This is a Validated Antibody Database (VAD) review about human DNA polymerase beta, based on 13 published articles (read how Labome selects the articles), using DNA polymerase beta antibody in all methods. It is aimed to help Labome visitors find the most suited DNA polymerase beta antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNA polymerase beta synonym: DNA polymerase beta; DNA pol beta; DNA polymerase beta subunit; polymerase (DNA directed), beta; polymerase (DNA) beta

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s9b
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot knockout validation on human samples at 1:1000 (fig s9b). Nature (2018) ncbi
Abcam
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 5a
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot on human samples at 1:2000 (fig 5a). Nucleic Acids Res (2018) ncbi
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s9b
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot knockout validation on human samples at 1:1000 (fig s9b). Nature (2018) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig s7
  • western blot; human; loading ...; fig s2b
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in immunohistochemistry - paraffin section on human samples (fig s7) and in western blot on human samples (fig s2b). Nucleic Acids Res (2018) ncbi
rabbit polyclonal
  • western blot knockout validation; human; 1:1000; loading ...; fig s1b
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot knockout validation on human samples at 1:1000 (fig s1b). Nat Commun (2018) ncbi
mouse monoclonal (61)
  • western blot; mouse; loading ...; fig 1c
Abcam DNA polymerase beta antibody (Abcam, ab1831) was used in western blot on mouse samples (fig 1c). Nucleic Acids Res (2018) ncbi
rabbit monoclonal (EPR12722(B))
  • western blot; human; loading ...; fig 1c
Abcam DNA polymerase beta antibody (Abcam, ab175197) was used in western blot on human samples (fig 1c). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in western blot on human samples at 1:1000 (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal
In order to report a Cd-mediated impairment of BER pathway at sub-lethal doses, Abcam DNA polymerase beta antibody (Abcam, ab26343) was used . DNA Repair (Amst) (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig st1
Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in immunohistochemistry - paraffin section on human samples (fig st1). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200
In order to study the effect of cellular XRCC1 oxidation on PARP-mediated DNA damage responses, Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in immunocytochemistry on mouse samples at 1:200. DNA Repair (Amst) (2013) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 4
  • immunocytochemistry; human; 1:200; fig 6
  • western blot; human; fig 6
In order to study the functional significance of the DNA polymerase-beta interaction with BRCA1, Abcam DNA polymerase beta antibody (Abcam, ab26343) was used in immunoprecipitation on human samples (fig 4), in immunocytochemistry on human samples at 1:200 (fig 6) and in western blot on human samples (fig 6). PLoS ONE (2013) ncbi
Invitrogen
mouse monoclonal (18S)
  • western blot; human; 1:5000; fig s1b
In order to investigate the role of protein stability in the choice of DNA repair mechanism, Invitrogen DNA polymerase beta antibody (Thermo, 18S) was used in western blot on human samples at 1:5000 (fig s1b). Nat Commun (2014) ncbi
mouse monoclonal (61)
  • western blot; human; 1:1000; fig s2a
In order to investigate the role of protein stability in the choice of DNA repair mechanism, Invitrogen DNA polymerase beta antibody (Thermo, 61) was used in western blot on human samples at 1:1000 (fig s2a). Nat Commun (2014) ncbi
mouse monoclonal (61)
  • western blot; mouse; fig 2c
In order to investigate the contribution of the base excision repair pathway to HIV infection, Invitrogen DNA polymerase beta antibody (Neomarkers, MS-1402-P0) was used in western blot on mouse samples (fig 2c). PLoS ONE (2011) ncbi
Articles Reviewed
  1. Slyskova J, Sabatella M, Ribeiro Silva C, Stok C, Theil A, Vermeulen W, et al. Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage. Nucleic Acids Res. 2018;46:9537-9549 pubmed publisher
  2. Zimmermann M, Murina O, Reijns M, Agathanggelou A, Challis R, Tarnauskaitė Ž, et al. CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. Nature. 2018;559:285-289 pubmed publisher
  3. Li M, Yang X, LU X, Dai N, Zhang S, Cheng Y, et al. APE1 deficiency promotes cellular senescence and premature aging features. Nucleic Acids Res. 2018;46:5664-5677 pubmed publisher
  4. Zou X, Owusu M, Harris R, Jackson S, Loizou J, Nik Zainal S. Validating the concept of mutational signatures with isogenic cell models. Nat Commun. 2018;9:1744 pubmed publisher
  5. Ray S, Breuer G, DeVeaux M, Zelterman D, Bindra R, Sweasy J. DNA polymerase beta participates in DNA End-joining. Nucleic Acids Res. 2018;46:242-255 pubmed publisher
  6. Goetze R, Kim D, Schinazi R, Kim B. A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells. J Biol Chem. 2017;292:14016-14025 pubmed publisher
  7. Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M. Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome. PLoS ONE. 2015;10:e0142218 pubmed publisher
  8. Antoniali G, Marcuzzi F, Casarano E, Tell G. Cadmium treatment suppresses DNA polymerase δ catalytic subunit gene expression by acting on the p53 and Sp1 regulatory axis. DNA Repair (Amst). 2015;35:90-105 pubmed publisher
  9. Hwang J, Sung W, Tu H, Hsieh K, Yeh C, Chen C, et al. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS ONE. 2015;10:e0139435 pubmed publisher
  10. Fang Q, Inanç B, Schamus S, Wang X, Wei L, Brown A, et al. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nat Commun. 2014;5:5513 pubmed publisher
  11. Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed publisher
  12. Masaoka A, Gassman N, Horton J, Kedar P, Witt K, Hobbs C, et al. Interaction between DNA Polymerase ? and BRCA1. PLoS ONE. 2013;8:e66801 pubmed publisher
  13. Yoder K, Espeseth A, Wang X, Fang Q, Russo M, Lloyd R, et al. The base excision repair pathway is required for efficient lentivirus integration. PLoS ONE. 2011;6:e17862 pubmed publisher