This is a Validated Antibody Database (VAD) review about human DNA2, based on 7 published articles (read how Labome selects the articles), using DNA2 antibody in all methods. It is aimed to help Labome visitors find the most suited DNA2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNA2 synonym: DNA2L; hDNA2; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication ATP-dependent helicase-like homolog; DNA replication helicase 2 homolog; DNA2 DNA replication helicase 2-like; DNA2-like helicase

Abcam
rabbit polyclonal
  • western blot; human; loading ...; fig s4a
Abcam DNA2 antibody (Abcam, ab96488) was used in western blot on human samples (fig s4a). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Abcam DNA2 antibody (Abcam, ab 96488) was used in western blot on human samples (fig 4a). Mol Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a, 5b
Abcam DNA2 antibody (Abcam, ab96488) was used in western blot on human samples (fig 2a, 5b). Genes Dev (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Abcam DNA2 antibody (Abcam, ab96488) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; human; 1:1000; fig 5
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Abcam DNA2 antibody (Abcam, ab96488) was used in chromatin immunoprecipitation on human samples at 1:1000 (fig 5). J Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
In order to study the effect of ASF1 depletion on the alternative lengthening of telomeres, Abcam DNA2 antibody (Abcam, ab96488) was used in western blot on human samples at 1:1000. Nat Struct Mol Biol (2014) ncbi
rabbit polyclonal
  • western blot; human
Abcam DNA2 antibody (Abcam, ab96488) was used in western blot on human samples . J Biol Chem (2012) ncbi
Articles Reviewed
  1. Tian Y, Shen X, Wang R, Klages Mundt N, Lynn E, Martin S, et al. Constitutive role of the Fanconi anemia D2 gene in the replication stress response. J Biol Chem. 2017;292:20184-20195 pubmed publisher
  2. Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed publisher
  3. Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher
  4. Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher
  5. Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher
  6. O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
  7. van Wietmarschen N, Moradian A, Morin G, Lansdorp P, Uringa E. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly. J Biol Chem. 2012;287:43351-8 pubmed publisher