This is a Validated Antibody Database (VAD) review about human CRMP1, based on 25 published articles (read how Labome selects the articles), using CRMP1 antibody in all methods. It is aimed to help Labome visitors find the most suited CRMP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CRMP1 synonym: CRMP-1; DPYSL1; DRP-1; DRP1; ULIP-3

Knockout validation
Abcam
domestic rabbit monoclonal (EP14521)
  • western blot knockout validation; mouse; 1:5000; loading ...; fig e2-2a
Abcam CRMP1 antibody (Abcam, ab199722) was used in western blot knockout validation on mouse samples at 1:5000 (fig e2-2a). Eneuro (2022) ncbi
BD Biosciences
mouse monoclonal (22/Drp1)
  • western blot knockout validation; human; fig 1a
BD Biosciences CRMP1 antibody (BD Biosciences, noca) was used in western blot knockout validation on human samples (fig 1a). J Cell Biol (2016) ncbi
BD Biosciences
mouse monoclonal (22/Drp1)
  • western blot knockout validation; mouse; fig 9
BD Biosciences CRMP1 antibody (BD biosciences, 611738) was used in western blot knockout validation on mouse samples (fig 9). Nat Commun (2015) ncbi
Abcam
domestic rabbit monoclonal (EP14521)
  • western blot knockout validation; mouse; 1:5000; loading ...; fig e2-2a
Abcam CRMP1 antibody (Abcam, ab199722) was used in western blot knockout validation on mouse samples at 1:5000 (fig e2-2a). Eneuro (2022) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig s2b
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on mouse samples at 1:1000 (fig s2b). Mol Neurobiol (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1e
Cell Signaling Technology CRMP1 antibody (Cell Signaling Technology, 4867S) was used in western blot on mouse samples (fig 1e). Cells (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on mouse samples (fig 4b). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 7a
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on mouse samples at 1:1000 (fig 7a). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 7a
Cell Signaling Technology CRMP1 antibody (Cell Signaling Technology, 4867) was used in western blot on rat samples (fig 7a). Biomed Pharmacother (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
  • immunocytochemistry; pigs ; 1:1000; loading ...; fig 5d
Cell Signaling Technology CRMP1 antibody (Cell Signalling Technology, 4867) was used in western blot on mouse samples at 1:1000 (fig 5a) and in immunocytochemistry on pigs samples at 1:1000 (fig 5d). Redox Biol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 7a
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867s) was used in western blot on human samples at 1:1000 (fig 7a). J Biol Chem (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology CRMP1 antibody (Cell Signaling Technology, 4867) was used in western blot on mouse samples (fig 3e). Nature (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6e
Cell Signaling Technology CRMP1 antibody (Cell Signalling, 4867S) was used in western blot on mouse samples at 1:1000 (fig 6e). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on human samples (fig 6a). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • flow cytometry; human; fig 4
Cell Signaling Technology CRMP1 antibody (cell Signaling Tech, CST4867S) was used in flow cytometry on human samples (fig 4). Curr Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig sf3
In order to research the mechanisms of mitochondrial division, Cell Signaling Technology CRMP1 antibody (cell signalling, 4867S) was used in western blot on human samples (fig sf3). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on mouse samples . PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:500; loading ...; fig 10a
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in immunohistochemistry - paraffin section on rat samples at 1:500 (fig 10a). Front Cell Neurosci (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 4
In order to facilitate LIM kinase 2-mediated programmed necrotic neuronal death by mitochondrial translocation of high mobility group box 1, Cell Signaling Technology CRMP1 antibody (Cell signaling, 4867) was used in western blot on rat samples at 1:1000 (fig 4). Front Cell Neurosci (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s2a
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on human samples (fig s2a). J Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; fig 2
In order to elucidate how inhibition of vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation occurs by glucagon-like peptide 1, Cell Signaling Technology CRMP1 antibody (Cell Signalling, 4867) was used in western blot on rat samples at 1:500 (fig 2). Biochem Pharmacol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology CRMP1 antibody (Cell Signaling, 4867) was used in western blot on mouse samples (fig 5). J Immunol (2016) ncbi
BD Biosciences
mouse monoclonal (22/Drp1)
  • western blot; human; loading ...; fig 3d
