This is a Validated Antibody Database (VAD) review about human DOCK8, based on 3 published articles (read how Labome selects the articles), using DOCK8 antibody in all methods. It is aimed to help Labome visitors find the most suited DOCK8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DOCK8 synonym: HEL-205; MRD2; ZIR8; dedicator of cytokinesis protein 8; 1200017A24Rik; epididymis luminal protein 205

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (G-2)
  • western blot knockout validation; human; loading ...; fig 4a
  • western blot knockout validation; mouse; loading ...; fig 1b
Santa Cruz Biotechnology DOCK8 antibody (SantaCruz, SC-376911) was used in western blot knockout validation on human samples (fig 4a) and in western blot knockout validation on mouse samples (fig 1b). J Clin Invest (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-2)
  • western blot knockout validation; human; loading ...; fig 4a
  • western blot knockout validation; mouse; loading ...; fig 1b
Santa Cruz Biotechnology DOCK8 antibody (SantaCruz, SC-376911) was used in western blot knockout validation on human samples (fig 4a) and in western blot knockout validation on mouse samples (fig 1b). J Clin Invest (2016) ncbi
Proteintech Group
rabbit polyclonal
  • immunoprecipitation; human; fig 5
  • western blot; human; fig 5
Proteintech Group DOCK8 antibody (Proteintech, 11622-1-AP) was used in immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 5). Oncotarget (2015) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; mouse
Sigma-Aldrich DOCK8 antibody (Sigma, HPA003218) was used in western blot on mouse samples . Nat Immunol (2012) ncbi
Articles Reviewed
  1. Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, et al. A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton. J Clin Invest. 2016;126:3837-3851 pubmed publisher
  2. Wang S, Cui H, Liu Y, Zhao P, Zhang Y, Fu Z, et al. CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells. Oncotarget. 2015;6:243-57 pubmed
  3. Jabara H, McDonald D, Janssen E, Massaad M, Ramesh N, Borzutzky A, et al. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol. 2012;13:612-20 pubmed publisher