This is a Validated Antibody Database (VAD) review about human Cyp2e1, based on 13 published articles (read how Labome selects the articles), using Cyp2e1 antibody in all methods. It is aimed to help Labome visitors find the most suited Cyp2e1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cyp2e1 synonym: CPE1; CYP2E; P450-J; P450C2E; cytochrome P450 2E1; 4-nitrophenol 2-hydroxylase; CYPIIE1; cytochrome P450, family 2, subfamily E, polypeptide 1; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; cytochrome P450-J; flavoprotein-linked monooxygenase; microsomal monooxygenase; xenobiotic monooxygenase

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; rat; 1:1000; fig 4b
Abcam Cyp2e1 antibody (Abcam, ab84598) was used in western blot knockout validation on rat samples at 1:1000 (fig 4b). Biochem Pharmacol (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig 3a
Abcam Cyp2e1 antibody (Abcam, ab28146) was used in western blot on mouse samples at 1:5000 (fig 3a). Toxicol Sci (2018) ncbi
rabbit polyclonal
  • western blot knockout validation; rat; 1:1000; fig 4b
Abcam Cyp2e1 antibody (Abcam, ab84598) was used in western blot knockout validation on rat samples at 1:1000 (fig 4b). Biochem Pharmacol (2016) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; loading ...; fig s2d
EMD Millipore Cyp2e1 antibody (Millipore, AB1252) was used in western blot on mouse samples (fig s2d). J Clin Invest (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:750; fig 3
EMD Millipore Cyp2e1 antibody (Millipore, 1252) was used in immunohistochemistry - paraffin section on mouse samples at 1:750 (fig 3). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3
In order to study the effects of proteasomal inhibition on drug-induced liver injury, EMD Millipore Cyp2e1 antibody (Millipore, AB1252) was used in western blot on mouse samples (fig 3). Int J Mol Med (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig s6
In order to study postnatal liver maturation and its support by ESRP2 and adult splicing program in hepatocytes, EMD Millipore Cyp2e1 antibody (Millipore, AB1252) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s6). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 2b, 3d
EMD Millipore Cyp2e1 antibody (Merck Millipore, AB1252) was used in western blot on mouse samples (fig 2b, 3d). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:1000
EMD Millipore Cyp2e1 antibody (Millipore, AB1252) was used in western blot on rat samples at 1:1000. Toxicol In Vitro (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study the co-culture of mesenchymal stem cells with liver cells in bioartificial liver system, EMD Millipore Cyp2e1 antibody (Chemicon, AB1252) was used in western blot on human samples . Biotechnol Bioeng (2013) ncbi
Sigma-Aldrich
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2b
  • western blot; mouse; 1:1000; loading ...; fig 2a
Sigma-Aldrich Cyp2e1 antibody (Sigma, HPA009128) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2b) and in western blot on mouse samples at 1:1000 (fig 2a). Cancer Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2b
  • western blot; mouse; 1:1000; loading ...; fig 2a
Sigma-Aldrich Cyp2e1 antibody (Sigma, HPA009128) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2b) and in western blot on mouse samples at 1:1000 (fig 2a). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal
  • immunocytochemistry; human; 1:200; fig 5
Sigma-Aldrich Cyp2e1 antibody (Sigma, SAB1405688) was used in immunocytochemistry on human samples at 1:200 (fig 5). Exp Biol Med (Maywood) (2017) ncbi
mouse monoclonal
  • western blot; hamsters; loading ...; fig 3a
Sigma-Aldrich Cyp2e1 antibody (Sigma-Aldrich, SAB1405688) was used in western blot on hamsters samples (fig 3a). Mutagenesis (2016) ncbi
Articles Reviewed
  1. Luo Y, Furuya S, Soldatov V, Kosyk O, Yoo H, Fukushima H, et al. Metabolism and Toxicity of Trichloroethylene and Tetrachloroethylene in Cytochrome P450 2E1 Knockout and Humanized Transgenic Mice. Toxicol Sci. 2018;164:489-500 pubmed publisher
  2. Ngo H, Kim D, Cha Y, Na H, Surh Y. Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis. Cancer Res. 2017;77:4797-4808 pubmed publisher
  3. Yang A, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, et al. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017;127:2829-2841 pubmed publisher
  4. Hadden W, Young J, Holle A, McFetridge M, Kim D, Wijesinghe P, et al. Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proc Natl Acad Sci U S A. 2017;114:5647-5652 pubmed publisher
  5. Lee Montiel F, George S, Gough A, Sharma A, Wu J, DeBiasio R, et al. Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems. Exp Biol Med (Maywood). 2017;242:1617-1632 pubmed publisher
  6. Huffman M, Høie A, Svendsen C, Brunborg G, Murkovic M, Glatt H, et al. An in vitro study on the genotoxic effect of substituted furans in cells transfected with human metabolizing enzymes: 2,5-dimethylfuran and furfuryl alcohol. Mutagenesis. 2016;31:597-602 pubmed publisher
  7. Shearn C, Orlicky D, McCullough R, Jiang H, Maclean K, Mercer K, et al. Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS ONE. 2016;11:e0154152 pubmed publisher
  8. Wang X, Tang Y, Lu J, Shao Y, Qin X, Li Y, et al. Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9. Biochem Pharmacol. 2016;105:80-90 pubmed publisher
  9. Park W, Kim S, Kim Y, Park J. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription. Int J Mol Med. 2016;37:613-22 pubmed publisher
  10. Bhate A, Parker D, Bebee T, Ahn J, Arif W, Rashan E, et al. ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nat Commun. 2015;6:8768 pubmed publisher
  11. Yi H, Eun H, Lee Y, Jung J, Park S, Park K, et al. Treatment with 4-methylpyrazole modulated stellate cells and natural killer cells and ameliorated liver fibrosis in mice. PLoS ONE. 2015;10:e0127946 pubmed publisher
  12. Vichi S, Sandström von Tobel J, Gemma S, Stanzel S, Kopp Schneider A, Monnet Tschudi F, et al. Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures. Toxicol In Vitro. 2015;30:176-84 pubmed publisher
  13. Yang Y, Li J, Pan X, Zhou P, Yu X, Cao H, et al. Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system. Biotechnol Bioeng. 2013;110:958-68 pubmed publisher