This is a Validated Antibody Database (VAD) review about human CTH, based on 13 published articles (read how Labome selects the articles), using CTH antibody in all methods. It is aimed to help Labome visitors find the most suited CTH antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abnova
mouse monoclonal (2E12-1C10)
  • western blot knockout validation; mouse; fig 7
Abnova CTH antibody (Abnova, H00001491-M02) was used in western blot knockout validation on mouse samples (fig 7). J Biol Chem (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-1)
  • western blot; rat; 1:1000; loading ...; fig 3g
Santa Cruz Biotechnology CTH antibody (Santa Cruz, sc-374249) was used in western blot on rat samples at 1:1000 (fig 3g). Int J Nanomedicine (2019) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:100; loading ...; fig 2a
Santa Cruz Biotechnology CTH antibody (Santa Cruz, sc-365382) was used in western blot on human samples at 1:100 (fig 2a). Int J Oncol (2019) ncbi
mouse monoclonal (F-1)
  • immunocytochemistry; Chlamydomonas reinhardtii; 1:200
  • western blot; Chlamydomonas reinhardtii; 1:500
Santa Cruz Biotechnology CTH antibody (Santa Cruz Biotechnology, SC-374249) was used in immunocytochemistry on Chlamydomonas reinhardtii samples at 1:200 and in western blot on Chlamydomonas reinhardtii samples at 1:500. Endocrinology (2015) ncbi
mouse monoclonal (F-1)
  • immunohistochemistry - frozen section; mouse
  • western blot; mouse
In order to test if H2S supplementation reduces MMP-9-induced extracellular matrix remodeling and dysfunction in diabetic kidney, Santa Cruz Biotechnology CTH antibody (Santa Cruz Biotechnology, sc-374249) was used in immunohistochemistry - frozen section on mouse samples and in western blot on mouse samples . Nitric Oxide (2015) ncbi
mouse monoclonal (F-1)
  • western blot; mouse; fig 1
Santa Cruz Biotechnology CTH antibody (Santa Cruz, sc-374249) was used in western blot on mouse samples (fig 1). Int J Mol Sci (2015) ncbi
Proteintech Group
mouse monoclonal (2C7F9)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
Proteintech Group CTH antibody (ProteinTech, 60234-1-Ig) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Int J Oncol (2019) ncbi
mouse monoclonal (2C7F9)
  • immunohistochemistry; dogs; 1:500; loading ...; fig 6
  • western blot; dogs; 1:1000; loading ...; fig 2b
  • immunohistochemistry; human; 1:500; loading ...; fig 6
  • western blot; human; 1:1000; loading ...; fig 2b
Proteintech Group CTH antibody (Proteintech, 60234-C1-Ig) was used in immunohistochemistry on dogs samples at 1:500 (fig 6), in western blot on dogs samples at 1:1000 (fig 2b), in immunohistochemistry on human samples at 1:500 (fig 6) and in western blot on human samples at 1:1000 (fig 2b). Exp Eye Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5d
In order to test if H2S and its metabolites alter endothelial permeability, Proteintech Group CTH antibody (Proteintech, 12217-1-AP) was used in western blot on human samples at 1:1000 (fig 5d). Redox Biol (2016) ncbi
Abnova
mouse monoclonal (2E12-1C10)
  • western blot; mouse; 1:2000
Abnova CTH antibody (Abnova, H00001491-M02) was used in western blot on mouse samples at 1:2000. Biol Open (2015) ncbi
mouse monoclonal (4E1-1B7)
  • western blot; mouse; fig 5
Abnova CTH antibody (Abnova, H00001491-M01) was used in western blot on mouse samples (fig 5). Int J Mol Sci (2015) ncbi
mouse monoclonal (S51)
  • western blot; human; 1:7000
Abnova CTH antibody (Abnova, H00001491-M03) was used in western blot on human samples at 1:7000. Nitric Oxide (2015) ncbi
mouse monoclonal (4E1-1B7)
  • western blot; mouse
Abnova CTH antibody (Abnova, H00001491-M01) was used in western blot on mouse samples . Pharmacol Res (2014) ncbi
mouse monoclonal (2E12-1C10)
  • western blot knockout validation; mouse; fig 7
Abnova CTH antibody (Abnova, H00001491-M02) was used in western blot knockout validation on mouse samples (fig 7). J Biol Chem (2012) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2a
In order to assess the effects of sub-cytotoxic exposure to formaldehyde on skin cells, Invitrogen CTH antibody (Thermo-Scientific, PA5-29725) was used in western blot on human samples (fig 2a). Toxicol Appl Pharmacol (2016) ncbi
Articles Reviewed
  1. Tran B, Yu Y, Chang L, Tan B, Jia W, Xiong Y, et al. A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway. Int J Nanomedicine. 2019;14:10061-10077 pubmed publisher
  2. Wang L, Shi H, Liu Y, Zhang W, Duan X, Li M, et al. Cystathionine‑γ‑lyase promotes the metastasis of breast cancer via the VEGF signaling pathway. Int J Oncol. 2019;55:473-487 pubmed publisher
  3. Badiei A, Sudharsan R, Santana E, Dunaief J, Aguirre G. Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina. Exp Eye Res. 2019;181:72-84 pubmed publisher
  4. Lee E, Kim H, Lee M, Jin S, Hong S, Ahn S, et al. Cystathionine metabolic enzymes play a role in the inflammation resolution of human keratinocytes in response to sub-cytotoxic formaldehyde exposure. Toxicol Appl Pharmacol. 2016;310:185-194 pubmed publisher
  5. Yuan S, Pardue S, Shen X, Alexander J, Orr A, Kevil C. Hydrogen sulfide metabolism regulates endothelial solute barrier function. Redox Biol. 2016;9:157-166 pubmed publisher
  6. Jiang H, Hurt K, Breen K, Stabler S, Allen R, Orlicky D, et al. Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap. Biol Open. 2015;4:1154-62 pubmed publisher
  7. Li J, Li Q, Du H, Wang Y, You S, Wang F, et al. Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. Int J Mol Sci. 2015;16:12560-77 pubmed publisher
  8. Lechuga T, Zhang H, Sheibani L, Karim M, Jia J, Magness R, et al. Estrogen Replacement Therapy in Ovariectomized Nonpregnant Ewes Stimulates Uterine Artery Hydrogen Sulfide Biosynthesis by Selectively Up-Regulating Cystathionine β-Synthase Expression. Endocrinology. 2015;156:2288-98 pubmed publisher
  9. Kundu S, Pushpakumar S, Sen U. MMP-9- and NMDA receptor-mediated mechanism of diabetic renovascular remodeling and kidney dysfunction: hydrogen sulfide is a key modulator. Nitric Oxide. 2015;46:172-85 pubmed publisher
  10. Veeranki S, Tyagi S. Mechanisms of hyperhomocysteinemia induced skeletal muscle myopathy after ischemia in the CBS-/+ mouse model. Int J Mol Sci. 2015;16:1252-65 pubmed publisher
  11. Ohmura M, Hishiki T, Yamamoto T, Nakanishi T, Kubo A, Tsuchihashi K, et al. Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry. Nitric Oxide. 2015;46:102-13 pubmed publisher
  12. Xu Y, Du H, Li J, Xu R, Wang Y, You S, et al. Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage. Pharmacol Res. 2014;87:18-25 pubmed publisher
  13. Dickhout J, Carlisle R, Jerome D, Mohammed Ali Z, Jiang H, Yang G, et al. Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism. J Biol Chem. 2012;287:7603-14 pubmed publisher