This is a Validated Antibody Database (VAD) review about human Cdc2, based on 126 published articles (read how Labome selects the articles), using Cdc2 antibody in all methods. It is aimed to help Labome visitors find the most suited Cdc2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cdc2 synonym: CDC2; CDC28A; P34CDC2

Knockout validation
Abcam
mouse monoclonal (A17)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1c
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1c). PLoS Genet (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (17)
  • western blot knockout validation; mouse; fig 2
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot knockout validation on mouse samples (fig 2). Proc Natl Acad Sci U S A (2012) ncbi
Abcam
domestic rabbit monoclonal (EPR165)
  • western blot; human; 1:10,000; loading ...; fig 5a, 5b
Abcam Cdc2 antibody (Abcam, ab133327) was used in western blot on human samples at 1:10,000 (fig 5a, 5b). Biol Proced Online (2022) ncbi
domestic rabbit monoclonal (EPR165)
  • western blot; human; loading ...; fig 2f
Abcam Cdc2 antibody (abcam, ab133327) was used in western blot on human samples (fig 2f). Mol Cancer (2021) ncbi
domestic rabbit monoclonal (YE324)
  • western blot; human; loading ...; fig 3j
Abcam Cdc2 antibody (Abcam, ab32094) was used in western blot on human samples (fig 3j). Clin Transl Med (2021) ncbi
mouse monoclonal (A17)
  • immunohistochemistry; mouse; 1:100; fig 5a
Abcam Cdc2 antibody (Abcam, ab18) was used in immunohistochemistry on mouse samples at 1:100 (fig 5a). J Cell Sci (2021) ncbi
domestic rabbit monoclonal (EPR165)
  • western blot; human; loading ...; fig 3i
Abcam Cdc2 antibody (Abcam, ab133327) was used in western blot on human samples (fig 3i). Aging (Albany NY) (2021) ncbi
mouse monoclonal (A17)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1c
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1c). PLoS Genet (2020) ncbi
domestic rabbit monoclonal (YE324)
  • western blot; human; 1:2000; loading ...; fig 3c
Abcam Cdc2 antibody (Abcam, ab32094) was used in western blot on human samples at 1:2000 (fig 3c). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (EPR165)
  • immunohistochemistry; human; 1:250; loading ...; fig 6d
  • western blot; human; 1:1000; loading ...; fig 2g
Abcam Cdc2 antibody (Abcam, ab133327) was used in immunohistochemistry on human samples at 1:250 (fig 6d) and in western blot on human samples at 1:1000 (fig 2g). Nat Commun (2020) ncbi
mouse monoclonal (A17)
  • western blot; rat; fig 3d
Abcam Cdc2 antibody (Abcam, ab180715) was used in western blot on rat samples (fig 3d). J Cachexia Sarcopenia Muscle (2020) ncbi
mouse monoclonal (A17)
  • western blot; human; loading ...; fig 4i
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on human samples (fig 4i). Sci Adv (2020) ncbi
mouse monoclonal (A17)
  • western blot; human; 1:3000; loading ...; fig 3b
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on human samples at 1:3000 (fig 3b). Med Sci Monit (2019) ncbi
domestic rabbit monoclonal (EPR165)
  • immunocytochemistry; human; loading ...; fig s5b
  • western blot; human; loading ...; fig s5c
Abcam Cdc2 antibody (Abcam, ab133327) was used in immunocytochemistry on human samples (fig s5b) and in western blot on human samples (fig s5c). Science (2019) ncbi
monoclonal (A17)
  • immunocytochemistry; mouse; loading ...; fig 4b
Abcam Cdc2 antibody (Abcam, ab203852) was used in immunocytochemistry on mouse samples (fig 4b). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (EPR7875)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s1h
Abcam Cdc2 antibody (Abcam, EPR7875) was used in immunocytochemistry on mouse samples at 1:100 (fig s1h). Sci Rep (2019) ncbi
mouse monoclonal (A17)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s1i
Abcam Cdc2 antibody (Abcam, A17) was used in immunocytochemistry on mouse samples at 1:100 (fig s1i). Sci Rep (2019) ncbi
domestic rabbit monoclonal (EPR7875)
  • immunohistochemistry - paraffin section; human; loading ...; fig 7b
Abcam Cdc2 antibody (Abcam, ab133463) was used in immunohistochemistry - paraffin section on human samples (fig 7b). Cells (2019) ncbi
mouse monoclonal (A17)
  • western blot; human; loading ...; fig 2c
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on human samples (fig 2c). DNA Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Abcam Cdc2 antibody (Abcam, ab47594) was used in western blot on human samples (fig 2c). DNA Cell Biol (2016) ncbi
mouse monoclonal (A17)
  • western blot; mouse; fig 1
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on mouse samples (fig 1). Cell Rep (2016) ncbi
domestic rabbit monoclonal (YE324)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
Abcam Cdc2 antibody (Abcam, ab32094) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Arch Gynecol Obstet (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 6
Abcam Cdc2 antibody (Abcam, ab47594) was used in western blot on human samples (fig 6). BMC Cancer (2016) ncbi
mouse monoclonal (A17)
  • western blot; human; loading ...; fig 6b
Abcam Cdc2 antibody (Abcam, Ab18) was used in western blot on human samples (fig 6b). Oncol Rep (2016) ncbi
mouse monoclonal (Y100.4)
  • immunoprecipitation; fission yeast; fig 3
Abcam Cdc2 antibody (ABCAM, ab5467) was used in immunoprecipitation on fission yeast samples (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (Y100.4)
  • western blot; fission yeast; fig 3a
Abcam Cdc2 antibody (Abcam, ab5467) was used in western blot on fission yeast samples (fig 3a). Nucleic Acids Res (2015) ncbi
mouse monoclonal (A17)
  • western blot; human
Abcam Cdc2 antibody (Abcam, Ab18) was used in western blot on human samples . J Virol (2015) ncbi
mouse monoclonal (Y100.4)
  • western blot; fission yeast; 1:1000; loading ...
