This is a Validated Antibody Database (VAD) review about human DLG1, based on 11 published articles (read how Labome selects the articles), using DLG1 antibody in all methods. It is aimed to help Labome visitors find the most suited DLG1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DLG1 synonym: DLGH1; SAP-97; SAP97; hdlg

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (2D11)
  • western blot knockout validation; dogs; loading ...; fig s3
  • immunocytochemistry; dogs; loading ...; fig s3
Santa Cruz Biotechnology DLG1 antibody (Santa Cruz, sc-9961) was used in western blot knockout validation on dogs samples (fig s3) and in immunocytochemistry on dogs samples (fig s3). PLoS Pathog (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (2D11)
  • western blot knockout validation; dogs; loading ...; fig s3
  • immunocytochemistry; dogs; loading ...; fig s3
Santa Cruz Biotechnology DLG1 antibody (Santa Cruz, sc-9961) was used in western blot knockout validation on dogs samples (fig s3) and in immunocytochemistry on dogs samples (fig s3). PLoS Pathog (2021) ncbi
mouse monoclonal (2D11)
  • immunohistochemistry; mouse; loading ...; fig 3c
In order to report that SB216763 prevents myocyte injury and cardiac dysfunction in two murine models of arrhythmogenic cardiomyopathy, Santa Cruz Biotechnology DLG1 antibody (Santa Cruz, sc-9961) was used in immunohistochemistry on mouse samples (fig 3c). JCI Insight (2016) ncbi
mouse monoclonal (2D11)
  • immunohistochemistry - paraffin section; human; 1:40; loading ...; fig 1a
  • western blot; human; 1:100; loading ...; fig 4a
In order to study the role of cell polarity determinant human Discs-large in endometrial cancer, Santa Cruz Biotechnology DLG1 antibody (Santa Cruz, sc-9961) was used in immunohistochemistry - paraffin section on human samples at 1:40 (fig 1a) and in western blot on human samples at 1:100 (fig 4a). Br J Cancer (2016) ncbi
mouse monoclonal (2D11)
  • western blot; human; fig 6
Santa Cruz Biotechnology DLG1 antibody (Santa Cruz, sc-9961) was used in western blot on human samples (fig 6). Int J Biochem Cell Biol (2015) ncbi
mouse monoclonal (2D11)
  • immunoprecipitation; human
Santa Cruz Biotechnology DLG1 antibody (Santa Cruz Biotechnology, sc-9961) was used in immunoprecipitation on human samples . J Biol Chem (2013) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...
Invitrogen DLG1 antibody (Thermo, PA1-741) was used in western blot on mouse samples at 1:1000. Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; rat; 1:1000; loading ...; fig 3a
In order to investigate diverging presynaptic and postsynaptic roles of SAP97 N-terminal isoforms in synapse maturation and plasticity, Invitrogen DLG1 antibody (Thermo Scientific, PA1-741) was used in immunocytochemistry on rat samples at 1:1000 (fig 3a). Hippocampus (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 9
In order to analyze modulation by donepezil and diet on mTOR signaling and neuroinflammation in the brain by donepezil and diet, Invitrogen DLG1 antibody (Pierce, PA1-741) was used in western blot on mouse samples (fig 9). Biochim Biophys Acta (2016) ncbi
domestic rabbit polyclonal
In order to identify modulators of corticotropin-releasing hormone receptor type 1 signaling, Invitrogen DLG1 antibody (Thermo Fisher Scientific, PA1-741) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
In order to demonstrate that the dendrite branching promoting action of full length SAP97 is dependent on the PDZ3 domain, Invitrogen DLG1 antibody (ThermoFisher Scientific, PA1-741) was used . Mol Cell Neurosci (2015) ncbi
domestic rabbit polyclonal
In order to explore how the different domains of SAP97 regulate its localization, Invitrogen DLG1 antibody (Thermo, PA1-044) was used . Biochim Biophys Acta (2015) ncbi
Articles Reviewed
  1. Bourgeois J, Wang L, Rabino A, Everitt J, Alvarez M, Awadia S, et al. ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice. PLoS Pathog. 2021;17:e1009713 pubmed publisher
  2. Liu X, Ge J, Chen C, Shen Y, Xie J, Zhu X, et al. FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation. Cell Death Dis. 2021;12:25 pubmed publisher
  3. Goodman L, Baddeley D, Ambroziak W, Waites C, Garner C, Soeller C, et al. N-terminal SAP97 isoforms differentially regulate synaptic structure and postsynaptic surface pools of AMPA receptors. Hippocampus. 2017;27:668-682 pubmed publisher
  4. Chelko S, Asimaki A, Andersen P, Bedja D, Amat Alarcon N, Demazumder D, et al. Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy. JCI Insight. 2016;1: pubmed publisher
  5. Sugihara T, Nakagawa S, Sasajima Y, Ichinose T, Hiraike H, Kondo F, et al. Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer. Br J Cancer. 2016;114:1012-8 pubmed publisher
  6. Dasuri K, Zhang L, Kim S, Bruce Keller A, Keller J. Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta. 2016;1862:274-83 pubmed publisher
  7. Bender J, Engeholm M, Ederer M, Breu J, Møller T, Michalakis S, et al. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. PLoS ONE. 2015;10:e0136768 pubmed publisher
  8. Zhang L, Hsu F, Mojsilovic Petrovic J, Jablonski A, Zhai J, Coulter D, et al. Structure-function analysis of SAP97, a modular scaffolding protein that drives dendrite growth. Mol Cell Neurosci. 2015;65:31-44 pubmed publisher
  9. Menga A, Iacobazzi V, Infantino V, Avantaggiati M, Palmieri F. The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells. Int J Biochem Cell Biol. 2015;60:157-66 pubmed publisher
  10. Hong X, Avetisyan M, Ronilo M, Standley S. SAP97 blocks the RXR ER retention signal of NMDA receptor subunit GluN1-3 through its SH3 domain. Biochim Biophys Acta. 2015;1853:489-99 pubmed publisher
  11. Philippe M, Léger T, Desvaux R, Walch L. Discs large 1 (Dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (AP-1) in forming Weibel-Palade bodies of endothelial cells. J Biol Chem. 2013;288:13046-56 pubmed publisher