This is a Validated Antibody Database (VAD) review about human CRX, based on 8 published articles (read how Labome selects the articles), using CRX antibody in all methods. It is aimed to help Labome visitors find the most suited CRX antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CRX synonym: CORD2; CRD; LCA7; OTX3

Abnova
mouse monoclonal (4G11)
  • immunohistochemistry; human; 1:800; fig 2f
Abnova CRX antibody (Abnova, H000014-06-M02) was used in immunohistochemistry on human samples at 1:800 (fig 2f). Stem Cells (2021) ncbi
mouse monoclonal (4G11)
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig 1s1j
Abnova CRX antibody (Abnova, H00001406-M02) was used in immunohistochemistry - frozen section on mouse samples at 1:2000 (fig 1s1j). elife (2020) ncbi
mouse monoclonal (4G11)
  • immunohistochemistry - frozen section; human; 1:5000; loading ...; fig s1a
Abnova CRX antibody (Abnova, H00001406-M02) was used in immunohistochemistry - frozen section on human samples at 1:5000 (fig s1a). Int J Mol Sci (2020) ncbi
mouse monoclonal (4G11)
  • immunocytochemistry; human; 1:500; fig 2f
Abnova CRX antibody (Abnova, H00001406-M02) was used in immunocytochemistry on human samples at 1:500 (fig 2f). Lab Invest (2015) ncbi
mouse monoclonal (4G11)
  • immunocytochemistry; human; 1:100
In order to describe a method to differentiate human pluripotent stem cells into retinal cell types, Abnova CRX antibody (Abnova, H00001406-M02) was used in immunocytochemistry on human samples at 1:100. Curr Protoc Stem Cell Biol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-9)
  • western blot; human; loading ...; fig 1b
Santa Cruz Biotechnology CRX antibody (SantaCruz, sc-377138) was used in western blot on human samples (fig 1b). Cell Biol Int (2018) ncbi
R&D Systems
domestic sheep polyclonal
  • immunocytochemistry; human; fig 2b
R&D Systems CRX antibody (R&D Systems, AF7085) was used in immunocytochemistry on human samples (fig 2b). Mol Ther Methods Clin Dev (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:250; loading ...; fig 3b
MilliporeSigma CRX antibody (Sigma, HPA036762) was used in immunohistochemistry on mouse samples at 1:250 (fig 3b). Eneuro (2021) ncbi
Articles Reviewed
  1. Pensieri P, Mantilleri A, Plassard D, Furukawa T, Moya K, Prochiantz A, et al. Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia. Eneuro. 2021;8: pubmed publisher
  2. Salas A, Duarri A, Fontrodona L, Ram xed rez D, Badia A, Isla Magran xe9 H, et al. Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration. Mol Ther Methods Clin Dev. 2021;20:688-702 pubmed publisher
  3. Cuevas E, Holder D, Alshehri A, Tr xe9 guier J, Lakowski J, Sowden J. NRL-/- gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors. Stem Cells. 2021;39:414-428 pubmed publisher
  4. Vigouroux R, Cesar Q, Chedotal A, Nguyen Ba Charvet K. Revisiting the role of Dcc in visual system development with a novel eye clearing method. elife. 2020;9: pubmed publisher
  5. Garita Hernandez M, Routet F, Guibbal L, Khabou H, Toualbi L, Riancho L, et al. AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2020;21: pubmed publisher
  6. Fukuda T, Ishizawa Y, Donai K, Sugano E, Tomita H. The poly-cistronic expression of four transcriptional factors (CRX, RAX, NEURO-D, OTX2) in fibroblasts via retro- or lentivirus causes partial reprogramming into photoreceptor cells. Cell Biol Int. 2018;42:608-614 pubmed publisher
  7. Khan M, Walters L, Li Q, Thomas D, Miller J, Zhang Q, et al. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma. Lab Invest. 2015;95:1278-90 pubmed publisher
  8. Ohlemacher S, Iglesias C, Sridhar A, Gamm D, Meyer J. Generation of highly enriched populations of optic vesicle-like retinal cells from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 2015;32:1H.8.1-20 pubmed publisher