Abcam Cdc2 antibody (Abcam, ab5467) was used in western blot on fission yeast samples at 1:1000. Methods Mol Biol (2014) ncbi
mouse monoclonal (A17)
  • western blot; human; 1:1,000
In order to report on the development and characterization of a human pancreatic beta-cell line that is conditionally immortalized, Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on human samples at 1:1,000. J Clin Invest (2014) ncbi
mouse monoclonal (A17)
  • immunocytochemistry; human; loading ...; fig 6a
Abcam Cdc2 antibody (Abcam, ab18) was used in immunocytochemistry on human samples (fig 6a). elife (2014) ncbi
mouse monoclonal (A17)
  • western blot; human; 1:1000
Abcam Cdc2 antibody (Abcam, ab18) was used in western blot on human samples at 1:1000. J Biol Chem (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (17)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-54) was used in western blot on human samples (fig 4a). BMC Cancer (2022) ncbi
mouse monoclonal (pY15.44)
  • western blot; human; loading ...; fig 1s1e, 3g, 4d
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-136014) was used in western blot on human samples (fig 1s1e, 3g, 4d). elife (2020) ncbi
mouse monoclonal (17)
  • immunoprecipitation; human; loading ...; fig 3a
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54AC) was used in immunoprecipitation on human samples (fig 3a). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (17)
  • western blot; human; fig 6d
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on human samples (fig 6d). Nat Commun (2017) ncbi
mouse monoclonal (17)
  • western blot; human; 1:300; loading ...; fig s4j
In order to identify XBP1-u as a regulator of the MDM2/p53 function, Santa Cruz Biotechnology Cdc2 antibody (SantaCruz, sc-54) was used in western blot on human samples at 1:300 (fig s4j). Sci Adv (2017) ncbi
mouse monoclonal (17)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology Cdc2 antibody (santa, 17) was used in western blot on human samples (fig 2a). Oncogene (2017) ncbi
mouse monoclonal (AN21.2)
  • western blot; mouse; fig s3
In order to explore the role of Fancd2 in normal development and tumorigenesis, Santa Cruz Biotechnology Cdc2 antibody (santa cruz, sc-53219) was used in western blot on mouse samples (fig s3). Sci Rep (2017) ncbi
mouse monoclonal (Y100.4)
  • western blot; fission yeast; fig 3f
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, Y100.4) was used in western blot on fission yeast samples (fig 3f). Nature (2017) ncbi
mouse monoclonal (17)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig st5
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig st5
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig st5
In order to outline the protocols for antibodies used for immunohistochemical studies, Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig st5), in immunohistochemistry - paraffin section on rat samples at 1:1000 (fig st5) and in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig st5). J Toxicol Pathol (2017) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; 1:200; loading ...; fig 5a
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-53219) was used in western blot on human samples at 1:200 (fig 5a). Oncotarget (2017) ncbi
mouse monoclonal (B-5)
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-137035) was used in western blot on human samples at 1:1000 (fig 4a). Exp Ther Med (2016) ncbi
mouse monoclonal (B-5)
  • immunoprecipitation; human; 1:1000; loading ...; fig 2e
  • western blot; human; 1:1000; loading ...; fig 2a,2b,2c
  • western blot; mouse; 1:1000; loading ...; fig 6e
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-137035) was used in immunoprecipitation on human samples at 1:1000 (fig 2e), in western blot on human samples at 1:1000 (fig 2a,2b,2c) and in western blot on mouse samples at 1:1000 (fig 6e). Nat Commun (2017) ncbi
mouse monoclonal (17)
  • western blot; mouse; loading ...; fig 6a
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on mouse samples (fig 6a). Nat Commun (2016) ncbi
mouse monoclonal (17)
  • western blot; human; 1:500; loading ...; fig 2c
In order to elucidate the upstream mechanisms of apoptosis triggered by an anti-microtubule drug, ABT-751, Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-54) was used in western blot on human samples at 1:500 (fig 2c). Toxicol Appl Pharmacol (2016) ncbi
mouse monoclonal (F-10)
  • western blot; human; fig 3
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-166135) was used in western blot on human samples (fig 3). PLoS ONE (2016) ncbi
mouse monoclonal (POH-1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cdc2 antibody (SCBT, POH1) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (17)
  • western blot; human; 1:750; fig 4
Santa Cruz Biotechnology Cdc2 antibody ((Santa Cruz, SC-54) was used in western blot on human samples at 1:750 (fig 4). Cell Rep (2015) ncbi
mouse monoclonal (POH-1)
  • western blot; human; fig 4
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-51578) was used in western blot on human samples (fig 4). Oxid Med Cell Longev (2015) ncbi
mouse monoclonal (17)
  • western blot; human; fig 3
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on human samples (fig 3). BMC Cancer (2015) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; fig 4
Santa Cruz Biotechnology Cdc2 antibody (santa Cruz, sc-53219) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (17)
  • western blot; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, SC-54) was used in western blot on human samples . Toxicol Appl Pharmacol (2015) ncbi
mouse monoclonal (17)
  • western blot; human; 1:200; fig 1e
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on human samples at 1:200 (fig 1e). Oncotarget (2015) ncbi
mouse monoclonal (17)
  • immunohistochemistry - free floating section; guinea pig; 1:600; fig 3
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, SC-54) was used in immunohistochemistry - free floating section on guinea pig samples at 1:600 (fig 3). Neuroscience (2015) ncbi
mouse monoclonal (F-10)
  • immunohistochemistry; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-166135) was used in immunohistochemistry on human samples . BMC Cancer (2014) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; fig s2f
In order to study the effects of cyclin-dependent kinase 7 inhibitors on MYC proteins, Santa Cruz Biotechnology Cdc2 antibody (Santa, sc-53219) was used in western blot on human samples (fig s2f). Cell (2014) ncbi
mouse monoclonal (C-9)
  • western blot; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-137034) was used in western blot on human samples . Cancer Res (2014) ncbi
mouse monoclonal (17)
  • western blot; mouse
  • western blot; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, 17) was used in western blot on mouse samples and in western blot on human samples . Oncogene (2015) ncbi
mouse monoclonal (17)
  • western blot; human; 1:500
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on human samples at 1:500. Int J Biochem Cell Biol (2014) ncbi
mouse monoclonal (17)
  • western blot; mouse
In order to demonstrate a novel role for Poldip2 in regulating the cell cycle, Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal (17)
  • western blot; human; fig 2d
Santa Cruz Biotechnology Cdc2 antibody (Santa, sc-54) was used in western blot on human samples (fig 2d). J Biol Chem (2014) ncbi
mouse monoclonal (17)
  • western blot; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot on human samples . Mol Oncol (2014) ncbi
mouse monoclonal (17)
  • western blot; mouse
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-54) was used in western blot on mouse samples . Cell Cycle (2013) ncbi
mouse monoclonal (17)
  • western blot knockout validation; mouse; fig 2
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz, sc-54) was used in western blot knockout validation on mouse samples (fig 2). Proc Natl Acad Sci U S A (2012) ncbi
mouse monoclonal (17)
  • western blot; human
Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-54) was used in western blot on human samples . Am J Physiol Endocrinol Metab (2011) ncbi
mouse monoclonal (17)
  • western blot; mouse
In order to study the role in Cdk regulation of the novel gene magoh identified in a genetic screen of a murine cell cycle mutant, Santa Cruz Biotechnology Cdc2 antibody (Santa Cruz Biotechnology, sc-54) was used in western blot on mouse samples . Genes Cells (2011) ncbi
Invitrogen
domestic rabbit monoclonal (E.658.6)
  • immunocytochemistry; mouse; 1:50; loading ...; fig 5b
Invitrogen Cdc2 antibody (Thermo Fisher Scientific, MA5-15062) was used in immunocytochemistry on mouse samples at 1:50 (fig 5b). Biol Reprod (2018) ncbi
mouse monoclonal (A17.1.1)
  • western blot; human; 1:500; loading ...; fig 3a
In order to use polo-like kinase 1 inhibitors for a rationally designed chemotherapy protocols to treat patients with metastasized retinoblastoma, Invitrogen Cdc2 antibody (Milipore, MA5-11472) was used in western blot on human samples at 1:500 (fig 3a). Clin Exp Ophthalmol (2017) ncbi
mouse monoclonal (A17.1.1)
  • western blot; rat; fig 2
In order to characterize the thyroid carcinoma-associated PAX8-PPARG fusion protein and genomic binding and regulation of gene expression, Invitrogen Cdc2 antibody (thermofisher scientific, 11472) was used in western blot on rat samples (fig 2). Oncotarget (2015) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
In order to characterize modulation of microtubular structure and HSP90alpha chaperone activity against prostate cancer by 4-hydroxybenzoic acid derivatives as HDAC6-specific inhibitors, Invitrogen Cdc2 antibody (ThermoFisher Scientific, 44-686G) was used in western blot on human samples (fig 5). Biochem Pharmacol (2016) ncbi
mouse monoclonal (A17.1.1)
In order to identify the role of IFI27 in the cell proliferation of human epidermal keratinocytes, Invitrogen Cdc2 antibody (Thermo, MS-110-P1) was used . Cell Prolif (2015) ncbi
mouse monoclonal (A17.1.1)
  • immunoprecipitation; human; fig 1
In order to identify CDK4 binding partners, Invitrogen Cdc2 antibody (Lab Vision, A17.1) was used in immunoprecipitation on human samples (fig 1). Cell Cycle (2014) ncbi
mouse monoclonal (A17.1.1)
  • immunoprecipitation; mouse
  • western blot; mouse; 1:200; fig 3e
In order to elucidate the regulation of Notch by Cyclin C, Invitrogen Cdc2 antibody (Thermo, A17.1.1) was used in immunoprecipitation on mouse samples and in western blot on mouse samples at 1:200 (fig 3e). Nat Cell Biol (2014) ncbi
mouse monoclonal (A17.1.1)
  • immunohistochemistry - paraffin section; human; 1:500
In order to study the clinical manifestation of Alzheimer's disease involving cell-cycle regulation, neuronal death and repair of oxidative DNA damage, Invitrogen Cdc2 antibody (NeoMarkers, A17.1.1) was used in immunohistochemistry - paraffin section on human samples at 1:500. PLoS ONE (2014) ncbi
domestic rabbit polyclonal
In order to characterize new inhibitors of CDC25, Invitrogen Cdc2 antibody (Invitrogen, 44686G) was used . Mol Carcinog (2015) ncbi
mouse monoclonal (A17)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s2
In order to investigate the role of Mn superoxide dismutase in tissue regeneration using transgenic mice, Invitrogen Cdc2 antibody (Invitrogen, 33-1800) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s2). Free Radic Biol Med (2010) ncbi
Abnova
mouse monoclonal (1A4-1A9)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Abnova Cdc2 antibody (Abnova, 1A4-1A9) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
Cell Signaling Technology
mouse monoclonal (POH1)
  • western blot; human; 1:1000; loading ...; fig 4o, 4w
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples at 1:1000 (fig 4o, 4w). Nat Commun (2022) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples (fig 2c). Mol Ther Oncolytics (2022) ncbi
domestic rabbit monoclonal (10A11)
  • immunohistochemistry - frozen section; roundworm ; 1:100; loading ...; fig 6f
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in immunohistochemistry - frozen section on roundworm samples at 1:100 (fig 6f). Nucleic Acids Res (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; roundworm ; 1:500; loading ...; fig 5j
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111T) was used in immunohistochemistry - frozen section on roundworm samples at 1:500 (fig 5j). Nucleic Acids Res (2022) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig 1d
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples at 1:1000 (fig 1d). Cell Rep (2022) ncbi
mouse monoclonal (POH1)
  • western blot; human; 1:1000; loading ...; fig 7c
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technologies, 9116) was used in western blot on human samples at 1:1000 (fig 7c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig 7c
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technologies, 4539) was used in western blot on human samples at 1:1000 (fig 7c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in western blot on human samples at 1:1000 (fig 3b). Clin Transl Med (2021) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig s5c
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 10A11) was used in western blot on human samples at 1:1000 (fig s5c). Leukemia (2021) ncbi
mouse monoclonal (POH1)
  • western blot; human; fig 5c
Cell Signaling Technology Cdc2 antibody (CST, 9116S) was used in western blot on human samples (fig 5c). JCI Insight (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5c
Cell Signaling Technology Cdc2 antibody (CST, 9111) was used in western blot on human samples (fig 5c). JCI Insight (2021) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; loading ...; fig 1s1f
Cell Signaling Technology Cdc2 antibody (Cell signaling, 4539S) was used in western blot on human samples (fig 1s1f). elife (2020) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; dogs; 1:1000; fig 4c
Cell Signaling Technology Cdc2 antibody (CST, 4539) was used in western blot on dogs samples at 1:1000 (fig 4c). Cells (2020) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; axolotl; 1:1000; loading ...; fig 3s2b
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539S) was used in western blot on axolotl samples at 1:1000 (fig 3s2b). elife (2020) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig 3a, 3b, 3c
