This is a Validated Antibody Database (VAD) review about human CR1, based on 14 published articles (read how Labome selects the articles), using CR1 antibody in all methods. It is aimed to help Labome visitors find the most suited CR1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CR1 synonym: C3BR; C4BR; CD35; complement receptor type 1; C3-binding protein; C3b/C4b receptor; CD35 antigen; Knops blood group antigen; complement component (3b/4b) receptor 1 (Knops blood group)

R&D Systems
mouse monoclonal (594708)
  • immunohistochemistry - paraffin section; human; 5000 ng/ml
  • immunocytochemistry; hamsters; 2000 ng/ml
R&D Systems CR1 antibody (R&D, MAB5748) was used in immunohistochemistry - paraffin section on human samples at 5000 ng/ml and in immunocytochemistry on hamsters samples at 2000 ng/ml. PLoS ONE (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-2)
  • immunocytochemistry; hamsters; 2000 ng/ml
  • immunohistochemistry - paraffin section; human; 4000 ng/ml
  • western blot; human
Santa Cruz Biotechnology CR1 antibody (Santa Cruz, sc-166329) was used in immunocytochemistry on hamsters samples at 2000 ng/ml, in immunohistochemistry - paraffin section on human samples at 4000 ng/ml and in western blot on human samples . PLoS ONE (2016) ncbi
BioLegend
mouse monoclonal (E11)
  • flow cytometry; human
BioLegend CR1 antibody (Biolegend, E11) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
Dako
mouse monoclonal (Ber-MAC-DRC)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 2
In order to characterize cases of follicular dendritic cell sarcoma, Dako CR1 antibody (Dako, Ber-MAC-DRC) was used in immunohistochemistry - paraffin section on human samples at 1:50 (tbl 2). Ann Diagn Pathol (2016) ncbi
mouse monoclonal (Ber-MAC-DRC)
  • immunohistochemistry; African green monkey; loading ...; fig 4c
In order to perform an enhanced embryo-fetal development investigation using pateclizumab in cynomolgus monkeys, Dako CR1 antibody (Dako, M0846) was used in immunohistochemistry on African green monkey samples (fig 4c). Reprod Toxicol (2016) ncbi
mouse monoclonal (Ber-MAC-DRC)
  • immunocytochemistry; human; 1:50; fig 2
In order to examine Cx43 channels in reactive follicular dendritic cell development and follicular lymphomas, Dako CR1 antibody (Dako, clone: Ber-Mac-DRC) was used in immunocytochemistry on human samples at 1:50 (fig 2). J Immunol Res (2015) ncbi
mouse monoclonal (Ber-MAC-DRC)
  • immunohistochemistry - paraffin section; human
In order to describe the features of plasma cells in patients with granulomatosis with polyangiitis, Dako CR1 antibody (Dako, Ber-MAC-DRC) was used in immunohistochemistry - paraffin section on human samples . Arthritis Res Ther (2014) ncbi
Beckman Coulter
mouse monoclonal (J3D3)
  • immunohistochemistry - paraffin section; human; 2000 ng/ml
Beckman Coulter CR1 antibody (Beckman-Coulter, IM0195) was used in immunohistochemistry - paraffin section on human samples at 2000 ng/ml. PLoS ONE (2016) ncbi
mouse monoclonal (J3D3)
  • flow cytometry; human; tbl 2
In order to test if flow cytometry can be used to find mantle cell lymphoma, Beckman Coulter CR1 antibody (Immunotech, J3.D3) was used in flow cytometry on human samples (tbl 2). Cytometry B Clin Cytom (2014) ncbi
mouse monoclonal (J3D3)
  • blocking or activating experiments; human
Beckman Coulter CR1 antibody (Beckman Coulter, J3D3) was used in blocking or activating experiments on human samples . PLoS ONE (2014) ncbi
BD Biosciences
mouse monoclonal (E11)
  • flow cytometry; human; 1:100; loading ...; fig s1a
BD Biosciences CR1 antibody (BD Pharmigen, E11) was used in flow cytometry on human samples at 1:100 (fig s1a). Science (2018) ncbi
mouse monoclonal (E11)
  • flow cytometry; human; loading ...; fig 5
BD Biosciences CR1 antibody (BD Pharmingen, E11) was used in flow cytometry on human samples (fig 5). Respir Res (2017) ncbi
mouse monoclonal (E11)
  • flow cytometry; human; loading ...
In order to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment, BD Biosciences CR1 antibody (BD Bioscience, E11) was used in flow cytometry on human samples . Sci Rep (2017) ncbi
mouse monoclonal (E11)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences CR1 antibody (BD, 559872) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (E11)
  • flow cytometry; human
In order to discuss the use of stem cells to treat Wiskott-Aldrich syndrome, BD Biosciences CR1 antibody (BD, E11) was used in flow cytometry on human samples . J Allergy Clin Immunol (2015) ncbi
mouse monoclonal (E11)
  • flow cytometry; human; fig S5
In order to use a new model which initiates alternate pathway activation on retinal pigment epithelial cells to investigate cell death, BD Biosciences CR1 antibody (BD Biosciences, clone E11) was used in flow cytometry on human samples (fig S5). Invest Ophthalmol Vis Sci (2014) ncbi
mouse monoclonal (E11)
  • flow cytometry; human
BD Biosciences CR1 antibody (BD Biosciences, E11) was used in flow cytometry on human samples . J Allergy Clin Immunol (2014) ncbi
Articles Reviewed
  1. Gruszczyk J, Kanjee U, Chan L, Menant S, Malleret B, Lim N, et al. Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax. Science. 2018;359:48-55 pubmed publisher
  2. Loi A, Hoonhorst S, van Aalst C, Langereis J, Kamp V, Sluis Eising S, et al. Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients. Respir Res. 2017;18:100 pubmed publisher
  3. Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  4. Agaimy A, Michal M, Hadravsky L, Michal M. Follicular dendritic cell sarcoma: clinicopathologic study of 15 cases with emphasis on novel expression of MDM2, somatostatin receptor 2A, and PD-L1. Ann Diagn Pathol. 2016;23:21-8 pubmed publisher
  5. Wang H, Schuetz C, Arima A, Chihaya Y, Weinbauer G, Habermann G, et al. Assessment of placental transfer and the effect on embryo-fetal development of a humanized monoclonal antibody targeting lymphotoxin-alpha in non-human primates. Reprod Toxicol. 2016;63:82-95 pubmed publisher
  6. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  7. Fonseca M, Chu S, Pierce A, Brubaker W, Hauhart R, Mastroeni D, et al. Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. PLoS ONE. 2016;11:e0149792 pubmed publisher
  8. Rajnai H, Teleki I, Kiszner G, Meggyesházi N, Balla P, Vancsik T, et al. Connexin 43 communication channels in follicular dendritic cell development and in follicular lymphomas. J Immunol Res. 2015;2015:528098 pubmed publisher
  9. Castiello M, Scaramuzza S, Pala F, Ferrua F, Uva P, Brigida I, et al. B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome. J Allergy Clin Immunol. 2015;136:692-702.e2 pubmed publisher
  10. Chovancová J, Bernard T, Stehlíková O, Sálek D, Janíková A, Mayer J, et al. Detection of Minimal Residual Disease in Mantle Cell Lymphoma. Establishment of Novel 8-Color Flow Cytometry Approach. Cytometry B Clin Cytom. 2014;: pubmed publisher
  11. Marinho C, Azeredo E, Torrentes Carvalho A, Marins Dos Santos A, Kubelka C, de Souza L, et al. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection. PLoS ONE. 2014;9:e102014 pubmed publisher
  12. Yang P, Baciu P, Kerrigan B, Etheridge M, Sung E, Toimil B, et al. Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress. Invest Ophthalmol Vis Sci. 2014;55:3012-21 pubmed publisher
  13. Mueller A, Brieske C, Schinke S, Csernok E, Gross W, Hasselbacher K, et al. Plasma cells within granulomatous inflammation display signs pointing to autoreactivity and destruction in granulomatosis with polyangiitis. Arthritis Res Ther. 2014;16:R55 pubmed publisher
  14. Lighaam L, Vermeulen E, Bleker T, Meijlink K, Aalberse R, Barnes E, et al. Phenotypic differences between IgG4+ and IgG1+ B cells point to distinct regulation of the IgG4 response. J Allergy Clin Immunol. 2014;133:267-70.e1-6 pubmed publisher