This is a Validated Antibody Database (VAD) review about human DFF45, based on 5 published articles (read how Labome selects the articles), using DFF45 antibody in all methods. It is aimed to help Labome visitors find the most suited DFF45 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DFF45 synonym: DFF-45; DFF1; ICAD; DNA fragmentation factor subunit alpha; DFF45; DNA fragmentation factor 45 kDa subunit; DNA fragmentation factor, 45kDa, alpha polypeptide; inhibitor of CAD

Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
In order to elucidate the upstream mechanisms of apoptosis triggered by an anti-microtubule drug, ABT-751, Cell Signaling Technology DFF45 antibody (cell signalling, 9731) was used in western blot on human samples at 1:1000 (fig 5a). Toxicol Appl Pharmacol (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to elucidate inhibition of BCL-W and BCL-XL by directed elimination of senescent cells, Cell Signaling Technology DFF45 antibody (Cell Signaling, 9731) was used in western blot on human samples (fig 1). Nat Commun (2016) ncbi
EMD Millipore
rabbit polyclonal
  • immunoprecipitation; human
EMD Millipore DFF45 antibody (Millipore, AB16961) was used in immunoprecipitation on human samples . Biochim Biophys Acta (2014) ncbi
MBL International
mouse monoclonal (6B8)
  • western blot; human; 1:500; loading ...; fig 2a
MBL International DFF45 antibody (MBL International, M037-3) was used in western blot on human samples at 1:500 (fig 2a). Cell Death Dis (2017) ncbi
BD Biosciences
mouse monoclonal (19/DFF45)
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, BD Biosciences DFF45 antibody (Transduction Laboratories, D76320 (BD #611036)) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
Articles Reviewed
  1. Miles M, Hawkins C. Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine. Cell Death Dis. 2017;8:e3062 pubmed publisher
  2. Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
  3. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  4. Yosef R, Pilpel N, Tokarsky Amiel R, Biran A, Ovadya Y, Cohen S, et al. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL. Nat Commun. 2016;7:11190 pubmed publisher
  5. Johnson B, Opimba M, Bernier J. Implications of the O-GlcNAc modification in the regulation of nuclear apoptosis in T cells. Biochim Biophys Acta. 2014;1840:191-8 pubmed publisher