BD Biosciences CRMP1 antibody (BD Bioscience, 611738) was used in western blot on human samples (fig 3d). J Clin Med (2019) ncbi
mouse monoclonal (22/Drp1)
  • western blot; mouse; loading ...; fig 4b
BD Biosciences CRMP1 antibody (BD Transduction, 611739) was used in western blot on mouse samples (fig 4b). Cardiovasc Res (2019) ncbi
mouse monoclonal (22/Drp1)
  • western blot; human; loading ...; fig 4e
BD Biosciences CRMP1 antibody (BD, 611738) was used in western blot on human samples (fig 4e). J Cell Biol (2016) ncbi
mouse monoclonal (22/Drp1)
  • western blot knockout validation; human; fig 1a
BD Biosciences CRMP1 antibody (BD Biosciences, noca) was used in western blot knockout validation on human samples (fig 1a). J Cell Biol (2016) ncbi
mouse monoclonal (22/Drp1)
  • western blot knockout validation; mouse; fig 9
BD Biosciences CRMP1 antibody (BD biosciences, 611738) was used in western blot knockout validation on mouse samples (fig 9). Nat Commun (2015) ncbi
mouse monoclonal (22/Drp1)
  • immunohistochemistry - paraffin section; human; fig 8
  • western blot; human; fig 4
BD Biosciences CRMP1 antibody (BD, 611738) was used in immunohistochemistry - paraffin section on human samples (fig 8) and in western blot on human samples (fig 4). Nat Neurosci (2015) ncbi
mouse monoclonal (22/Drp1)
  • western blot; mouse
  • immunocytochemistry; African green monkey
BD Biosciences CRMP1 antibody (BD Biosciences, 611738) was used in western blot on mouse samples and in immunocytochemistry on African green monkey samples . J Biol Chem (2014) ncbi
Articles Reviewed
  1. Li T, Sun Y, Zhang S, Xu Y, Li K, Xie C, et al. AIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia-Ischemia Injury. Mol Neurobiol. 2022;59:6613-6631 pubmed publisher
  2. Asano T, Nakamura H, Kawamoto Y, Tada M, Kimura Y, Takano H, et al. Inhibition of Crmp1 Phosphorylation at Ser522 Ameliorates Motor Function and Neuronal Pathology in Amyotrophic Lateral Sclerosis Model Mice. Eneuro. 2022;9: pubmed publisher
  3. Yoon Y, Go G, Yoon S, Lim J, Lee G, Lee J, et al. Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis. Cells. 2021;10: pubmed publisher
  4. Lee D, Kam M, Lee S, Lee H, Lee D. Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus. Cell Death Dis. 2020;11:204 pubmed publisher
  5. Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin S, et al. Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell Death Dis. 2020;11:77 pubmed publisher
  6. Shin H, Park H, Shin N, Kwon H, Yin Y, Hwang J, et al. Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis. J Clin Med. 2019;8: pubmed publisher
  7. Oka S, Chin A, Park J, Ikeda S, Mizushima W, Ralda G, et al. Thioredoxin-1 maintains mitochondrial function via mTOR signaling in the heart. Cardiovasc Res. 2019;: pubmed publisher
  8. Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  9. Li H, Feng J, Zhang Y, Feng J, Wang Q, Zhao S, et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway. Redox Biol. 2019;20:261-274 pubmed publisher
  10. De R, Sarkar S, Mazumder S, Debsharma S, Siddiqui A, Saha S, et al. Macrophage migration inhibitory factor regulates mitochondrial dynamics and cell growth of human cancer cell lines through CD74-NF-κB signaling. J Biol Chem. 2018;293:19740-19760 pubmed publisher
  11. Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  12. Velázquez Villegas L, Perino A, Lemos V, Zietak M, Nomura M, Pols T, et al. TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun. 2018;9:245 pubmed publisher
  13. Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  14. Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
  15. Lee J, Westrate L, Wu H, Page C, Voeltz G. Multiple dynamin family members collaborate to drive mitochondrial division. Nature. 2016;540:139-143 pubmed publisher
  16. El Sikhry H, Alsaleh N, Dakarapu R, Falck J, Seubert J. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. PLoS ONE. 2016;11:e0160380 pubmed publisher
  17. Ko A, Hyun H, Min S, Kim J. The Differential DRP1 Phosphorylation and Mitochondrial Dynamics in the Regional Specific Astroglial Death Induced by Status Epilepticus. Front Cell Neurosci. 2016;10:124 pubmed publisher
  18. Hyun H, Ko A, Kang T. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci. 2016;10:99 pubmed publisher
  19. Pryde K, Smith H, Chau K, Schapira A. PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy. J Cell Biol. 2016;213:163-71 pubmed publisher
  20. Otera H, Miyata N, Kuge O, Mihara K. Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling. J Cell Biol. 2016;212:531-44 pubmed publisher
  21. Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
  22. Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher
  23. Kang S, Fernandes Alnemri T, Rogers C, Mayes L, Wang Y, Dillon C, et al. Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nat Commun. 2015;6:7515 pubmed publisher
  24. Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher
  25. Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher