This is a Validated Antibody Database (VAD) review about human DKK1, based on 10 published articles (read how Labome selects the articles), using DKK1 antibody in all methods. It is aimed to help Labome visitors find the most suited DKK1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DKK1 synonym: DKK-1; SK

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig 2g
  • western blot knockout validation; mouse; 1:50; loading ...; fig 4b
Santa Cruz Biotechnology DKK1 antibody (SantaCruz, sc-374574) was used in western blot on human samples (fig 2g) and in western blot knockout validation on mouse samples at 1:50 (fig 4b). Int J Biol Sci (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-7)
  • immunocytochemistry; human; loading ...; fig 4a
Santa Cruz Biotechnology DKK1 antibody (Santa Cruz Biotechnology, sc-374574) was used in immunocytochemistry on human samples (fig 4a). iScience (2022) ncbi
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig 2g
  • western blot knockout validation; mouse; 1:50; loading ...; fig 4b
Santa Cruz Biotechnology DKK1 antibody (SantaCruz, sc-374574) was used in western blot on human samples (fig 2g) and in western blot knockout validation on mouse samples at 1:50 (fig 4b). Int J Biol Sci (2021) ncbi
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig 2a, s4b
Santa Cruz Biotechnology DKK1 antibody (Santa Cruz, sc-374574) was used in western blot on human samples (fig 2a, s4b). Int J Mol Sci (2020) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:300; loading ...; fig 3f, 5b
Santa Cruz Biotechnology DKK1 antibody (Santa Cruz Biotechnology, Sc-374574) was used in western blot on human samples at 1:300 (fig 3f, 5b). elife (2020) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:1000; loading ...; fig 4b
Santa Cruz Biotechnology DKK1 antibody (Santa, sc-374574) was used in western blot on human samples at 1:1000 (fig 4b). BMC Gastroenterol (2019) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:500; fig 6
Santa Cruz Biotechnology DKK1 antibody (Santa Cruz, sc-374574) was used in western blot on human samples at 1:500 (fig 6). Oncotarget (2015) ncbi
R&D Systems
mouse monoclonal (141135)
  • immunohistochemistry; human; 1:200; loading ...; fig 6a, 7a
R&D Systems DKK1 antibody (R&D Systems, MAB10962) was used in immunohistochemistry on human samples at 1:200 (fig 6a, 7a). Oncogene (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR4759)
  • western blot; human; 1:5000; loading ...; fig 4b
Abcam DKK1 antibody (Abcam, ab109416) was used in western blot on human samples at 1:5000 (fig 4b). Oncol Lett (2017) ncbi
Abnova
mouse monoclonal (2A5)
  • immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 2c
Abnova DKK1 antibody (Abnova, H00022943-M11) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 2c). J Neurosurg Pediatr (2014) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:100; loading ...; fig s2j
Cell Signaling Technology DKK1 antibody (Cell Signalling, 4687) was used in western blot on human samples at 1:100 (fig s2j). Nat Commun (2019) ncbi
Articles Reviewed
  1. Cai S, Hu T, Venkatesan M, Allam M, Schneider F, Ramalingam S, et al. Multiplexed protein profiling reveals spatial subcellular signaling networks. iScience. 2022;25:104980 pubmed publisher
  2. Kimura H, Sada R, Takada N, Harada A, Doki Y, Eguchi H, et al. The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers. Oncogene. 2021;40:4486-4502 pubmed publisher
  3. Zheng T, Liu X, Li X, Wang Q, Zhao Y, Li X, et al. Dickkopf-1 promotes Vascular Smooth Muscle Cell proliferation and migration through upregulating UHRF1 during Cyclic Stretch application. Int J Biol Sci. 2021;17:1234-1249 pubmed publisher
  4. Nam B, Park H, Lee Y, Oh Y, Park J, Kim S, et al. TGFβ1 Suppressed Matrix Mineralization of Osteoblasts Differentiation by Regulating SMURF1-C/EBPβ-DKK1 Axis. Int J Mol Sci. 2020;21: pubmed publisher
  5. Pal A, Leung J, Ang G, Rao V, Pignata L, Lim H, et al. EHMT2 epigenetically suppresses Wnt signaling and is a potential target in embryonal rhabdomyosarcoma. elife. 2020;9: pubmed publisher
  6. Liu Q, Zhou C, Zhang B. Upregulation of musashi1 increases malignancy of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway and predicts a poor prognosis. BMC Gastroenterol. 2019;19:230 pubmed publisher
  7. Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed publisher
  8. Lu C, Liao Z, Cai M, Zhang G. MicroRNA-320a downregulation mediates human liver cancer cell proliferation through the Wnt/?-catenin signaling pathway. Oncol Lett. 2017;13:573-578 pubmed publisher
  9. Hu P, Chu J, Wu Y, Sun L, Lv X, Zhu Y, et al. NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2. Oncotarget. 2015;6:32410-25 pubmed publisher
  10. Shinojima N, Nakamura H, Tasaki M, Kameno K, Anai S, Iyama K, et al. A patient with medulloblastoma in its early developmental stage. J Neurosurg Pediatr. 2014;14:615-20 pubmed publisher