This is a Validated Antibody Database (VAD) review about human DYNC1LI2, based on 2 published articles (read how Labome selects the articles), using DYNC1LI2 antibody in all methods. It is aimed to help Labome visitors find the most suited DYNC1LI2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DYNC1LI2 synonym: DNCLI2; LIC2; cytoplasmic dynein 1 light intermediate chain 2; LIC-2; LIC53/55; dynein light intermediate chain 2, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 2

Abcam
rabbit polyclonal
  • western blot; zebrafish ; 1:500; loading ...; fig 6a
  • immunocytochemistry; human; 1:100; loading ...; fig s1a
  • western blot; human; 1:1000; loading ...; fig s1c
In order to determine that Light Intermediate Chain 2-dynein is a major mediator of proper spindle orientation and uncover its underlying molecular mechanism, Abcam DYNC1LI2 antibody (Abcam, ab174895) was used in western blot on zebrafish samples at 1:500 (fig 6a), in immunocytochemistry on human samples at 1:100 (fig s1a) and in western blot on human samples at 1:1000 (fig s1c). Sci Rep (2016) ncbi
rabbit monoclonal (EPR11230(2))
  • western blot; zebrafish ; 1:500; loading ...; fig 6a
  • immunocytochemistry; human; 1:100; loading ...; fig s1a
  • western blot; human; 1:1000; loading ...; fig s1c
In order to determine that Light Intermediate Chain 2-dynein is a major mediator of proper spindle orientation and uncover its underlying molecular mechanism, Abcam DYNC1LI2 antibody (Abcam, ab178702) was used in western blot on zebrafish samples at 1:500 (fig 6a), in immunocytochemistry on human samples at 1:100 (fig s1a) and in western blot on human samples at 1:1000 (fig s1c). Sci Rep (2016) ncbi
rabbit monoclonal (EPR11230(2))
  • western blot; human; 1:500; fig 2
In order to examine the function of light chain intermediate 2 during mitosis, Abcam DYNC1LI2 antibody (Abcam, ab178702) was used in western blot on human samples at 1:500 (fig 2). PLoS ONE (2016) ncbi
Invitrogen
rabbit polyclonal
  • immunocytochemistry; human; 1:50; fig 1
  • western blot; human; 1:500; fig 2
In order to examine the function of light chain intermediate 2 during mitosis, Invitrogen DYNC1LI2 antibody (Thermo-Scientifi, PA5-25392) was used in immunocytochemistry on human samples at 1:50 (fig 1) and in western blot on human samples at 1:500 (fig 2). PLoS ONE (2016) ncbi
Articles Reviewed
  1. Mahale S, Kumar M, Sharma A, Babu A, Ranjan S, Sachidanandan C, et al. The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation. Sci Rep. 2016;6:22 pubmed publisher
  2. Mahale S, Sharma A, Mylavarapu S. Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint. PLoS ONE. 2016;11:e0159646 pubmed publisher