Cell Signaling Technology Cdc2 antibody (CST, 4539) was used in western blot on human samples at 1:1000 (fig 3a, 3b, 3c). Ther Adv Hematol (2020) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; loading ...; fig 6c
Cell Signaling Technology Cdc2 antibody (CST, 4539) was used in western blot on human samples at 1:1000 (fig 6c). Genes Cancer (2019) ncbi
mouse monoclonal (POH1)
  • western blot; human; 1:1000; loading ...; fig 2g
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 9116S) was used in western blot on human samples at 1:1000 (fig 2g). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; rat; fig 2b
  • western blot; human; 1:1500; loading ...; fig 2b
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in western blot on rat samples (fig 2b) and in western blot on human samples at 1:1500 (fig 2b). J Exp Clin Cancer Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on human samples (fig 4e). Cancer Cell Int (2019) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig 4e). Cancer Cell Int (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3c
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 9111) was used in western blot on human samples (fig 3c). Cells (2019) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; loading ...; fig 5c
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples (fig 5c). J Virol (2018) ncbi
domestic rabbit monoclonal (10A11)
  • immunocytochemistry; human; 1:50; loading ...; fig s4d
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in immunocytochemistry on human samples at 1:50 (fig s4d). Nature (2018) ncbi
mouse monoclonal (POH1)
  • immunocytochemistry; human; 1:200; loading ...; fig s4c
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 9116) was used in immunocytochemistry on human samples at 1:200 (fig s4c). Nature (2018) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; mouse; fig 5b
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on mouse samples (fig 5b). Cell Signal (2018) ncbi
domestic rabbit monoclonal (10A11)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2e
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111S) was used in western blot on human samples (fig 2e). Mol Cell (2018) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116P) was used in western blot on human samples (fig 1c). Mol Cell (2017) ncbi
mouse monoclonal (POH1)
  • western blot; human; fig 3b
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig 3b). Gynecol Oncol (2017) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; fig 3b
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples (fig 3b). Gynecol Oncol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on human samples (fig 5a). Sci Rep (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 1g
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig 1g). Sci Rep (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; 1:2000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples at 1:2000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3a
In order to use polo-like kinase 1 inhibitors for a rationally designed chemotherapy protocols to treat patients with metastasized retinoblastoma, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on human samples at 1:1000 (fig 3a). Clin Exp Ophthalmol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig s3
Cell Signaling Technology Cdc2 antibody (Cell Signalling, 9111) was used in western blot on mouse samples (fig s3). PLoS Genet (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig s5
In order to show that fibroblast growth factor 12 regulates the vascular smooth muscle cell switch between synthetic and contractile states, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig s5). Arterioscler Thromb Vasc Biol (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 5c
In order to identify signaling pathways that mediate the EGF-induced epithelial to mesenchymal transition, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig 5c). J Proteomics (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 3
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on mouse samples at 1:500 (fig 3). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Cdc2 antibody (Cell signaling, 9111) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; fig 5
Cell Signaling Technology Cdc2 antibody (Cell signaling, 9116) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 9
Cell Signaling Technology Cdc2 antibody (Cell signaling, 9111s) was used in western blot on human samples (fig 9). EMBO Mol Med (2016) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Cdc2 antibody (Cell Signaling Tech, 9116) was used in western blot on human samples at 1:1000 (fig 4). Mol Med Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111) was used in western blot on human samples (fig 5). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
In order to study quinacrine-induced apoptosis, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9111S) was used in western blot on human samples (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 1b
In order to study quinacrine-induced apoptosis, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; 1:1000; fig 2
In order to investigate factors that control PHD1 activity, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 9116) was used in western blot on human samples at 1:1000 (fig 2). J Cell Sci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 9111) was used in western blot on human samples . Oncogene (2016) ncbi
mouse monoclonal (POH1)
  • western blot; human; fig 2
In order to compare the chemosensitizing effect of nucleoside analogues in cells derived from pancreatic cancer and in osteosarcoma-derived cells, Cell Signaling Technology Cdc2 antibody (Cell signaling, 9116) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (POH1)
  • western blot; human; fig 7
Cell Signaling Technology Cdc2 antibody (Cell signaling, 9116) was used in western blot on human samples (fig 7). Nat Neurosci (2015) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in western blot on human samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in western blot on human samples . DNA Repair (Amst) (2015) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human; fig 2d
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539S) was used in western blot on human samples (fig 2d). J Biol Chem (2014) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; mouse; fig 4
In order to elucidate how parvovirus minute virus of mice halts the cell cycle, Cell Signaling Technology Cdc2 antibody (Cell Signaling, 4539S) was used in western blot on mouse samples (fig 4). PLoS Pathog (2014) ncbi
mouse monoclonal (POH1)
  • western blot; human; loading ...; fig 4e
Cell Signaling Technology Cdc2 antibody (Cell signaling, 9116) was used in western blot on human samples (fig 4e). Int J Oncol (2014) ncbi
domestic rabbit monoclonal (10A11)
  • western blot; human
Cell Signaling Technology Cdc2 antibody (Cell Signaling Technology, 4539) was used in western blot on human samples . Mol Cancer Res (2012) ncbi
BD Biosciences
mouse monoclonal (1/Cdk1/Cdc2)
  • immunohistochemistry; mouse; loading ...
