This is a Validated Antibody Database (VAD) review about human DVL2, based on 22 published articles (read how Labome selects the articles), using DVL2 antibody in all methods. It is aimed to help Labome visitors find the most suited DVL2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:5000; loading ...; fig 1a
Cell Signaling Technology DVL2 antibody (Cell signaling, 3216) was used in western blot knockout validation on human samples at 1:5000 (fig 1a). J Cell Sci (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-4)
  • western blot; mouse; 1:200; fig 6a
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology, sc-166303) was used in western blot on mouse samples at 1:200 (fig 6a). Fluids Barriers CNS (2021) ncbi
mouse monoclonal (D-6)
  • western blot; human; 1:1000; loading ...; fig 5c
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology, sc-390303) was used in western blot on human samples at 1:1000 (fig 5c). FEBS Open Bio (2021) ncbi
mouse monoclonal (B-4)
  • western blot; human; loading ...; fig 4e
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz, sc-166303) was used in western blot on human samples (fig 4e). J Biol Chem (2021) ncbi
mouse monoclonal (B-4)
  • western blot; human; loading ...; fig 6e
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz, sc-166303) was used in western blot on human samples (fig 6e). iScience (2020) ncbi
mouse monoclonal (10B5)
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3c
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology Inc, sc-8026) was used in immunocytochemistry on mouse samples at 1:500 (fig 3c). Mol Neurobiol (2017) ncbi
mouse monoclonal (10B5)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
In order to demonstrate a role for APPL1 in regulating Dvl2-dependent transcriptional activity of AP-1, Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology, sc-8026) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). FEBS Lett (2015) ncbi
mouse monoclonal (B-4)
  • immunohistochemistry - paraffin section; human; 1:25
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology, sc-166303) was used in immunohistochemistry - paraffin section on human samples at 1:25. PLoS ONE (2014) ncbi
mouse monoclonal (10B5)
  • immunohistochemistry; mouse; fig 6
Santa Cruz Biotechnology DVL2 antibody (Santa Cruz Biotechnology, sc-8026) was used in immunohistochemistry on mouse samples (fig 6). Biol Open (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6c, 6d
Abcam DVL2 antibody (Abcam, ab22616) was used in western blot on human samples at 1:1000 (fig 6c, 6d). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (EPNCIR145)
  • western blot; human; loading ...; fig 4c
Abcam DVL2 antibody (Abcam, ab124933) was used in western blot on human samples (fig 4c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (EPNCIR145)
  • western blot; human; 1:2000; fig 4
Abcam DVL2 antibody (Abcam, ab124933) was used in western blot on human samples at 1:2000 (fig 4). Nat Commun (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (30D2)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5c
  • western blot; mouse; 1:1000; loading ...; fig 5a
  • immunohistochemistry; rhesus macaque; 1:100; loading ...; fig 5f
  • western blot; rhesus macaque; 1:1000; fig 5d
Cell Signaling Technology DVL2 antibody (Cell Signaling Technology, 3224S) was used in immunohistochemistry on mouse samples at 1:100 (fig 5c), in western blot on mouse samples at 1:1000 (fig 5a), in immunohistochemistry on rhesus macaque samples at 1:100 (fig 5f) and in western blot on rhesus macaque samples at 1:1000 (fig 5d). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (30D2)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 5a
  • western blot; human; 1:1000; loading ...; fig 5b
Cell Signaling Technology DVL2 antibody (CST, 3224S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 5a) and in western blot on human samples at 1:1000 (fig 5b). Circulation (2021) ncbi
domestic rabbit monoclonal (30D2)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology DVL2 antibody (Cell Signaling, 30D2) was used in western blot on mouse samples (fig 4c). Science (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 2e
Cell Signaling Technology DVL2 antibody (CST, 3216) was used in immunoprecipitation on human samples (fig 2e). elife (2017) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; 1:5000; loading ...; fig 1a
Cell Signaling Technology DVL2 antibody (Cell signaling, 3216) was used in western blot knockout validation on human samples at 1:5000 (fig 1a). J Cell Sci (2016) ncbi
domestic rabbit monoclonal (30D2)
  • western blot; human; loading ...; fig s9b
In order to report that frizzled family proteins are receptors for Clostridium difficile toxin B, Cell Signaling Technology DVL2 antibody (Cell Signaling, 30D2) was used in western blot on human samples (fig s9b). Nature (2016) ncbi
domestic rabbit monoclonal (30D2)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology DVL2 antibody (Cell Signaling, 3224) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s5
Cell Signaling Technology DVL2 antibody (cell signalling, 3216) was used in western blot on human samples (fig s5). Breast Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:1000; loading ...; fig s2b
  • western blot; human; 1:1000; fig s4a
In order to research the Wnt5a/DVL1 signaling pathway and its role on ribosomal DNA transcription, Cell Signaling Technology DVL2 antibody (Cell Signaling, 3216) was used in immunocytochemistry on human samples at 1:1000 (fig s2b) and in western blot on human samples at 1:1000 (fig s4a). PLoS Genet (2016) ncbi
domestic rabbit monoclonal (30D2)
  • western blot; human; 1:2000; fig 4
Cell Signaling Technology DVL2 antibody (Cell Signaling Technology, 3224) was used in western blot on human samples at 1:2000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (30D2)
  • immunohistochemistry - free floating section; mouse; 1:300
In order to assess the effects of Shenling Baizhu San on colitis-associated colorectal cancer, Cell Signaling Technology DVL2 antibody (CST, 30D2) was used in immunohistochemistry - free floating section on mouse samples at 1:300. BMC Complement Altern Med (2015) ncbi
domestic rabbit monoclonal (30D2)
  • western blot; human
Cell Signaling Technology DVL2 antibody (Cell Signaling Technology, 30D2) was used in western blot on human samples . Cell Mol Life Sci (2014) ncbi
Articles Reviewed
  1. Zhong G, Zhao D, Li J, Liu Z, Pan J, Yuan X, et al. WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity. Front Cell Dev Biol. 2021;9:739944 pubmed publisher
  2. He W, Lu Q, Sherchan P, Huang L, Hu X, Zhang J, et al. Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice. Fluids Barriers CNS. 2021;18:44 pubmed publisher
  3. Zhang H, Yang X, Zhu L, Li Z, Zuo P, Wang P, et al. ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradation. FEBS Open Bio. 2021;11:2784-2799 pubmed publisher
  4. Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed publisher
  5. Ear J, Abd El Hafeez A, Roy S, Ngo T, Rajapakse N, Choi J, et al. A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding. J Biol Chem. 2021;296:100493 pubmed publisher
  6. Ear J, Saklecha A, Rajapakse N, Choi J, Ghassemian M, Kufareva I, et al. Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. iScience. 2020;23:100859 pubmed publisher
  7. Liao S, Chen H, Liu M, Gan L, Li C, Zhang W, et al. Aquaporin 9 inhibits growth and metastasis of hepatocellular carcinoma cells via Wnt/β-catenin pathway. Aging (Albany NY). 2020;12:1527-1544 pubmed publisher
  8. Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed publisher
  9. Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher
  10. Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S. The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. elife. 2017;6: pubmed publisher
  11. Gammons M, Rutherford T, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016;129:3892-3902 pubmed
  12. Chen S, Zhang Q, Bai B, Ouyang S, Bao Y, Li H, et al. MARK2/Par1b Insufficiency Attenuates DVL Gene Transcription via Histone Deacetylation in Lumbosacral Spina Bifida. Mol Neurobiol. 2017;54:6304-6316 pubmed publisher
  13. Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature. 2016;538:350-355 pubmed publisher
  14. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  15. Sikora M, Jacobsen B, Levine K, Chen J, Davidson N, Lee A, et al. WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines. Breast Cancer Res. 2016;18:92 pubmed publisher
  16. Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet. 2016;12:e1006217 pubmed publisher
  17. Shnitsar I, Bashkurov M, Masson G, Ogunjimi A, Mosessian S, Cabeza E, et al. PTEN regulates cilia through Dishevelled. Nat Commun. 2015;6:8388 pubmed publisher
  18. Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  19. Banach Orlowska M, Szymańska E, Miaczynska M. APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription. FEBS Lett. 2015;589:532-9 pubmed publisher
  20. Zhao H, Xie C, Lin X, Zhao Y, Han Y, Fan C, et al. Coexpression of IQ-domain GTPase-activating protein 1 (IQGAP1) and Dishevelled (Dvl) is correlated with poor prognosis in non-small cell lung cancer. PLoS ONE. 2014;9:e113713 pubmed publisher
  21. Liu C, Lin C, Gao C, May Simera H, Swaroop A, Li T. Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a. Biol Open. 2014;3:861-70 pubmed publisher
  22. Knoblich K, Wang H, Sharma C, Fletcher A, Turley S, Hemler M. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits ?-catenin degradation. Cell Mol Life Sci. 2014;71:1305-14 pubmed publisher