This is a Validated Antibody Database (VAD) review about human CX3CR1, based on 38 published articles (read how Labome selects the articles), using CX3CR1 antibody in all methods. It is aimed to help Labome visitors find the most suited CX3CR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CX3CR1 synonym: CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28

BioLegend
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples . J Exp Med (2022) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; mouse; loading ...; fig 5a
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on mouse samples (fig 5a). elife (2021) ncbi
rat monoclonal (2A9-1)
  • mass cytometry; human; 1:50; loading ...; fig s2
BioLegend CX3CR1 antibody (Biolegend, 2A91) was used in mass cytometry on human samples at 1:50 (fig s2). Int J Mol Sci (2021) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; 1:20; loading ...; fig 3c, 3e
BioLegend CX3CR1 antibody (Biolegend, 341604) was used in flow cytometry on human samples at 1:20 (fig 3c, 3e). Nat Neurosci (2021) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; 1:100; loading ...
BioLegend CX3CR1 antibody (Biolegend, 341617) was used in flow cytometry on human samples at 1:100. bioRxiv (2020) ncbi
mouse monoclonal (K0124E1)
  • mass cytometry; human; loading ...; fig 1b, 1d, s2
BioLegend CX3CR1 antibody (Biolegend, K0124E1) was used in mass cytometry on human samples (fig 1b, 1d, s2). Cell Rep (2019) ncbi
mouse monoclonal (8E10.D9)
  • immunohistochemistry - frozen section; gerbils; 1:100; loading ...; fig 5a
  • western blot; gerbils; 1:1000; loading ...; fig 1
BioLegend CX3CR1 antibody (BioLegend, 824001) was used in immunohistochemistry - frozen section on gerbils samples at 1:100 (fig 5a) and in western blot on gerbils samples at 1:1000 (fig 1). Int J Mol Med (2019) ncbi
mouse monoclonal (K0124E1)
  • flow cytometry; human; loading ...; fig 2e
BioLegend CX3CR1 antibody (BioLegend, K0124E1) was used in flow cytometry on human samples (fig 2e). Clin Exp Immunol (2019) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; 1:100; loading ...; fig 1h
BioLegend CX3CR1 antibody (Biolegend, 341606) was used in flow cytometry on human samples at 1:100 (fig 1h). Cancer Cell (2019) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig s2b
BioLegend CX3CR1 antibody (Biolegend, 341604) was used in flow cytometry on human samples (fig s2b). Cell (2019) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig 1e
BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used in flow cytometry on human samples (fig 1e). J Exp Med (2018) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig 2d
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples (fig 2d). Ann Rheum Dis (2018) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig s1
In order to evaluate the effectiveness of adoptive natural killer cell therapy against the pulmonary metastasis of Ewing sarcoma, BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used in flow cytometry on human samples (fig s1). Oncoimmunology (2017) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig 2a
In order to map the lineage of human dendritic cells, BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used in flow cytometry on human samples (fig 2a). Science (2017) ncbi
mouse monoclonal (K0124E1)
  • mass cytometry; human; loading ...; fig 1j
In order to map the lineage of human dendritic cells, BioLegend CX3CR1 antibody (BioLegend, KO124E1) was used in mass cytometry on human samples (fig 1j). Science (2017) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
rat monoclonal (2A9-1)
BioLegend CX3CR1 antibody (Biolegend, 341609) was used . Sci Rep (2017) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human
In order to characterize activated T cells in joint tissue from patients with rheumatoid arthritis, BioLegend CX3CR1 antibody (biolegend, 2A9-1) was used in flow cytometry on human samples . Nature (2017) ncbi
mouse monoclonal (K0124E1)
  • flow cytometry; human; loading ...; tbl 1
In order to demonstrate that freezing already-stained samples suspended in 10% DMSO in FBS is practical and efficient way to preserve already-stained samples for mass cytometry assessment, BioLegend CX3CR1 antibody (Biolegend, K0124E1) was used in flow cytometry on human samples (tbl 1). Cytometry A (2017) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 1e
In order to investigate the role of Eomes in the retention of liver natural killer cells, BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used in flow cytometry on human samples (fig 1e). J Immunol (2016) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 5
