This is a Validated Antibody Database (VAD) review about human DNA ligase I, based on 6 published articles (read how Labome selects the articles), using DNA ligase I antibody in all methods. It is aimed to help Labome visitors find the most suited DNA ligase I antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DNA ligase I synonym: DNA ligase 1; ligase I, DNA, ATP-dependent; polydeoxyribonucleotide synthase [ATP] 1

Knockout validation
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse; fig s2
Proteintech Group DNA ligase I antibody (Proteintech, 18051-1-AP) was used in western blot knockout validation on mouse samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-5)
Santa Cruz Biotechnology DNA ligase I antibody (Santa Cruz, sc-271678) was used . PLoS Pathog (2017) ncbi
mouse monoclonal (1A9)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology DNA ligase I antibody (Santa Cruz, sc-47703) was used in western blot on human samples (fig 1b). Mol Cell (2017) ncbi
Proteintech Group
rabbit polyclonal
  • western blot knockout validation; mouse; fig s2
Proteintech Group DNA ligase I antibody (Proteintech, 18051-1-AP) was used in western blot knockout validation on mouse samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
rabbit polyclonal
  • western blot; human
Proteintech Group DNA ligase I antibody (Proteintech Group, 18051-1-AP) was used in western blot on human samples . Cell Rep (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; fig 6a
In order to assess the effects of the PCNA S228I mutation that causes proliferating cell nuclear antigen-associated DNA repair disorder, Invitrogen DNA ligase I antibody (Thermo Scientific, PA5-27820) was used in western blot on human samples (fig 6a). DNA Repair (Amst) (2017) ncbi
GeneTex
mouse monoclonal (10H5)
  • western blot; human; fig s2
In order to study the functional significance of the DNA polymerase-beta interaction with BRCA1, GeneTex DNA ligase I antibody (GeneTex Inc, GTX70141) was used in western blot on human samples (fig s2). PLoS ONE (2013) ncbi
Articles Reviewed
  1. Long Q, Yan R, Hu J, Cai D, Mitra B, Kim E, et al. The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation. PLoS Pathog. 2017;13:e1006784 pubmed publisher
  2. Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed publisher
  3. Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed publisher
  4. Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A. 2016;113:1256-60 pubmed publisher
  5. Han L, Masani S, Hsieh C, Yu K. DNA ligase I is not essential for mammalian cell viability. Cell Rep. 2014;7:316-20 pubmed publisher
  6. Masaoka A, Gassman N, Horton J, Kedar P, Witt K, Hobbs C, et al. Interaction between DNA Polymerase ? and BRCA1. PLoS ONE. 2013;8:e66801 pubmed publisher