This is a Validated Antibody Database (VAD) review about human CUL4A, based on 13 published articles (read how Labome selects the articles), using CUL4A antibody in all methods. It is aimed to help Labome visitors find the most suited CUL4A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (EPR3198)
  • western blot; human; loading ...; fig s1d
Abcam CUL4A antibody (Abcam, 92554) was used in western blot on human samples (fig s1d). Cell Death Differ (2022) ncbi
domestic rabbit monoclonal (EPR3198)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2e
Abcam CUL4A antibody (Abcam, EPR3198) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2e). BMC Cancer (2017) ncbi
domestic rabbit monoclonal (EPR3198)
  • western blot; human; loading ...; fig 1d
Abcam CUL4A antibody (Abcam, EPR3198) was used in western blot on human samples (fig 1d). Biochem Biophys Res Commun (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-11)
  • western blot; human; 1:1000; loading ...; fig 5c
Santa Cruz Biotechnology CUL4A antibody (SantaCruz, sc-377188) was used in western blot on human samples at 1:1000 (fig 5c). elife (2020) ncbi
mouse monoclonal (H-11)
  • western blot; human; 1:1000; loading ...; fig s4b
Santa Cruz Biotechnology CUL4A antibody (Santa Cruz, sc-377188) was used in western blot on human samples at 1:1000 (fig s4b). Nat Commun (2018) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...
In order to find that a subset of SLC25A46 interacts with mitochondrial dynamics components and the MICOS complex, Invitrogen CUL4A antibody (Thermo Fisher, PA5-29857) was used in western blot on human samples . Mol Biol Cell (2017) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7s1a
Cell Signaling Technology CUL4A antibody (CST, 2699s) was used in western blot on human samples (fig 7s1a). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology CUL4A antibody (CST, 2699) was used in western blot on human samples (fig 2c). Genes Dev (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology CUL4A antibody (Cell Signaling, 2699) was used in western blot on human samples at 1:1000 (fig 3e). Science (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2b
In order to identify and characterize an inhibitor of the COP9 signalosome, Cell Signaling Technology CUL4A antibody (Cell Signaling, 2699) was used in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s3b
In order to determine the rotavirus NSP1-host protein interaction network, Cell Signaling Technology CUL4A antibody (CST, 2699) was used in western blot on human samples (fig s3b). PLoS Pathog (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
In order to use knockout mice to determine the role of cereblon in T cells, Cell Signaling Technology CUL4A antibody (Cell Signaling, 2699) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 6s1
In order to study the cullin-RING ubiquitin ligase deneddylation cycle and COP9-signalosome activation by structural and kinetic analysis, Cell Signaling Technology CUL4A antibody (Cell Signaling, 2699) was used in western blot on human samples (fig 6s1). elife (2016) ncbi
Articles Reviewed
  1. Fan Y, Hou T, Dan W, Zhu Y, Liu B, Wei Y, et al. ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. Cell Death Differ. 2022;: pubmed publisher
  2. Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, et al. AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions. elife. 2020;9: pubmed publisher
  3. Pech M, Fong L, Villalta J, Chan L, Kharbanda S, O Brien J, et al. Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance. elife. 2019;8: pubmed publisher
  4. Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
  5. Morgan M, Rickels R, Collings C, He X, Cao K, Herz H, et al. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev. 2017;31:2003-2014 pubmed publisher
  6. Huang G, Liu T, Weng S, You H, Wei Y, Chen C, et al. CUL4A overexpression as an independent adverse prognosticator in intrahepatic cholangiocarcinoma. BMC Cancer. 2017;17:395 pubmed publisher
  7. Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting T, et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science. 2017;356: pubmed publisher
  8. Steffen J, Vashisht A, Wan J, Jen J, Claypool S, Wohlschlegel J, et al. Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. Mol Biol Cell. 2017;28:600-612 pubmed publisher
  9. Han X, Fang Z, Wang H, Jiao R, Zhou J, Fang N. CUL4A functions as an oncogene in ovarian cancer and is directly regulated by miR-494. Biochem Biophys Res Commun. 2016;480:675-681 pubmed publisher
  10. Schlierf A, Altmann E, Quancard J, Jefferson A, Assenberg R, Renatus M, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016;7:13166 pubmed publisher
  11. Ding S, Mooney N, Li B, Kelly M, Feng N, Loktev A, et al. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016;12:e1005929 pubmed publisher
  12. Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed publisher
  13. Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher