This is a Validated Antibody Database (VAD) review about human CUX1, based on 17 published articles (read how Labome selects the articles), using CUX1 antibody in all methods. It is aimed to help Labome visitors find the most suited CUX1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CUX1 synonym: CASP; CDP; CDP/Cut; CDP1; COY1; CUTL1; CUX; Clox; Cux/CDP; GDDI; GOLIM6; Nbla10317; p100; p110; p200; p75

Knockout validation
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; mouse; loading ...; fig 4d
  • western blot; human; loading ...; fig 2b
Invitrogen CUX1 antibody (Invitrogen, PA5-30003) was used in immunocytochemistry knockout validation on mouse samples (fig 4d) and in western blot on human samples (fig 2b). J Neurosci (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 3s4e
  • immunocytochemistry; African green monkey; 1:500; loading ...; fig 3s4e
Santa Cruz Biotechnology CUX1 antibody (Santa Cruz, sc-514008) was used in immunocytochemistry on human samples at 1:500 (fig 3s4e) and in immunocytochemistry on African green monkey samples at 1:500 (fig 3s4e). elife (2021) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 1c
Santa Cruz Biotechnology CUX1 antibody (Santa, sc-514008) was used in western blot on human samples at 1:1000 (fig 1c). EMBO Mol Med (2019) ncbi
Santa Cruz Biotechnology CUX1 antibody (Santa Cruz, M-222) was used . Science (2017) ncbi
  • immunohistochemistry; mouse; loading ...; fig s1d
Santa Cruz Biotechnology CUX1 antibody (SantaCruz, SC-13024) was used in immunohistochemistry on mouse samples (fig s1d). Cell (2017) ncbi
mouse monoclonal
  • ChIP-Seq; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology CUX1 antibody (Santa Cruz, sc-514008) was used in ChIP-Seq on human samples (fig 5a) and in western blot on human samples (fig 4a). Nucleic Acids Res (2017) ncbi
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1a
Santa Cruz Biotechnology CUX1 antibody (Santa Cruz Biotechnology Inc, sc-13024) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 1a). J Neurosci (2017) ncbi
  • immunocytochemistry; human; 1:100; loading ...; fig st4
In order to describe a small-molecule method to improve induction of early-born cortical neurons, Santa Cruz Biotechnology CUX1 antibody (Santa Cruz, Sc-13024) was used in immunocytochemistry on human samples at 1:100 (fig st4). Nat Biotechnol (2017) ncbi
  • immunohistochemistry; mouse; 1:100; loading ...; fig s9
In order to demonstrate that missense mutations in NEDD4L result in periventricular nodular heterotopia associated with toe syndactyly, cleft palate, and neurodevelopmental delay, Santa Cruz Biotechnology CUX1 antibody (Santa cruz, sc-13024) was used in immunohistochemistry on mouse samples at 1:100 (fig s9). Nat Genet (2016) ncbi
Santa Cruz Biotechnology CUX1 antibody (Santa Cruz, sc13024) was used . Nat Commun (2016) ncbi
Abcam
mouse monoclonal (CL5275)
  • western blot; mouse; 1:500; loading ...; fig 4g
Abcam CUX1 antibody (Abcam, ab242194) was used in western blot on mouse samples at 1:500 (fig 4g). Development (2021) ncbi
mouse monoclonal (2A10)
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 4h
Abcam CUX1 antibody (Abcam, ab54583) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4h). Front Immunol (2021) ncbi
mouse monoclonal (2A10)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2h
Abcam CUX1 antibody (Abcam, ab54583) was used in immunohistochemistry on mouse samples at 1:100 (fig 2h). Neurol Neuroimmunol Neuroinflamm (2021) ncbi
mouse monoclonal (2A10)
  • immunohistochemistry - frozen section; human; 1:100; loading ...; fig 5j
Abcam CUX1 antibody (Abcam, ab54583) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig 5j). Nat Neurosci (2019) ncbi
mouse monoclonal (2A10)
  • immunohistochemistry - frozen section; human; 1:350; loading ...; fig st1
In order to compare the gene expression in individual cells isolated from human brain organoids, Abcam CUX1 antibody (Abcam, AB54583) was used in immunohistochemistry - frozen section on human samples at 1:350 (fig st1). Nature (2017) ncbi
Abnova
mouse monoclonal (2A10)
  • immunohistochemistry - frozen section; human; loading ...; fig 3a
Abnova CUX1 antibody (Abnova, H00001523-M01) was used in immunohistochemistry - frozen section on human samples (fig 3a). Science (2019) ncbi
mouse monoclonal (2A10)
  • western blot; human; loading ...; fig 1c
Abnova CUX1 antibody (Novus Biologicals, 2A10) was used in western blot on human samples (fig 1c). Curr Cancer Drug Targets (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry knockout validation; mouse; loading ...; fig 4d
  • western blot; human; loading ...; fig 2b
Invitrogen CUX1 antibody (Invitrogen, PA5-30003) was used in immunocytochemistry knockout validation on mouse samples (fig 4d) and in western blot on human samples (fig 2b). J Neurosci (2018) ncbi
Articles Reviewed
  1. Wittmann M, Katada S, Sock E, Kirchner P, Ekici A, Wegner M, et al. scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development. 2021;148: pubmed publisher
  2. Pozo Rodrig xe1 lvarez A, Ollaranta R, Skoog J, Pekny M, Pekna M. Hyperactive Behavior and Altered Brain Morphology in Adult Complement C3a Receptor Deficient Mice. Front Immunol. 2021;12:604812 pubmed publisher
  3. Schörnig M, Ju X, Fast L, Ebert S, Weigert A, Kanton S, et al. Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes. elife. 2021;10: pubmed publisher
  4. . Placental transfer of NMDAR antibodies causes reversible alterations in mice. Neurol Neuroimmunol Neuroinflamm. 2021;8: pubmed publisher
  5. Sun A, Yuan Q, Fukuda M, Yu W, Yan H, Lim G, et al. Potassium channel dysfunction in human neuronal models of Angelman syndrome. Science. 2019;366:1486-1492 pubmed publisher
  6. Li H, Yang F, Hu A, Wang X, Fang E, Chen Y, et al. Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression. EMBO Mol Med. 2019;11:e10835 pubmed publisher
  7. Giandomenico S, Mierau S, Gibbons G, Wenger L, Masullo L, Sit T, et al. Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. Nat Neurosci. 2019;22:669-679 pubmed publisher
  8. Kuliyev E, Gingras S, Guy C, Howell S, Vogel P, Pelletier S. Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability. J Neurosci. 2018;38:2615-2630 pubmed publisher
  9. Burga A, Wang W, Ben David E, Wolf P, Ramey A, Verdugo C, et al. A genetic signature of the evolution of loss of flight in the Galapagos cormorant. Science. 2017;356: pubmed publisher
  10. del Toro D, Ruff T, Cederfjäll E, Villalba A, Seyit Bremer G, Borrell V, et al. Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Cell. 2017;169:621-635.e16 pubmed publisher
  11. Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed publisher
  12. Arthur R, An N, Khan S, McNerney M. The haploinsufficient tumor suppressor, CUX1, acts as an analog transcriptional regulator that controls target genes through distal enhancers that loop to target promoters. Nucleic Acids Res. 2017;45:6350-6361 pubmed publisher
  13. Ha S, Tripathi P, Mihalas A, Hevner R, Beier D. C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus. J Neurosci. 2017;37:960-971 pubmed publisher
  14. Qi Y, Zhang X, Renier N, Wu Z, Atkin T, Sun Z, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017;35:154-163 pubmed publisher
  15. Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed publisher
  16. Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
  17. Nguyen H, Kadam P, Helkin A, Cao K, Wu S, Samara G, et al. MT1-MMP Activation of TGF-? Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer. Curr Cancer Drug Targets. 2016;16:618-30 pubmed