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples (fig 5). PLoS Pathog (2016) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 6
BioLegend CX3CR1 antibody (Biolegend, 341610) was used in flow cytometry on human samples (fig 6). PLoS ONE (2015) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 3
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples (fig 3). Clin Cancer Res (2015) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 3
In order to study human cord blood and bone marrow for restricted dendritic cell and monocyte progenitors, BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples (fig 3). J Exp Med (2015) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human
BioLegend CX3CR1 antibody (Biolegend, 2A9-1) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
rat monoclonal (2A9-1)
BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used . Physiol Rep (2014) ncbi
rat monoclonal (2A9-1)
BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used . J Exp Med (2014) ncbi
rat monoclonal (2A9-1)
In order to correlate biomarkers associated with coagulation, monocyte activation, and inflammation in elite controllers of HIV infection, BioLegend CX3CR1 antibody (BioLegend, 2A9-1) was used . J Infect Dis (2014) ncbi
Invitrogen
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig s3
Invitrogen CX3CR1 antibody (eBioscience, 2A9-1) was used in flow cytometry on human samples (fig s3). Eur J Immunol (2019) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; fig 2a
Invitrogen CX3CR1 antibody (eBioscience, 2A9-1) was used in flow cytometry on human samples (fig 2a). Front Immunol (2017) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig 3B
In order to analyze the frequency and phenotype of monocyte subpopulations in peripheral blood, cerebrospinal fluid, and brain biopsy material derived from multiple sclerosis patients, Invitrogen CX3CR1 antibody (eBioscience, 2A9-1) was used in flow cytometry on human samples (fig 3B). J Immunol (2016) ncbi
rat monoclonal (2A9-1)
  • flow cytometry; human
Invitrogen CX3CR1 antibody (eBioscience, 2A9-1) was used in flow cytometry on human samples . J Infect Dis (2014) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 4a
Abcam CX3CR1 antibody (Abcam, ab8021) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 4a). Front Pharmacol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 3a
Abcam CX3CR1 antibody (Abcam, 8021) was used in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig 3a). Front Immunol (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4
Abcam CX3CR1 antibody (Abcam, ab8021) was used in western blot on mouse samples (fig 4). Int J Mol Med (2016) ncbi
Abnova
mouse polyclonal
  • immunocytochemistry; human; 1:500; fig 1c
Abnova CX3CR1 antibody (Novus Biologicals, H00001524-B01P) was used in immunocytochemistry on human samples at 1:500 (fig 1c). Mol Psychiatry (2017) ncbi
MBL International
  • flow cytometry; human; loading ...; fig 1d
MBL International CX3CR1 antibody (MBL, D070-4) was used in flow cytometry on human samples (fig 1d). PLoS ONE (2016) ncbi
  • flow cytometry; human
In order to describe protocols for immunostaining and multiparameter flow cytometric analysis of major human antigen-presenting cells in peripheral blood, MBL International CX3CR1 antibody (MBL International, D070-4) was used in flow cytometry on human samples . Nat Protoc (2010) ncbi
BD Biosciences
rat monoclonal (2A9-1)
  • flow cytometry; human; loading ...; fig 4a
BD Biosciences CX3CR1 antibody (BD Biosciences, 2A9-1) was used in flow cytometry on human samples (fig 4a). J Immunol (2019) ncbi
Articles Reviewed
  1. Amaral E, Foreman T, Namasivayam S, Hilligan K, Kauffman K, Barbosa Bomfim C, et al. GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection. J Exp Med. 2022;219: pubmed publisher
  2. Yu S, Cheng L, Tian D, Li Z, Yao F, Luo Y, et al. Fascin-1 is Highly Expressed Specifically in Microglia After Spinal Cord Injury and Regulates Microglial Migration. Front Pharmacol. 2021;12:729524 pubmed publisher
  3. Jeong D, Kim H, Kim H, Kang M, Jung H, Oh Y, et al. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. elife. 2021;10: pubmed publisher
  4. West J, Austin E, Rizzi E, Yan L, Tanjore H, Crabtree A, et al. KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models. Int J Mol Sci. 2021;22: pubmed publisher
  5. GUTTIKONDA S, Sikkema L, Tchieu J, Saurat N, Walsh R, Harschnitz O, et al. Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease. Nat Neurosci. 2021;24:343-354 pubmed publisher
  6. Jin X, Morro B, Tørresen O, Moiche V, Solbakken M, Jakobsen K, et al. Innovation in Nucleotide-Binding Oligomerization-Like Receptor and Toll-Like Receptor Sensing Drives the Major Histocompatibility Complex-II Free Atlantic Cod Immune System. Front Immunol. 2020;11:609456 pubmed publisher
  7. Mathew D, Giles J, Baxter A, Greenplate A, Wu J, Alanio C, et al. Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions. bioRxiv. 2020;: pubmed publisher
  8. Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
  9. Ahn J, Kim D, Park J, Lee T, Lee H, Won M, et al. Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia. Int J Mol Med. 2019;44:939-948 pubmed publisher
  10. Meckiff B, Ladell K, McLaren J, Ryan G, Leese A, James E, et al. Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells. J Immunol. 2019;203:1276-1287 pubmed publisher
  11. Lau E, Carroll E, Callender L, Hood G, Berryman V, Pattrick M, et al. Type 2 diabetes is associated with the accumulation of senescent T cells. Clin Exp Immunol. 2019;197:205-213 pubmed publisher
  12. Cassetta L, Fragkogianni S, Sims A, Swierczak A, Forrester L, Zhang H, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. 2019;35:588-602.e10 pubmed publisher
  13. Remmerswaal E, Hombrink P, Nota B, Pircher H, ten Berge I, van Lier R, et al. Expression of IL-7Rα and KLRG1 defines functionally distinct CD8+ T-cell populations in humans. Eur J Immunol. 2019;49:694-708 pubmed publisher
  14. Collins P, Cella M, Porter S, Li S, Gurewitz G, Hong H, et al. Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells. Cell. 2019;176:348-360.e12 pubmed publisher
  15. Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed publisher
  16. Jeong J, Hong S, Kwon O, Ghang B, Hwang I, Kim Y, et al. CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis. Front Immunol. 2017;8:1260 pubmed publisher
  17. Molnar C, Scherer A, Baraliakos X, de Hooge M, Micheroli R, Exer P, et al. TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort. Ann Rheum Dis. 2018;77:63-69 pubmed publisher
  18. Tong A, Hashem H, Eid S, Allen F, Kingsley D, Huang A. Adoptive natural killer cell therapy is effective in reducing pulmonary metastasis of Ewing sarcoma. Oncoimmunology. 2017;6:e1303586 pubmed publisher
  19. See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  20. Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
  21. Wouters K, Gaens K, Bijnen M, Verboven K, Jocken J, Wetzels S, et al. Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue. Sci Rep. 2017;7:42665 pubmed publisher
  22. Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
  23. Sellgren C, Sheridan S, Gracias J, Xuan D, Fu T, Perlis R. Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors. Mol Psychiatry. 2017;22:170-177 pubmed publisher
  24. Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
  25. Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
  26. Pachnio A, Ciáurriz M, Begum J, Lal N, Zuo J, Beggs A, et al. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016;12:e1005832 pubmed publisher
  27. Pinilla Vera M, Xiong Z, Zhao Y, Zhao J, Donahoe M, Barge S, et al. Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. PLoS ONE. 2016;11:e0159329 pubmed publisher
  28. Ding X, Pan L, Wang Y, Xu Q. Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice. Int J Mol Med. 2016;37:703-15 pubmed publisher
  29. Waschbisch A, Schröder S, Schraudner D, Sammet L, Weksler B, Melms A, et al. Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System. J Immunol. 2016;196:1558-67 pubmed publisher
  30. McCausland M, Juchnowski S, Zidar D, Kuritzkes D, Andrade A, Sieg S, et al. Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy. PLoS ONE. 2015;10:e0139474 pubmed publisher
  31. Zsiros E, Duttagupta P, Dangaj D, Li H, Frank R, Garrabrant T, et al. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. Clin Cancer Res. 2015;21:2840-50 pubmed publisher
  32. Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  33. Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed publisher
  34. Cannon J, Sharma G, Sloan G, Dimitropoulou C, Baker R, Mazzoli A, et al. Leptin regulates CD16 expression on human monocytes in a sex-specific manner. Physiol Rep. 2014;2: pubmed publisher
  35. Staumont Sallé D, Fleury S, Lazzari A, Molendi Coste O, Hornez N, Lavogiez C, et al. CX?CL1 (fractalkine) and its receptor CX?CR1 regulate atopic dermatitis by controlling effector T cell retention in inflamed skin. J Exp Med. 2014;211:1185-96 pubmed publisher
  36. Wilson E, Singh A, Hullsiek K, Gibson D, Henry W, Lichtenstein K, et al. Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection. J Infect Dis. 2014;210:1396-406 pubmed publisher
  37. Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed publisher
  38. Fung E, Esposito L, Todd J, Wicker L. Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry. Nat Protoc. 2010;5:357-70 pubmed publisher