BD Biosciences Cdc2 antibody (BD Biosciences, 610038) was used in immunohistochemistry on mouse samples . Cell Death Differ (2020) ncbi
mouse monoclonal (44/Cdk1/Cdc2)
  • western blot; human; fig 3a
BD Biosciences Cdc2 antibody (BD Bioscience, 612306) was used in western blot on human samples (fig 3a). PLoS Pathog (2017) ncbi
mouse monoclonal (44/Cdk1/Cdc2)
  • western blot; human; loading ...; fig 4a
BD Biosciences Cdc2 antibody (BD Bioscience, 612306) was used in western blot on human samples (fig 4a). Int J Mol Sci (2016) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • immunoprecipitation; mouse; 1:1000; loading ...; fig s12h
  • western blot; mouse; 1:1000; loading ...; fig s12h
BD Biosciences Cdc2 antibody (BD Biosciences, 610038) was used in immunoprecipitation on mouse samples at 1:1000 (fig s12h) and in western blot on mouse samples at 1:1000 (fig s12h). Science (2016) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • western blot; human; fig 2c
BD Biosciences Cdc2 antibody (BD Pharmingen, 610037) was used in western blot on human samples (fig 2c). Onco Targets Ther (2015) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • immunoprecipitation; human; fig 4
  • western blot; human; 1:500; fig 4
BD Biosciences Cdc2 antibody (BD, 610037) was used in immunoprecipitation on human samples (fig 4) and in western blot on human samples at 1:500 (fig 4). Cell Rep (2015) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • western blot; human; fig s2
BD Biosciences Cdc2 antibody (BD Transduction, 610038) was used in western blot on human samples (fig s2). Sci Rep (2015) ncbi
mouse monoclonal (44/Cdk1/Cdc2)
  • western blot; human; 1:250; fig 5
BD Biosciences Cdc2 antibody (BD Biosciences, 612306) was used in western blot on human samples at 1:250 (fig 5). Front Microbiol (2015) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • western blot; human
In order to study the effect of MASTL on cyclin B1 degradation and its mechanism, BD Biosciences Cdc2 antibody (BD Transduction, 610038) was used in western blot on human samples . Biol Open (2015) ncbi
mouse monoclonal (1/Cdk1/Cdc2)
  • immunocytochemistry; human
In order to identify the role of PCTAIRE1 in cancer cells, BD Biosciences Cdc2 antibody (BD, 610037) was used in immunocytochemistry on human samples . Cancer Res (2014) ncbi
Articles Reviewed
  1. Wang P, Huang Z, Peng Y, Li H, Lin T, Zhao Y, et al. Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair. Nat Commun. 2022;13:6502 pubmed publisher
  2. Fei X, Wu X, Dou Y, Sun K, Guo Q, Zhang L, et al. TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I. Mol Ther Oncolytics. 2022;26:413-428 pubmed publisher
  3. Hicks T, Koury E, McCabe C, Williams C, Crahan C, Smolikove S. R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germline. Nucleic Acids Res. 2022;50:8041-8059 pubmed publisher
  4. Mandic R, Marquardt A, Terhorst P, Ali U, Nowak Rossmann A, Cai C, et al. The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC. BMC Cancer. 2022;22:785 pubmed publisher
  5. Taniguchi H, Caeser R, Chavan S, Zhan Y, Chow A, Manoj P, et al. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep. 2022;39:110814 pubmed publisher
  6. Deng Y, Li Y, Wu T, Chen X, Li X, Cai K, et al. RAD6 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma by Regulating Histone Ubiquitination of CCNB1. Biol Proced Online. 2022;24:4 pubmed publisher
  7. Liu X, Liu Y, Liu Z, Lin C, Meng F, Xu L, et al. CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner. Mol Cancer. 2021;20:114 pubmed publisher
  8. Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
  9. Laliotis G, Chavdoula E, Paraskevopoulou M, Kaba A, La Ferlita A, Singh S, et al. AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing. Nat Commun. 2021;12:4624 pubmed publisher
  10. Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher
  11. Wu Y, Liu Y, Hu Y, Wang L, Bai F, Xu C, et al. Control of multiciliogenesis by miR-34/449 in the male reproductive tract through enforcing cell cycle exit. J Cell Sci. 2021;134: pubmed publisher
  12. Grandits A, Nguyen C, Schlerka A, Hackl H, Sill H, Etzler J, et al. Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness. Leukemia. 2021;35:2827-2839 pubmed publisher
  13. Zhou Z, Tan F, Pei Q, Li C, Zhou Y, Li Y, et al. lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis. Aging (Albany NY). 2021;13:9838-9858 pubmed publisher
  14. Ye S, Sharipova D, Kozinova M, Klug L, D Souza J, Belinsky M, et al. Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment. JCI Insight. 2021;6: pubmed publisher
  15. Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
  16. Brunner A, Suryo Rahmanto A, Johansson H, Franco M, Viiliäinen J, Gazi M, et al. PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. elife. 2020;9: pubmed publisher
  17. Liu H, Guo D, Sha Y, Zhang C, Jiang Y, Hong L, et al. ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L. Aging (Albany NY). 2020;12:11100-11115 pubmed publisher
  18. Shinada M, Kato D, Kamoto S, Yoshimoto S, Tsuboi M, Yoshitake R, et al. PDPN Is Expressed in Various Types of Canine Tumors and Its Silencing Induces Apoptosis and Cell Cycle Arrest in Canine Malignant Melanoma. Cells. 2020;9: pubmed publisher
  19. Liu J, Liu Z, Wu Q, Lu Y, Wong C, Miao L, et al. Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming. Nat Commun. 2020;11:1507 pubmed publisher
