This is a Validated Antibody Database (VAD) review about human CRTH2, based on 22 published articles (read how Labome selects the articles), using CRTH2 antibody in all methods. It is aimed to help Labome visitors find the most suited CRTH2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CRTH2 synonym: CD294; CRTH2; DL1R; DP2; GPR44

BioLegend
rat monoclonal (BM16)
  • flow cytometry; human; 1:50; loading ...; fig 4d
BioLegend CRTH2 antibody (Biolegend, BM16) was used in flow cytometry on human samples at 1:50 (fig 4d). Nat Commun (2021) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; 1:40; loading ...; fig 1s1f
BioLegend CRTH2 antibody (Biolegend, 350126) was used in flow cytometry on human samples at 1:40 (fig 1s1f). elife (2020) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 1b, 1d
BioLegend CRTH2 antibody (Biolegend, BM16) was used in flow cytometry on human samples (fig 1b, 1d). Arthritis Res Ther (2020) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 3a
BioLegend CRTH2 antibody (BioLegend, BM16) was used in flow cytometry on human samples (fig 3a). J Exp Med (2018) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 1a
BioLegend CRTH2 antibody (BioLegend, BM16) was used in flow cytometry on human samples (fig 1a). PLoS ONE (2017) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 3a
BioLegend CRTH2 antibody (Biolegend, BM16) was used in flow cytometry on human samples (fig 3a). Proc Natl Acad Sci U S A (2017) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; fig 1a
In order to study the involvement of Notch signaling in NK cell lineage determination, BioLegend CRTH2 antibody (biolegend, BM16) was used in flow cytometry on human samples (fig 1a). J Immunol (2017) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig s4
In order to characterize innate lymphoid cell subpopulations isolated from patients with systemic sclerosis, BioLegend CRTH2 antibody (biolegend, BM16) was used in flow cytometry on human samples (fig s4). J Immunol (2016) ncbi
rat monoclonal (BM16)
BioLegend CRTH2 antibody (BioLegend, BM16) was used . Clin Cancer Res (2014) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; tbl 1
In order to study the effect of innate lymphoid cells on B cells, BioLegend CRTH2 antibody (Biolegend, BM16) was used in flow cytometry on human samples (tbl 1). Nat Immunol (2014) ncbi
Beckman Coulter
rat monoclonal (BM16)
  • flow cytometry; human; fig e1a
Beckman Coulter CRTH2 antibody (Beckman Coulter, BM16) was used in flow cytometry on human samples (fig e1a). J Allergy Clin Immunol (2018) ncbi
BD Biosciences
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig s1
BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in flow cytometry on human samples (fig s1). elife (2020) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; 1:50; loading ...; fig 1a
BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in flow cytometry on human samples at 1:50 (fig 1a). Nat Commun (2019) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig ex1
BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in flow cytometry on human samples (fig ex1). Nature (2019) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 1d
In order to report that autosomal recessive, partial Go-Ichi-Ni-San 1 deficiency impairs DNA replication and underlies intra-uterine and postnatal growth retardation, chronic neutropenia, and natural killer cell deficiency, BD Biosciences CRTH2 antibody (BD Pharmingen, BM16) was used in flow cytometry on human samples (fig 1d). J Clin Invest (2017) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig s1a
In order to study the differentiation of innate lymphoid cells, BD Biosciences CRTH2 antibody (BD Bioscience, 558042) was used in flow cytometry on human samples (fig s1a). Cell (2017) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...
