliporeSigma Daxx antibody (Sigma-Aldrich, D7810) was used in western blot on human samples (fig 4). J Virol (2013) ncbi
Cell Signaling Technology
rabbit monoclonal (25C12)
  • western blot; human; loading ...; fig 2
In order to report the effects of NVP-CGM097 on the p53wildtype GOT1 cells, Cell Signaling Technology Daxx antibody (Cell Signaling, 4533) was used in western blot on human samples (fig 2). Neuroendocrinology (2018) ncbi
rabbit monoclonal (25C12)
  • western blot; human
Cell Signaling Technology Daxx antibody (Cell Signaling, 25C12) was used in western blot on human samples . Genes Dev (2012) ncbi
Articles Reviewed
  1. Hirano S, Udagawa O, Kobayashi Y, Kato A. Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells. Toxicol Appl Pharmacol. 2018;360:150-159 pubmed publisher
  2. Zhu Z, Li C, Zeng Y, Ding J, Qu Z, Gu J, et al. PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs. Cell Stem Cell. 2017;20:274-289.e7 pubmed publisher
  3. Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher
  4. Sloan E, Orr A, Everett R. MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus. J Virol. 2016;90:8621-33 pubmed publisher
  5. Mäkinen N, Aavikko M, Heikkinen T, Taipale M, Taipale J, Koivisto Korander R, et al. Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12. PLoS Genet. 2016;12:e1005850 pubmed publisher
  6. Pinder J, Salsman J, Dellaire G. Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing. Nucleic Acids Res. 2015;43:9379-92 pubmed publisher
  7. Yoshida M, Ogawa R, Yoshida H, Maeshima A, Kanai Y, Kinoshita T, et al. TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast. Br J Cancer. 2015;113:1244-8 pubmed publisher
  8. Lin G, Huang Y, Lin C, Huang S, Shih H, Sytwu H, et al. Daxx and TCF4 interaction links to oral squamous cell carcinoma growth by promoting cell cycle progression via induction of cyclin D1 expression. Clin Oral Investig. 2016;20:533-40 pubmed publisher
  9. Clynes D, Jelinska C, Xella B, Ayyub H, Scott C, Mitson M, et al. Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nat Commun. 2015;6:7538 pubmed publisher
  10. Napier C, Huschtscha L, Harvey A, Bower K, Noble J, Hendrickson E, et al. ATRX represses alternative lengthening of telomeres. Oncotarget. 2015;6:16543-58 pubmed
  11. Fishbein L, Khare S, Wubbenhorst B, Desloover D, D Andrea K, Merrill S, et al. Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas. Nat Commun. 2015;6:6140 pubmed publisher
  12. Geis C, Fendrich V, Rexin P, Di Fazio P, Bartsch D, Ocker M, et al. Ileal neuroendocrine tumors show elevated activation of mammalian target of rapamycin complex. J Surg Res. 2015;194:388-93 pubmed publisher
  13. Glass M, Everett R. Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection. J Virol. 2013;87:2174-85 pubmed publisher
  14. Ratnakumar K, Duarte L, LeRoy G, Hasson D, Smeets D, Vardabasso C, et al. ATRX-mediated chromatin association of histone variant macroH2A1 regulates ?-globin expression. Genes Dev. 2012;26:433-8 pubmed publisher
  15. Iwase S, Xiang B, Ghosh S, Ren T, Lewis P, Cochrane J, et al. ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome. Nat Struct Mol Biol. 2011;18:769-76 pubmed publisher