  20. Sousounis K, Bryant D, Martínez Fernández J, Eddy S, Tsai S, Gundberg G, et al. Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration. elife. 2020;9: pubmed publisher
  21. Shah D, Nisr R, Stretton C, Krasteva Christ G, Hundal H. Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function. J Cachexia Sarcopenia Muscle. 2020;11:838-858 pubmed publisher
  22. Aldonza M, Ku J, Hong J, Kim D, Yu S, Lee M, et al. Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020;6:eaav7416 pubmed publisher
  23. Sanz Gómez N, de Pedro I, Ortigosa B, Santamaria D, Malumbres M, de Carcer G, et al. Squamous differentiation requires G2/mitosis slippage to avoid apoptosis. Cell Death Differ. 2020;27:2451-2467 pubmed publisher
  24. de Jong M, Langendonk M, Reitsma B, Herbers P, Lodewijk M, Nijland M, et al. WEE1 inhibition synergizes with CHOP chemotherapy and radiation therapy through induction of premature mitotic entry and DNA damage in diffuse large B-cell lymphoma. Ther Adv Hematol. 2020;11:2040620719898373 pubmed publisher
  25. Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed publisher
  26. Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, et al. SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG. Cell Death Dis. 2019;10:794 pubmed publisher
  27. Li R, Guo M, Song L. PAS Domain Containing Repressor 1 (PASD1) Promotes Glioma Cell Proliferation Through Inhibiting Apoptosis In Vitro. Med Sci Monit. 2019;25:6955-6964 pubmed publisher
  28. Frottin F, Schueder F, Tiwary S, Gupta R, Korner R, Schlichthaerle T, et al. The nucleolus functions as a phase-separated protein quality control compartment. Science. 2019;365:342-347 pubmed publisher
  29. Liu X, Zhao P, Wang X, Wang L, Zhu Y, Song Y, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184 pubmed publisher
  30. Choi Y, Kang M, Hong K, Kim J. Tubastatin A inhibits HDAC and Sirtuin activity rather than being a HDAC6-specific inhibitor in mouse oocytes. Aging (Albany NY). 2019;11:1759-1777 pubmed publisher
  31. Walton C, Zhang W, Patiño Parrado I, Barrio Alonso E, Garrido J, Frade J. Primary neurons can enter M-phase. Sci Rep. 2019;9:4594 pubmed publisher
  32. Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed publisher
  33. Lee J, Sung J, Choi E, Yoon H, Kang B, Hong E, et al. C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle. Cells. 2019;8: pubmed publisher
  34. Qi D, Hu L, Jiao T, Zhang T, Tong X, Ye X. Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity. J Virol. 2018;92: pubmed publisher
  35. Rai A, Chen J, Selbach M, Pelkmans L. Kinase-controlled phase transition of membraneless organelles in mitosis. Nature. 2018;559:211-216 pubmed publisher
  36. Lee C, Hsieh T. Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018;47:16-26 pubmed publisher
  37. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  38. Huang T, Fowler F, Chen C, Shen Z, SLECKMAN B, Tyler J. The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. Mol Cell. 2018;69:879-892.e5 pubmed publisher
  39. Geng Y, Michowski W, Chick J, Wang Y, Jecrois M, Sweeney K, et al. Kinase-independent function of E-type cyclins in liver cancer. Proc Natl Acad Sci U S A. 2018;115:1015-1020 pubmed publisher
  40. Wang Y, Liu X, Zhou L, Duong D, Bhuripanyo K, Zhao B, et al. Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer. Nat Commun. 2017;8:2232 pubmed publisher
  41. Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed publisher
  42. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  43. Huang C, Wu S, Ji H, Yan X, Xie Y, Murai S, et al. Identification of XBP1-u as a novel regulator of the MDM2/p53 axis using an shRNA library. Sci Adv. 2017;3:e1701383 pubmed publisher
  44. Zhu Z, Lou C, Zheng Z, Zhu R, Tian S, Xie C, et al. ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer. Gynecol Oncol. 2017;147:418-425 pubmed publisher
  45. Giono L, Resnick Silverman L, Carvajal L, St Clair S, Manfredi J. Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase. Oncogene. 2017;36:6762-6773 pubmed publisher
  46. Zhang T, Du W, Wilson A, Namekawa S, Andreassen P, Meetei A, et al. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep. 2017;7:45626 pubmed publisher
  47. Xu P, Zhou Z, Xiong M, Zou W, Deng X, Ganaie S, et al. Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway. PLoS Pathog. 2017;13:e1006266 pubmed publisher
  48. Folco H, Chalamcharla V, Sugiyama T, Thillainadesan G, Zofall M, Balachandran V, et al. Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy. Nature. 2017;543:126-130 pubmed publisher
  49. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  50. Graziano A, Cardile V, Avola R, Vicario N, Parenti C, Salvatorelli L, et al. Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation. Oncotarget. 2017;8:13917-13931 pubmed publisher
  51. Peng Y, Shi X, Li Z, He X, Sun Y. Particularly interesting Cys-His-rich protein is highly expressed in human intracranial aneurysms and resists aneurysmal rupture. Exp Ther Med. 2016;12:3905-3912 pubmed publisher
  52. Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed publisher
  53. Ramos P, Guerra A, Guerreiro O, Santos S, Oliveira H, Freire C, et al. Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts. Int J Mol Sci. 2016;18: pubmed publisher
  54. Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
