This is a Validated Antibody Database (VAD) review about human CypA, based on 14 published articles (read how Labome selects the articles), using CypA antibody in all methods. It is aimed to help Labome visitors find the most suited CypA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CypA synonym: CYPA; CYPH; HEL-S-69p; peptidyl-prolyl cis-trans isomerase A; PPIase A; T cell cyclophilin; cyclosporin A-binding protein; epididymis secretory sperm binding protein Li 69p; peptidylprolyl isomerase A (cyclophilin A); rotamase A

Abcam
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 1s1a
Abcam CypA antibody (AbCam, ab58144) was used in western blot on human samples at 1:1000 (fig 1s1a). elife (2019) ncbi
mouse monoclonal
  • western blot; human; 1:250; loading ...; fig 1d
Abcam CypA antibody (Abcam, ab58144) was used in western blot on human samples at 1:250 (fig 1d). Int J Obes (Lond) (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
In order to characterize the P2X7R-secretome in M1 and M2 macrophages., Abcam CypA antibody (Abcam, ab41684) was used in western blot on mouse samples (fig 2a). Sci Rep (2016) ncbi
mouse monoclonal
  • western blot; mouse; 1:1000; loading ...; fig 2
In order to present nuclear rna isolation and sequencing, Abcam CypA antibody (Abcam, ab58144) was used in western blot on mouse samples at 1:1000 (fig 2). Methods Mol Biol (2016) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig s6h
Abcam CypA antibody (Abcam, ab41684) was used in western blot on rat samples at 1:1000 (fig s6h). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam CypA antibody (Abcam, ab41684) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Abcam CypA antibody (Abcam, Ab3563) was used in western blot on human samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100
Abcam CypA antibody (Abcam, ab41684) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. PLoS ONE (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; fig 8
In order to assess mediation of the nuclear import of HIV-1 during infection by cooperation between Nup358 and KIF5B, Invitrogen CypA antibody (ThermoScientific, PA1-025) was used in western blot on human samples (fig 8). PLoS Pathog (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 8
In order to study multimodal inhibition of HIV-1 by PF74 and the roles of capsid-interacting host factors, Invitrogen CypA antibody (ThermoFisher, PA1-025) was used in western blot on human samples (fig 8). J Virol (2016) ncbi
R&D Systems
goat polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 1
In order to study the inhibition of extracellular CyPA in a mouse model of troponin I-induced autoimmune myocarditis, R&D Systems CypA antibody (R&D Systems, AF3589) was used in immunohistochemistry - paraffin section on mouse samples (fig 1). PLoS ONE (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 1i
Cell Signaling Technology CypA antibody (Cell Signaling, 2175) was used in western blot on human samples at 1:2000 (fig 1i). Nat Commun (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig s2b
Cell Signaling Technology CypA antibody (Cell Signaling Technology, 2175) was used in western blot on mouse samples at 1:5000 (fig s2b). Cancer Discov (2017) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology CypA antibody (Cell Signaling Technology, 2175S) was used in western blot on human samples . Cell Res (2014) ncbi
Articles Reviewed
  1. Gaska J, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. elife. 2019;8: pubmed publisher
  2. Sheng C, Yao C, Wang Z, Chen H, Zhao Y, Xu D, et al. Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing. Nat Commun. 2018;9:4381 pubmed publisher
  3. Haricharan S, Punturi N, Singh P, Holloway K, Anurag M, Schmelz J, et al. Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discov. 2017;7:1168-1183 pubmed publisher
  4. Hirschmugl B, Desoye G, Catalano P, Klymiuk I, Scharnagl H, Payr S, et al. Maternal obesity modulates intracellular lipid turnover in the human term placenta. Int J Obes (Lond). 2017;41:317-323 pubmed publisher
  5. Dharan A, Talley S, Tripathi A, Mamede J, Majetschak M, Hope T, et al. KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection. PLoS Pathog. 2016;12:e1005700 pubmed publisher
  6. Saito A, Ferhadian D, Sowd G, Serrao E, Shi J, Halambage U, et al. Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74. J Virol. 2016;90:5808-5823 pubmed publisher
  7. de Torre Minguela C, Barberà Cremades M, Gómez A, Martín Sánchez F, Pelegrín P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep. 2016;6:22586 pubmed publisher
  8. Dhaliwal N, Mitchell J. Nuclear RNA Isolation and Sequencing. Methods Mol Biol. 2016;1402:63-71 pubmed publisher
  9. Schafer S, Adami E, Heinig M, Rodrigues K, Kreuchwig F, Silhavy J, et al. Translational regulation shapes the molecular landscape of complex disease phenotypes. Nat Commun. 2015;6:7200 pubmed publisher
  10. Heinzmann D, Bangert A, Müller A, von Ungern Sternberg S, Emschermann F, Schönberger T, et al. The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis. PLoS ONE. 2015;10:e0124606 pubmed publisher
  11. Schutkowski A, Wege N, Stangl G, König B. Tissue-specific expression of monocarboxylate transporters during fasting in mice. PLoS ONE. 2014;9:e112118 pubmed publisher
  12. Fan Y, Meley D, Pizer B, Sée V. Mir-34a mimics are potential therapeutic agents for p53-mutated and chemo-resistant brain tumour cells. PLoS ONE. 2014;9:e108514 pubmed publisher
  13. Kim H, Al Mahrouki A, Gorjizadeh A, Sadeghi Naini A, Karshafian R, Czarnota G. Quantitative ultrasound characterization of tumor cell death: ultrasound-stimulated microbubbles for radiation enhancement. PLoS ONE. 2014;9:e102343 pubmed publisher
  14. Feng Q, Zhang Z, Shea M, Creighton C, Coarfa C, Hilsenbeck S, et al. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014;24:809-19 pubmed publisher