This is a Validated Antibody Database (VAD) review about human CYP1A2, based on 8 published articles (read how Labome selects the articles), using CYP1A2 antibody in all methods. It is aimed to help Labome visitors find the most suited CYP1A2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CYP1A2 synonym: CP12; CYPIA2; P3-450; P450(PA)

Santa Cruz Biotechnology
mouse monoclonal (d15)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 8g
  • immunocytochemistry; human; 1:200; loading ...; fig 6s1d
Santa Cruz Biotechnology CYP1A2 antibody (Santa Cruz, sc-53241) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 8g) and in immunocytochemistry on human samples at 1:200 (fig 6s1d). elife (2019) ncbi
mouse monoclonal
  • western blot; human; 1:500; loading ...; fig 6h
Santa Cruz Biotechnology CYP1A2 antibody (SantaCruz, sc-393783) was used in western blot on human samples at 1:500 (fig 6h). Biochem Pharmacol (2017) ncbi
mouse monoclonal (d15)
  • western blot; mouse; 1:1000; loading ...; fig 10a
Santa Cruz Biotechnology CYP1A2 antibody (SantaCruz, sc-53241) was used in western blot on mouse samples at 1:1000 (fig 10a). Drug Metab Dispos (2017) ncbi
mouse monoclonal (3B8C1)
  • western blot; human; loading ...; fig 6b
Santa Cruz Biotechnology CYP1A2 antibody (Santa Cruz, sc-53614) was used in western blot on human samples (fig 6b). Toxicol Lett (2016) ncbi
mouse monoclonal (d15)
  • western blot; human; fig 2
Santa Cruz Biotechnology CYP1A2 antibody (Santa Cruz, SC-53241) was used in western blot on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (3B8C1)
  • western blot; human
In order to study the co-culture of mesenchymal stem cells with liver cells in bioartificial liver system, Santa Cruz Biotechnology CYP1A2 antibody (Santa Cruz Biotechnology, sc-53614) was used in western blot on human samples . Biotechnol Bioeng (2013) ncbi
Enzo Life Sciences
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 8i
Enzo Life Sciences CYP1A2 antibody (Enzo, BML-CR3130-0100) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 8i). elife (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1d
In order to test the toxicity of The gamma-hydroxybutyric acid receptor antagonist NCS-382 in HepG2 and primary hepatocyte cells, Invitrogen CYP1A2 antibody (ThermoFisher, PA1-341) was used in western blot on human samples (fig 1d). Toxicol In Vitro (2017) ncbi
EMD Millipore
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 4b
EMD Millipore CYP1A2 antibody (Millipore, AB1248) was used in western blot on human samples at 1:2000 (fig 4b). Front Physiol (2016) ncbi
Articles Reviewed
  1. Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
  2. Chen Y, Zeng L, Wang Y, Tolleson W, Knox B, Chen S, et al. The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p. Biochem Pharmacol. 2017;145:178-191 pubmed publisher
  3. Cheng S, Bammler T, Cui J. RNA Sequencing Reveals Age and Species Differences of Constitutive Androstane Receptor-Targeted Drug-Processing Genes in the Liver. Drug Metab Dispos. 2017;45:867-882 pubmed publisher
  4. Vogel K, Ainslie G, Roullet J, McConnell A, Gibson K. In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of ?-hydroxybutyrate (GHB) binding. Toxicol In Vitro. 2017;40:196-202 pubmed publisher
  5. Prieto P, Fernandez Velasco M, Fernández Santos M, Sanchez P, Terrón V, Martín Sanz P, et al. Cell Expansion-Dependent Inflammatory and Metabolic Profile of Human Bone Marrow Mesenchymal Stem Cells. Front Physiol. 2016;7:548 pubmed
  6. Štěpánková M, Krasulová K, Doricakova A, Kurka O, Anzenbacher P, Dvorak Z. Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450. Toxicol Lett. 2016;262:173-186 pubmed publisher
  7. Rasmussen M, Balaguer P, Ekstrand B, Daujat Chavanieu M, Gerbal Chaloin S. Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes. PLoS ONE. 2016;11:e0154629 pubmed publisher
  8. Yang Y, Li J, Pan X, Zhou P, Yu X, Cao H, et al. Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system. Biotechnol Bioeng. 2013;110:958-68 pubmed publisher