This is a Validated Antibody Database (VAD) review about human DGCR8, based on 8 published articles (read how Labome selects the articles), using DGCR8 antibody in all methods. It is aimed to help Labome visitors find the most suited DGCR8 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DGCR8 synonym: C22orf12; DGCRK6; Gy1; pasha; microprocessor complex subunit DGCR8; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8

Abcam
rabbit polyclonal
  • western blot; human; 1:1000; fig s11
Abcam DGCR8 antibody (Abcam, ab90579) was used in western blot on human samples at 1:1000 (fig s11). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
Abcam DGCR8 antibody (Abcam, ab90579) was used in western blot on human samples at 1:2000. Blood Cancer J (2013) ncbi
rabbit polyclonal
  • western blot; human
Abcam DGCR8 antibody (Abcam, ab90579) was used in western blot on human samples . Mol Neurobiol (2013) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Abcam DGCR8 antibody (Abcam, ab90579) was used in western blot on human samples at 1:1000. J Biol Chem (2013) ncbi
rabbit polyclonal
  • western blot; human
Abcam DGCR8 antibody (Abcam, ab90579) was used in western blot on human samples . EMBO J (2012) ncbi
Bethyl
rabbit polyclonal
  • RNA immunoprecipitation; human
  • immunocytochemistry; human; 2 ug/ml
In order to develop reagents to study RNA binding proteins, Bethyl DGCR8 antibody (Bethyl, A302-468A) was used in RNA immunoprecipitation on human samples and in immunocytochemistry on human samples at 2 ug/ml. Mol Cell (2016) ncbi
Proteintech Group
mouse monoclonal (4D11A3)
  • immunoprecipitation; mouse; fig 1
  • western blot; mouse; 1:1000; fig 1
  • immunoprecipitation; human; fig 1
  • western blot; human; 1:1000; fig 1
Proteintech Group DGCR8 antibody (Protein Tech Group, 60084-1-Ig) was used in immunoprecipitation on mouse samples (fig 1), in western blot on mouse samples at 1:1000 (fig 1), in immunoprecipitation on human samples (fig 1) and in western blot on human samples at 1:1000 (fig 1). Nucleic Acids Res (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D78E4)
  • chromatin immunoprecipitation; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology DGCR8 antibody (CST, 6914) was used in chromatin immunoprecipitation on human samples (fig 3a) and in western blot on human samples (fig 1b). Biochim Biophys Acta (2017) ncbi
Articles Reviewed
  1. Patne K, Rakesh R, Arya V, Chanana U, Sethy R, Swer P, et al. BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage. Biochim Biophys Acta. 2017;1860:936-951 pubmed publisher
  2. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  3. Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, et al. SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic Acids Res. 2015;43:7945-60 pubmed publisher
  4. Bahn J, Ahn J, Lin X, Zhang Q, Lee J, Civelek M, et al. Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways. Nat Commun. 2015;6:6355 pubmed publisher
  5. Caramuta S, Lee L, Ozata D, Akçakaya P, Georgii Hemming P, Xie H, et al. Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma. Blood Cancer J. 2013;3:e152 pubmed publisher
  6. Di Carlo V, Grossi E, Laneve P, Morlando M, Dini Modigliani S, Ballarino M, et al. TDP-43 regulates the microprocessor complex activity during in vitro neuronal differentiation. Mol Neurobiol. 2013;48:952-63 pubmed publisher
  7. Narayanan A, Iordanskiy S, Das R, Van Duyne R, Santos S, Jaworski E, et al. Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA. J Biol Chem. 2013;288:20014-33 pubmed publisher
  8. Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J. 2012;31:4502-10 pubmed publisher