This is a Validated Antibody Database (VAD) review about human CUL3, based on 13 published articles (read how Labome selects the articles), using CUL3 antibody in all methods. It is aimed to help Labome visitors find the most suited CUL3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CUL3 synonym: CUL-3; PHA2E

Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 3c, s3
Abcam CUL3 antibody (Abcam, ab194584) was used in immunocytochemistry on human samples (fig 3c, s3). Cell Cycle (2019) ncbi
domestic rabbit monoclonal (EPR3196Y)
  • RNA immunoprecipitation; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3e
Abcam CUL3 antibody (Abcam, EPR3196Y) was used in RNA immunoprecipitation on human samples (fig 3d) and in western blot on human samples (fig 3e). Oncogene (2016) ncbi
domestic rabbit monoclonal (EPR3195)
  • western blot; human; fig 2
Abcam CUL3 antibody (Abcam, ab108407) was used in western blot on human samples (fig 2). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (EPR3196Y)
  • western blot; rat; loading ...; fig 1c
In order to study the Cdk5-Nrf2 pathway and its implication in neuronal protection against ROS., Abcam CUL3 antibody (Abcam, ab75851) was used in western blot on rat samples (fig 1c). Cell Death Differ (2015) ncbi
domestic rabbit monoclonal (EPR3196Y)
  • western blot; human; fig s1e
In order to demonstrate that G-protein-coupled receptors modulate the levels of Atg14L through ZBTB16, Abcam CUL3 antibody (abcam, ab75851) was used in western blot on human samples (fig s1e). elife (2015) ncbi
domestic rabbit monoclonal (EPR3196Y)
  • western blot; human
Abcam CUL3 antibody (Abcam, ab75851) was used in western blot on human samples . PLoS ONE (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-8)
  • immunoprecipitation; human; loading ...; fig 1f
  • immunohistochemistry; human; loading ...; fig 2g
  • western blot; human; loading ...; fig 2e
Santa Cruz Biotechnology CUL3 antibody (Santa Cruz, sc-166110) was used in immunoprecipitation on human samples (fig 1f), in immunohistochemistry on human samples (fig 2g) and in western blot on human samples (fig 2e). Genes Dev (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1e
Cell Signaling Technology CUL3 antibody (Cell Signaling, 2759) was used in western blot on human samples (fig 1e). Cell Death Differ (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1h
Cell Signaling Technology CUL3 antibody (Cell Signaling, 2759) was used in western blot on human samples at 1:1000 (fig 1h). Mol Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1k
Cell Signaling Technology CUL3 antibody (Cell Signaling, 2759) was used in western blot on human samples at 1:1000 (fig 1k). Adv Sci (Weinh) (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s4b
Cell Signaling Technology CUL3 antibody (Cell Signaling, 2759) was used in western blot on human samples at 1:1000 (fig s4b). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology CUL3 antibody (Cell Signaling, 2759) was used in western blot on human samples at 1:1000 (fig 2b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
In order to determine the rotavirus NSP1-host protein interaction network, Cell Signaling Technology CUL3 antibody (CST, 2759) was used in western blot on human samples (fig 2b). PLoS Pathog (2016) ncbi
Articles Reviewed
  1. Fan Y, Hou T, Dan W, Zhu Y, Liu B, Wei Y, et al. ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. Cell Death Differ. 2022;: pubmed publisher
  2. Jiang Q, Zheng N, Bu L, Zhang X, Zhang X, Wu Y, et al. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Mol Cancer. 2021;20:100 pubmed publisher
  3. Su S, Chen J, Jiang Y, Wang Y, Vital T, Zhang J, et al. SPOP and OTUD7A Control EWS-FLI1 Protein Stability to Govern Ewing Sarcoma Growth. Adv Sci (Weinh). 2021;8:e2004846 pubmed publisher
  4. Chung D, Salsman J, Dellaire G. Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis. Cell Cycle. 2019;18:1135-1153 pubmed publisher
  5. Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
  6. Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher
  7. Ding S, Mooney N, Li B, Kelly M, Feng N, Loktev A, et al. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016;12:e1005929 pubmed publisher
  8. Zhang C, Liu J, Huang G, Zhao Y, Yue X, Wu H, et al. Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression. Genes Dev. 2016;30:1956-70 pubmed publisher
  9. Sakurai T, Isogaya K, Sakai S, Morikawa M, Morishita Y, Ehata S, et al. RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma. Oncogene. 2016;35:5000-9 pubmed publisher
  10. Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher
  11. Jimenez Blasco D, Santofimia Castaño P, Gonzalez A, Almeida A, Bolaños J. Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway. Cell Death Differ. 2015;22:1877-89 pubmed publisher
  12. Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, et al. G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. elife. 2015;4:e06734 pubmed publisher
  13. Manjarrez J, Sun L, Prince T, Matts R. Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex. PLoS ONE. 2014;9:e90054 pubmed publisher