This is a Validated Antibody Database (VAD) review about human DCAF7, based on 3 published articles (read how Labome selects the articles), using DCAF7 antibody in all methods. It is aimed to help Labome visitors find the most suited DCAF7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
DCAF7 synonym: AN11; HAN11; SWAN-1; WDR68; DDB1- and CUL4-associated factor 7; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; human anthocyanin; seven-WD-repeat protein of the AN11 family-1

Knockout validation
Abcam
rabbit monoclonal (EPR8712)
  • western blot knockout validation; human; loading ...; fig 1h
  • western blot knockout validation; mouse; loading ...; fig 4a
  • immunoprecipitation; mouse; loading ...; fig 4d
Abcam DCAF7 antibody (Abcam, ab138490) was used in western blot knockout validation on human samples (fig 1h), in western blot knockout validation on mouse samples (fig 4a) and in immunoprecipitation on mouse samples (fig 4d). Nucleic Acids Res (2019) ncbi
Abcam
rabbit monoclonal (EPR8712)
  • western blot knockout validation; human; loading ...; fig 1h
  • western blot knockout validation; mouse; loading ...; fig 4a
  • immunoprecipitation; mouse; loading ...; fig 4d
Abcam DCAF7 antibody (Abcam, ab138490) was used in western blot knockout validation on human samples (fig 1h), in western blot knockout validation on mouse samples (fig 4a) and in immunoprecipitation on mouse samples (fig 4d). Nucleic Acids Res (2019) ncbi
rabbit monoclonal (EPR8712)
  • western blot; human; loading ...; fig 3c
In order to investigate the mechanism of induction of metabolic syndrome by RK1B missense mutations, Abcam DCAF7 antibody (Abcam, ab138490) was used in western blot on human samples (fig 3c). Sci Rep (2017) ncbi
rabbit monoclonal (EPR8712)
  • immunocytochemistry; human; 1:2000; loading ...; fig s6a
  • immunocytochemistry; mouse; 1:2000; loading ...; fig s6b
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 2f
  • western blot; mouse; 1:1000; loading ...; fig 2c
In order to study the interaction between Hap1 and Dcaf7, Abcam DCAF7 antibody (Abcam, EPR8712) was used in immunocytochemistry on human samples at 1:2000 (fig s6a), in immunocytochemistry on mouse samples at 1:2000 (fig s6b), in immunohistochemistry on mouse samples at 1:2000 (fig 2f) and in western blot on mouse samples at 1:1000 (fig 2c). Proc Natl Acad Sci U S A (2017) ncbi
Articles Reviewed
  1. Yu D, Cattoglio C, Xue Y, Zhou Q. A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis. Nucleic Acids Res. 2019;47:4462-4475 pubmed publisher
  2. Abu Jhaisha S, Widowati E, Kii I, Sonamoto R, Knapp S, Papadopoulos C, et al. DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain. Sci Rep. 2017;7:6420 pubmed publisher
  3. Xiang J, Yang S, Xin N, Gaertig M, Reeves R, Li S, et al. DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome. Proc Natl Acad Sci U S A. 2017;114:E1224-E1233 pubmed publisher