In order to identify RLTPR in patients and determine the effects of these mutations on CD4 positive T cells, BD Biosciences CRTH2 antibody (BD, BM16) was used in flow cytometry on human samples . J Exp Med (2016) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences CRTH2 antibody (BD, 558042) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
rat monoclonal (BM16)
  • flow cytometry; human; loading ...; fig 1a
In order to discuss the importance of IL-5 positive Th2 cells to allergies, BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in flow cytometry on human samples (fig 1a). J Allergy Clin Immunol (2016) ncbi
rat monoclonal (BM16)
  • immunocytochemistry; human
In order to study the role of dendritic cells in relation to T cells, BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in immunocytochemistry on human samples . J Immunol (2014) ncbi
rat monoclonal (BM16)
  • flow cytometry; human
BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in flow cytometry on human samples . J Allergy Clin Immunol (2014) ncbi
rat monoclonal (BM16)
  • blocking or activating experiments; human; 10 ug/ml
BD Biosciences CRTH2 antibody (BD Biosciences, BM16) was used in blocking or activating experiments on human samples at 10 ug/ml. J Biol Chem (2013) ncbi
Articles Reviewed
  1. Ercolano G, Gomez Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, et al. PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nat Commun. 2021;12:2538 pubmed publisher
  2. Kasatskaya S, Ladell K, Egorov E, Miners K, Davydov A, Metsger M, et al. Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs. elife. 2020;9: pubmed publisher
  3. Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed publisher
  4. Ryu S, Lee E, Kim D, Kim Y, Chung D, Kim J, et al. Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis. Arthritis Res Ther. 2020;22:63 pubmed publisher
  5. Wang H, Shen L, Sun X, Liu F, Feng W, Jiang C, et al. Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity. Nat Commun. 2019;10:3254 pubmed publisher
  6. Ardain A, Domingo Gonzalez R, Das S, Kazer S, Howard N, Singh A, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019;: pubmed publisher
  7. Li N, van Unen V, Höllt T, Thompson A, van Bergen J, Pezzotti N, et al. Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine. J Exp Med. 2018;215:1383-1396 pubmed publisher
  8. Jeffery H, McDowell P, Lutz P, Wawman R, Roberts S, Bagnall C, et al. Human intrahepatic ILC2 are IL-13positive amphiregulinpositive and their frequency correlates with model of end stage liver disease score. PLoS ONE. 2017;12:e0188649 pubmed publisher
  9. Maric J, Ravindran A, Mazzurana L, Björklund Ã, Van Acker A, Rao A, et al. Prostaglandin E2 suppresses human group 2 innate lymphoid cell function. J Allergy Clin Immunol. 2018;141:1761-1773.e6 pubmed publisher
  10. Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed publisher
  11. Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed publisher
  12. Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
  13. Lim A, Li Y, Lopez Lastra S, Stadhouders R, Paul F, Casrouge A, et al. Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation. Cell. 2017;168:1086-1100.e10 pubmed publisher
  14. Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed
  15. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  16. Roan F, Stoklasek T, Whalen E, Molitor J, Bluestone J, Buckner J, et al. CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis. J Immunol. 2016;196:2051-2062 pubmed publisher
  17. Mitson Salazar A, Yin Y, Wansley D, Young M, Bolan H, Arceo S, et al. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function. J Allergy Clin Immunol. 2016;137:907-18.e9 pubmed publisher
  18. Yu C, Becker C, Metang P, Marches F, Wang Y, Toshiyuki H, et al. Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines. J Immunol. 2014;193:4335-43 pubmed publisher
  19. Renand A, Newbrough S, Wambre E, Delong J, Robinson D, Kwok W. Arginine kinase Pen m 2 as an important shrimp allergen recognized by TH2 cells. J Allergy Clin Immunol. 2014;134:1456-1459.e7 pubmed publisher
  20. Ohue Y, Kurose K, Mizote Y, Matsumoto H, Nishio Y, Isobe M, et al. Prolongation of overall survival in advanced lung adenocarcinoma patients with the XAGE1 (GAGED2a) antibody. Clin Cancer Res. 2014;20:5052-63 pubmed publisher
  21. Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  22. El Shazly A, Begon D, Kustermans G, Arafa M, Dortu E, Henket M, et al. Novel association between vasoactive intestinal peptide and CRTH2 receptor in recruiting eosinophils: a possible biochemical mechanism for allergic eosinophilic inflammation of the airways. J Biol Chem. 2013;288:1374-84 pubmed publisher