This is a Validated Antibody Database (VAD) review about human DNA ligase IV, based on 7 published articles (read how Labome selects the articles), using DNA ligase IV antibody in all methods. It is aimed to help Labome visitors find the most suited DNA ligase IV antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNA ligase IV synonym: LIG4S

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D5N5N)
  • western blot knockout validation; human; 1:1000; loading ...; fig 6h
Cell Signaling Technology DNA ligase IV antibody (Cell Signaling, 14649) was used in western blot knockout validation on human samples at 1:1000 (fig 6h). Nat Commun (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR16531)
  • western blot; human; loading ...; fig 3d
Abcam DNA ligase IV antibody (Abcam, ab193353) was used in western blot on human samples (fig 3d). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:100; fig 3a
Abcam DNA ligase IV antibody (Abcam, ab26039) was used in western blot on human samples at 1:100 (fig 3a). Mol Oncol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-8)
  • chromatin immunoprecipitation; human; loading ...; fig S1e
  • immunoprecipitation; human; loading ...; fig 1c
  • western blot; human; loading ...; fig S4a
Santa Cruz Biotechnology DNA ligase IV antibody (Santa cruz, Sc-271299) was used in chromatin immunoprecipitation on human samples (fig S1e), in immunoprecipitation on human samples (fig 1c) and in western blot on human samples (fig S4a). Nat Commun (2016) ncbi
Proteintech Group
domestic rabbit polyclonal
Proteintech Group DNA ligase IV antibody (Proteintech Group, 12695-I-AP) was used . Nat Commun (2015) ncbi
GeneTex
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
GeneTex DNA ligase IV antibody (GeneTex, GTX108820) was used in western blot on human samples (fig 1a). Nat Commun (2016) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:250; fig 4
  • western blot; human; 1:5000; fig 2
In order to learn mediation of Wnt signaling-induced radioresistance by LIG4, MilliporeSigma DNA ligase IV antibody (Sigma, HPA001334) was used in immunohistochemistry on human samples at 1:250 (fig 4) and in western blot on human samples at 1:5000 (fig 2). Nat Commun (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D5N5N)
  • western blot; human; loading ...; fig 3d, e9g
Cell Signaling Technology DNA ligase IV antibody (Cell Signalling, 14649) was used in western blot on human samples (fig 3d, e9g). Nature (2019) ncbi
domestic rabbit monoclonal (D5N5N)
  • western blot knockout validation; human; 1:1000; loading ...; fig 6h
Cell Signaling Technology DNA ligase IV antibody (Cell Signaling, 14649) was used in western blot knockout validation on human samples at 1:1000 (fig 6h). Nat Commun (2016) ncbi
Articles Reviewed
  1. Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed publisher
  2. Vítor A, Sridhara S, Sabino J, Afonso A, Grosso A, Martin R, et al. Single-molecule imaging of transcription at damaged chromatin. Sci Adv. 2019;5:eaau1249 pubmed publisher
  3. Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita R, Sarker A, et al. Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes. Nat Commun. 2016;7:13049 pubmed publisher
  4. Schmid Burgk J, Höning K, Ebert T, Hornung V. CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun. 2016;7:12338 pubmed publisher
  5. Jun S, Jung Y, Suh H, Wang W, Kim M, Oh Y, et al. LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun. 2016;7:10994 pubmed publisher
  6. Rasmussen R, Gajjar M, Jensen K, Hamerlik P. Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma. Mol Oncol. 2016;10:751-63 pubmed publisher
  7. Xing M, Yang M, Huo W, Feng F, Wei L, Jiang W, et al. Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun. 2015;6:6233 pubmed publisher