  55. Huang Z, Zhou X, He Y, Ke X, Wen Y, Zou F, et al. Hyperthermia enhances 17-DMAG efficacy in hepatocellular carcinoma cells with aggravated DNA damage and impaired G2/M transition. Sci Rep. 2016;6:38072 pubmed publisher
  56. Li H, Wang R, Jiang H, Zhang E, Tan J, Xu H, et al. Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function. DNA Cell Biol. 2016;35:680-690 pubmed
  57. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  58. Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  59. Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
  60. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  61. Schwermer M, Dreesmann S, Eggert A, Althoff K, Steenpass L, Schramm A, et al. Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines. Clin Exp Ophthalmol. 2017;45:288-296 pubmed publisher
  62. Diril M, Bisteau X, Kitagawa M, Caldez M, Wee S, Gunaratne J, et al. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genet. 2016;12:e1006310 pubmed publisher
  63. Song S, Kim K, Jo E, Kim Y, Kwon J, Bae S, et al. Fibroblast Growth Factor 12 Is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate. Arterioscler Thromb Vasc Biol. 2016;36:1928-36 pubmed publisher
  64. Grassi M, Palma C, Thomé C, Lanfredi G, Poersch A, Faça V. Proteomic analysis of ovarian cancer cells during epithelial-mesenchymal transition (EMT) induced by epidermal growth factor (EGF) reveals mechanisms of cell cycle control. J Proteomics. 2017;151:2-11 pubmed publisher
  65. Helland Ø, Popa M, Bischof K, Gjertsen B, McCormack E, Bjørge L. The HDACi Panobinostat Shows Growth Inhibition Both In Vitro and in a Bioluminescent Orthotopic Surgical Xenograft Model of Ovarian Cancer. PLoS ONE. 2016;11:e0158208 pubmed publisher
  66. Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
  67. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  68. Al Nakouzi N, Wang C, Beraldi E, Jäger W, Ettinger S, Fazli L, et al. Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis. EMBO Mol Med. 2016;8:761-78 pubmed publisher
  69. Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, et al. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nat Commun. 2016;7:11363 pubmed publisher
  70. Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed publisher
  71. Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed publisher
  72. Heilmann T, Dittmann L, van Mackelenbergh M, Mundhenke C, Weimer J, Arnold N, et al. Head-to-head comparison of the impact of Aurora A, Aurora B, Repp86, CDK1, CDK2 and Ki67 expression in two of the most relevant gynaecological tumor entities. Arch Gynecol Obstet. 2016;294:813-23 pubmed publisher
  73. Cheng C, Jiao J, Qian Y, Guo X, Huang J, Dai M, et al. Curcumin induces G2/M arrest and triggers apoptosis via FoxO1 signaling in U87 human glioma cells. Mol Med Rep. 2016;13:3763-70 pubmed publisher
  74. Chang L, Huang J, Wang K, Li J, Yan R, Zhu L, et al. Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy. BMC Cancer. 2016;16:190 pubmed publisher
  75. Zhang W, Liang Z, Li J. Inhibition of rhotekin exhibits antitumor effects in lung cancer cells. Oncol Rep. 2016;35:2529-34 pubmed publisher
  76. Zhang M, Linghu E, Zhan Q, He T, Cao B, Brock M, et al. Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling. Oncotarget. 2016;7:17957-69 pubmed publisher
  77. Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  78. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  79. Choe C, Shin Y, Kim C, Choi S, Lee J, Kim S, et al. Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition. Onco Targets Ther. 2015;8:3665-78 pubmed publisher
  80. Toledo C, Ding Y, Hoellerbauer P, Davis R, Basom R, Girard E, et al. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Rep. 2015;13:2425-2439 pubmed publisher
  81. Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  82. Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher
  83. dos Santos N, Matias A, Higa G, Kihara A, Cerchiaro G. Copper Uptake in Mammary Epithelial Cells Activates Cyclins and Triggers Antioxidant Response. Oxid Med Cell Longev. 2015;2015:162876 pubmed publisher
  84. Lohberger B, Leithner A, Stuendl N, Kaltenegger H, Kullich W, Steinecker Frohnwieser B. Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation. BMC Cancer. 2015;15:891 pubmed publisher
  85. Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed publisher
  86. Voets E, Marsman J, Demmers J, Beijersbergen R, Wolthuis R. The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1. Sci Rep. 2015;5:14798 pubmed publisher
  87. Li X, Liang Q, Liu W, Zhang N, Xu L, Zhang X, et al. Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. Oncogene. 2016;35:2453-64 pubmed publisher
  88. Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher
  89. Caspari T, Hilditch V. Two Distinct Cdc2 Pools Regulate Cell Cycle Progression and the DNA Damage Response in the Fission Yeast S.pombe. PLoS ONE. 2015;10:e0130748 pubmed publisher
  90. Arana M, Tocchetti G, Domizi P, Arias A, Rigalli J, Ruiz M, et al. Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance. Toxicol Appl Pharmacol. 2015;287:178-90 pubmed publisher
  91. Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed
  92. Li C, Wu W, Wu W, Liao Y, Chen L, Huang C, et al. The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma. Oncotarget. 2015;6:9220-39 pubmed
