This is a Validated Antibody Database (VAD) review about human CXCR2, based on 15 published articles (read how Labome selects the articles), using CXCR2 antibody in all methods. It is aimed to help Labome visitors find the most suited CXCR2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CXCR2 synonym: CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB

Abcam
domestic rabbit monoclonal (EPR22301-103)
  • immunohistochemistry - paraffin section; human; loading ...; fig s5e
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s5e
Abcam CXCR2 antibody (Abcam, ab225732) was used in immunohistochemistry - paraffin section on human samples (fig s5e) and in immunohistochemistry - paraffin section on mouse samples (fig s5e). Cell Death Dis (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1d
Abcam CXCR2 antibody (Abcam, ab217314) was used in immunohistochemistry on mouse samples (fig 1d). Front Physiol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig s2a
  • western blot; human; 1:500; loading ...; fig 4g
Abcam CXCR2 antibody (Abcam, ab65968) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s2a) and in western blot on human samples at 1:500 (fig 4g). PLoS ONE (2020) ncbi
BioLegend
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; loading ...; fig 2a
BioLegend CXCR2 antibody (BioLegend, 5E8) was used in flow cytometry on human samples (fig 2a). Clin Exp Immunol (2019) ncbi
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; loading ...; fig 2b
BioLegend CXCR2 antibody (BioLegend, 5E8) was used in flow cytometry on human samples (fig 2b). Front Immunol (2019) ncbi
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; loading ...; fig s2b
BioLegend CXCR2 antibody (Biolegend, 320705) was used in flow cytometry on human samples (fig s2b). Cell (2019) ncbi
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; loading ...; fig 2
BioLegend CXCR2 antibody (BioLegend, 320,706) was used in flow cytometry on human samples (fig 2). Immun Ageing (2017) ncbi
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; fig 7b
BioLegend CXCR2 antibody (BioLegend, 5E8/CXCR2) was used in flow cytometry on human samples (fig 7b). J Infect (2017) ncbi
mouse monoclonal (5E8/CXCR2)
  • flow cytometry; human; fig 1
In order to examine the contribution of stromal cells to non-small cell lung cancer, BioLegend CXCR2 antibody (BioLegend, 5E8) was used in flow cytometry on human samples (fig 1). PLoS ONE (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-2)
  • immunocytochemistry; human; fig 6d
Santa Cruz Biotechnology CXCR2 antibody (Santa Cruz, SC-7304) was used in immunocytochemistry on human samples (fig 6d). Toxins (Basel) (2017) ncbi
mouse monoclonal (E-2)
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology CXCR2 antibody (Santa Cruz, sc-7304) was used in western blot on human samples (fig 4c). J Biol Chem (2017) ncbi
mouse monoclonal (E-2)
  • western blot; human; fig 1
Santa Cruz Biotechnology CXCR2 antibody (Santa Cruz, sc-7304) was used in western blot on human samples (fig 1). Sci Rep (2015) ncbi
Invitrogen
mouse monoclonal (eBio5E8-C7-F10 (5E8-C7-F10))
  • flow cytometry; human; loading ...; tbl 2
In order to correlate neutrophil functions with habitual physical activity, Invitrogen CXCR2 antibody (eBiosciences, 5E8-C7-F10) was used in flow cytometry on human samples (tbl 2). Brain Behav Immun (2016) ncbi
mouse monoclonal (eBio5E8-C7-F10 (5E8-C7-F10))
  • flow cytometry; human; loading ...; fig 6c
In order to study the effects of IFN signaling on neutrophil polarization, Invitrogen CXCR2 antibody (eBioscience, 5E8-C7-F10) was used in flow cytometry on human samples (fig 6c). Int J Cancer (2016) ncbi
Alpha Diagnostics
domestic rabbit
  • western blot; human; 1:250; fig 3c
Alpha Diagnostics CXCR2 antibody (Alpha Diagnostics, GALR21-A) was used in western blot on human samples at 1:250 (fig 3c). Nat Commun (2015) ncbi
Articles Reviewed
  1. Wu T, Wang W, Shi G, Hao M, Wang Y, Yao M, et al. Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression. Cell Death Dis. 2022;13:624 pubmed publisher
  2. Xu M, Zheng X, Wang D, Fu X, Xing Y, Liu Y, et al. Blockage of C-X-C Motif Chemokine Receptor 2 (CXCR2) Suppressed Uric Acid (UA)-Induced Cardiac Remodeling. Front Physiol. 2021;12:700338 pubmed publisher
  3. Ando Y, Ohuchida K, Otsubo Y, Kibe S, Takesue S, Abe T, et al. Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5. PLoS ONE. 2020;15:e0228015 pubmed publisher
  4. Lau E, Carroll E, Callender L, Hood G, Berryman V, Pattrick M, et al. Type 2 diabetes is associated with the accumulation of senescent T cells. Clin Exp Immunol. 2019;197:205-213 pubmed publisher
  5. Lim S, Kim J, Jeon S, Shin M, Kwon J, Kim T, et al. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Front Immunol. 2019;10:496 pubmed publisher
  6. Collins P, Cella M, Porter S, Li S, Gurewitz G, Hong H, et al. Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells. Cell. 2019;176:348-360.e12 pubmed publisher
  7. Krogh Nielsen M, Hector S, Allen K, Subhi Y, Sørensen T. Altered activation state of circulating neutrophils in patients with neovascular age-related macular degeneration. Immun Ageing. 2017;14:18 pubmed publisher
  8. Gillman A, Breshears L, Kistler C, Finnegan P, Torres V, Schlievert P, et al. Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel). 2017;9: pubmed publisher
  9. Janesch P, Rouha H, Weber S, Malafa S, Gross K, Maierhofer B, et al. Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8. J Infect. 2017;74:473-483 pubmed publisher
  10. Gatla H, Zou Y, Uddin M, Singha B, Bu P, Vancura A, et al. Histone Deacetylase (HDAC) Inhibition Induces IκB Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells. J Biol Chem. 2017;292:5043-5054 pubmed publisher
  11. Bartlett D, Fox O, McNulty C, Greenwood H, Murphy L, Sapey E, et al. Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults. Brain Behav Immun. 2016;56:12-20 pubmed publisher
  12. Andzinski L, Kasnitz N, Stahnke S, Wu C, Gereke M, von Köckritz Blickwede M, et al. Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human. Int J Cancer. 2016;138:1982-93 pubmed publisher
  13. Renga B, Francisci D, Carino A, Marchianò S, Cipriani S, Chiara Monti M, et al. The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma. Sci Rep. 2015;5:15403 pubmed publisher
  14. Durrans A, Gao D, Gupta R, Fischer K, Choi H, El Rayes T, et al. Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC. PLoS ONE. 2015;10:e0129123 pubmed publisher
  15. SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed publisher