This is a Validated Antibody Database (VAD) review about human CPA1, based on 4 published articles (read how Labome selects the articles), using CPA1 antibody in all methods. It is aimed to help Labome visitors find the most suited CPA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CPA1 synonym: CPA; carboxypeptidase A1; carboxypeptidase A1 (pancreatic); pancreatic carboxypeptidase A

R&D Systems
goat polyclonal
  • immunohistochemistry; mouse; loading ...; fig 7f
In order to investigate the role of mitogen-activated protein kinase in pancreatitis, R&D Systems CPA1 antibody (R&D, af2765) was used in immunohistochemistry on mouse samples (fig 7f). Cell Mol Gastroenterol Hepatol (2017) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; tbl 3
In order to characterize a conditional knock out of ataxia telangiectasia-mutated as a mouse model of pancreatic ductal adenocarcinoma, R&D Systems CPA1 antibody (R+D Systems, AF2765) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (tbl 3). Nat Commun (2015) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig 4
In order to study inhibition of initiation of pancreatic ductal adenocarcinoma due to acinar differentiation determinant PTF1A, R&D Systems CPA1 antibody (R&D Systems, AF2765) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 4). elife (2015) ncbi
goat polyclonal
  • western blot; mouse; 1:1000
R&D Systems CPA1 antibody (R&D Systems, AF2765) was used in western blot on mouse samples at 1:1000. PLoS ONE (2015) ncbi
Articles Reviewed
  1. Halbrook C, Wen H, Ruggeri J, Takeuchi K, Zhang Y, di Magliano M, et al. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis. Cell Mol Gastroenterol Hepatol. 2017;3:99-118 pubmed publisher
  2. Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld F, et al. Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. Nat Commun. 2015;6:7677 pubmed publisher
  3. Krah N, De La O J, Swift G, Hoang C, Willet S, Chen Pan F, et al. The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. elife. 2015;4: pubmed publisher
  4. Hou Y, Ernst S, Stuenkel E, Lentz S, Williams J. Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS ONE. 2015;10:e0125596 pubmed publisher