  93. Suzuki M, Takeda T, Nakagawa H, Iwata S, Watanabe T, Siddiquey M, et al. The heat shock protein 90 inhibitor BIIB021 suppresses the growth of T and natural killer cell lymphomas. Front Microbiol. 2015;6:280 pubmed publisher
  94. Garg A, Futcher B, Leatherwood J. A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression. Nucleic Acids Res. 2015;43:6874-88 pubmed publisher
  95. Voets E, Wolthuis R. MASTL promotes cyclin B1 destruction by enforcing Cdc20-independent binding of cyclin B1 to the APC/C. Biol Open. 2015;4:484-95 pubmed publisher
  96. Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher
  97. Hsieh W, Huang Y, Wang T, Ming Y, Tsai C, Pang J. IFI27, a novel epidermal growth factor-stabilized protein, is functionally involved in proliferation and cell cycling of human epidermal keratinocytes. Cell Prolif. 2015;48:187-97 pubmed publisher
  98. Yuan S, Vilimas P, Zagorodnyuk V, Gibbins I. Novel spinal pathways identified by neuronal c-Fos expression after urethrogenital reflex activation in female guinea pigs. Neuroscience. 2015;288:37-50 pubmed publisher
  99. Hasegawa H, Ishibashi K, Kubota S, Yamaguchi C, Yuki R, Nakajo H, et al. Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase. PLoS ONE. 2014;9:e116048 pubmed publisher
  100. Sung W, Lin Y, Wu P, Yen H, Lai H, Su T, et al. High nuclear/cytoplasmic ratio of Cdk1 expression predicts poor prognosis in colorectal cancer patients. BMC Cancer. 2014;14:951 pubmed publisher
  101. Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  102. Jirawatnotai S, Sharma S, Michowski W, Suktitipat B, Geng Y, Quackenbush J, et al. The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis. Cell Cycle. 2014;13:2889-900 pubmed publisher
  103. Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-1139 pubmed publisher
  104. Munday D, Wu W, Smith N, Fix J, Noton S, Galloux M, et al. Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis. J Virol. 2015;89:917-30 pubmed publisher
  105. Li N, Fassl A, Chick J, Inuzuka H, Li X, Mansour M, et al. Cyclin C is a haploinsufficient tumour suppressor. Nat Cell Biol. 2014;16:1080-91 pubmed publisher
  106. Pattabiraman C, Hong S, Gunasekharan V, Pranatharthi A, Bajaj J, Srivastava S, et al. CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits. Cancer Res. 2014;74:6682-92 pubmed publisher
  107. Yanagi T, Krajewska M, Matsuzawa S, Reed J. PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. Cancer Res. 2014;74:5795-807 pubmed publisher
  108. Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed publisher
  109. Silva A, Santos A, Farfel J, Grinberg L, Ferretti R, Campos A, et al. Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease. PLoS ONE. 2014;9:e99897 pubmed publisher
  110. Hou Z, Zhao W, Zhou J, Shen L, Zhan P, Xu C, et al. A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival. Int J Biochem Cell Biol. 2014;53:380-8 pubmed publisher
  111. Rodríguez Gabriel M. Analyzing Cdc2/Cdk1 activation during stress response in Schizosaccharomyces pombe. Methods Mol Biol. 2014;1170:383-92 pubmed publisher
  112. Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed publisher
  113. Scharfmann R, Pechberty S, Hazhouz Y, von Bülow M, Bricout Neveu E, Grenier Godard M, et al. Development of a conditionally immortalized human pancreatic ? cell line. J Clin Invest. 2014;124:2087-98 pubmed publisher
  114. Fukumoto Y, Morii M, Miura T, Kubota S, Ishibashi K, Honda T, et al. Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint. J Biol Chem. 2014;289:12313-29 pubmed publisher
  115. Kaur S, Fielding A, Gassner G, Carter N, Royle S. An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis. elife. 2014;3:e00829 pubmed publisher
  116. Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
  117. Adeyemi R, Pintel D. Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells. PLoS Pathog. 2014;10:e1003891 pubmed publisher
  118. Xia Q, Cai Y, Peng R, Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014;44:735-44 pubmed publisher
  119. Bana E, Sibille E, Valente S, Cerella C, Chaimbault P, Kirsch G, et al. A novel coumarin-quinone derivative SV37 inhibits CDC25 phosphatases, impairs proliferation, and induces cell death. Mol Carcinog. 2015;54:229-41 pubmed publisher
  120. Tan E, Caro S, Potnis A, Lanza C, Slawson C. O-linked N-acetylglucosamine cycling regulates mitotic spindle organization. J Biol Chem. 2013;288:27085-99 pubmed publisher
  121. Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed publisher
  122. Diril M, Ratnacaram C, Padmakumar V, Du T, Wasser M, Coppola V, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci U S A. 2012;109:3826-31 pubmed publisher
  123. Garimella S, Rocca A, Lipkowitz S. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Mol Cancer Res. 2012;10:75-85 pubmed publisher
  124. Hsu F, Yang M, Lin E, Tseng C, Lin H. The significance of Her2 on androgen receptor protein stability in the transition of androgen requirement in prostate cancer cells. Am J Physiol Endocrinol Metab. 2011;300:E902-8 pubmed publisher
  125. Inaki M, Kato D, Utsugi T, Onoda F, Hanaoka F, Murakami Y. Genetic analyses using a mouse cell cycle mutant identifies magoh as a novel gene involved in Cdk regulation. Genes Cells. 2011;16:166-78 pubmed publisher
  126. Kim A, Joseph S, Khan A, Epstein C, Sobel R, Huang T. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radic Biol Med. 2010;48:1501-12 pubmed publisher