This is a Validated Antibody Database (VAD) review about human CrkL, based on 16 published articles (read how Labome selects the articles), using CrkL antibody in all methods. It is aimed to help Labome visitors find the most suited CrkL antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Invitrogen
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1c
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
  • immunocytochemistry; mouse; loading ...; fig 3c
Invitrogen CrkL antibody (Thermo Fisher Scientific, PA5-28622) was used in western blot knockout validation on human samples (fig 4a), in immunoprecipitation on human samples (fig 1c), in immunocytochemistry on human samples at 1:100 (fig 2e) and in immunocytochemistry on mouse samples (fig 3c). mSphere (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • western blot; human; 1:1000; loading ...; fig e9b
Santa Cruz Biotechnology CrkL antibody (Santa Cruz, sc-365092) was used in western blot on human samples at 1:1000 (fig e9b). Nature (2022) ncbi
mouse monoclonal (B-1)
  • immunohistochemistry - frozen section; mouse; fig 2a
Santa Cruz Biotechnology CrkL antibody (Santa Cruz Biotechnology, sc-365092) was used in immunohistochemistry - frozen section on mouse samples (fig 2a). Nature (2021) ncbi
mouse monoclonal (A-1)
  • western blot; mouse; fig 5
Santa Cruz Biotechnology CrkL antibody (santa Cruz, sc-365471) was used in western blot on mouse samples (fig 5). Mol Syst Biol (2016) ncbi
mouse monoclonal (B-1)
  • western blot; human; fig 7
Santa Cruz Biotechnology CrkL antibody (Santa Cruz, sc-365092) was used in western blot on human samples (fig 7). EMBO J (2015) ncbi
Abcam
domestic rabbit monoclonal (EP270Y)
  • western blot; mouse
  • western blot; human
Abcam CrkL antibody (Abcam, ab52908) was used in western blot on mouse samples and in western blot on human samples . Oncotarget (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot knockout validation; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 1c
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
  • immunocytochemistry; mouse; loading ...; fig 3c
Invitrogen CrkL antibody (Thermo Fisher Scientific, PA5-28622) was used in western blot knockout validation on human samples (fig 4a), in immunoprecipitation on human samples (fig 1c), in immunocytochemistry on human samples at 1:100 (fig 2e) and in immunocytochemistry on mouse samples (fig 3c). mSphere (2017) ncbi
Cell Signaling Technology
mouse monoclonal (32H4)
  • western blot; human; 1:1000; loading ...; fig e2d
Cell Signaling Technology CrkL antibody (Cell Signaling, 3182S) was used in western blot on human samples at 1:1000 (fig e2d). Nature (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5d
  • immunohistochemistry - paraffin section; human; loading ...; fig 5f
  • western blot; human; loading ...; fig s4c
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181) was used in western blot on mouse samples (fig 5d), in immunohistochemistry - paraffin section on human samples (fig 5f) and in western blot on human samples (fig s4c). Angiogenesis (2021) ncbi
mouse monoclonal (32H4)
  • western blot; human; loading ...; fig s4c
Cell Signaling Technology CrkL antibody (Cell Signaling, 3182) was used in western blot on human samples (fig s4c). Angiogenesis (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1b
Cell Signaling Technology CrkL antibody (Cell Signaling Technology, 3181) was used in western blot on human samples at 1:1000 (fig 1b). Nat Commun (2021) ncbi
mouse monoclonal (32H4)
  • western blot; human; 1:1000; loading ...; fig 1f
Cell Signaling Technology CrkL antibody (Cell Signaling Technology, 3182) was used in western blot on human samples at 1:1000 (fig 1f). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4f
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181L) was used in western blot on human samples (fig 4f). Cell Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181) was used in western blot on human samples (fig 1d). Biochemistry (2018) ncbi
mouse monoclonal (32H4)
  • western blot; human; loading ...; fig s2
Cell Signaling Technology CrkL antibody (Cell Signaling, 3182) was used in western blot on human samples (fig s2). Stem Cells Dev (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181) was used in western blot on human samples (fig 1b). Int J Nanomedicine (2016) ncbi
mouse monoclonal (32H4)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology CrkL antibody (Cell Signaling, 3182) was used in western blot on human samples (fig 1b). Int J Nanomedicine (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology CrkL antibody (Cell Technologies, 3181) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (32H4)
  • western blot; human; fig 4
Cell Signaling Technology CrkL antibody (Cell Technologies, 3182) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human
Cell Signaling Technology CrkL antibody (Cell Signaling, 3181) was used in western blot on human samples . Autophagy (2016) ncbi
mouse monoclonal (32H4)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology CrkL antibody (Cell signaling, 3182) was used in western blot on human samples (fig 4b). Int J Cancer (2015) ncbi
Articles Reviewed
  1. Weiss J, Hunter M, CRUZ N, Baggiolini A, Tagore M, Ma Y, et al. Anatomic position determines oncogenic specificity in melanoma. Nature. 2022;604:354-361 pubmed publisher
  2. Oury J, Zhang W, Leloup N, Koide A, Corrado A, Ketavarapu G, et al. Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia. Nature. 2021;595:404-408 pubmed publisher
  3. Amado Azevedo J, van Stalborch A, Valent E, Nawaz K, van Bezu J, Eringa E, et al. Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation. Angiogenesis. 2021;: pubmed publisher
  4. Lei H, Xu H, Shan H, Liu M, Lu Y, Fang Z, et al. Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia. Nat Commun. 2021;12:51 pubmed publisher
  5. Hoj J, Mayro B, Pendergast A. A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Cell Rep. 2019;29:3421-3434.e8 pubmed publisher
  6. Wang Z, Kim M, Martinez Ferrando I, Koleske A, Pandey A, Cole P. Analysis of Cellular Tyrosine Phosphorylation via Chemical Rescue of Conditionally Active Abl Kinase. Biochemistry. 2018;57:1390-1398 pubmed publisher
  7. Carpenter V, Chen Y, Dolat L, Valdivia R. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017;2: pubmed publisher
  8. Chorzalska A, Kim J, Roder K, Tepper A, Ahsan N, Rao R, et al. Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017;26:656-677 pubmed publisher
  9. Shi D, Liu Y, Xi R, Zou W, Wu L, Zhang Z, et al. Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells. Int J Nanomedicine. 2016;11:5823-5835 pubmed
  10. Agatheeswaran S, Pattnayak N, Chakraborty S. Identification and functional characterization of the miRNA-gene regulatory network in chronic myeloid leukemia lineage negative cells. Sci Rep. 2016;6:32493 pubmed publisher
  11. Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
  12. Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed publisher
  13. Karvela M, Baquero P, Kuntz E, Mukhopadhyay A, Mitchell R, Allan E, et al. ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells. Autophagy. 2016;12:936-48 pubmed publisher
  14. Nasr R, Hmadi R, El Eit R, Iskandarani A, Jabbour M, Zaatari G, et al. ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model. Int J Cancer. 2015;137:698-709 pubmed publisher
  15. Gill M, Turner R, Stevenson P, Way M. KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction. EMBO J. 2015;34:448-65 pubmed publisher
  16. Frietsch J, Kastner C, Grunewald T, Schweigel H, Nollau P, Ziermann J, et al. LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia. Oncotarget. 2014;5:5257-71 pubmed