This is a Validated Antibody Database (VAD) review about human CLSPN, based on 9 published articles (read how Labome selects the articles), using CLSPN antibody in all methods. It is aimed to help Labome visitors find the most suited CLSPN antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CLSPN synonym: claspin; claspin homolog

Santa Cruz Biotechnology
mouse monoclonal (B-6)
  • western blot; human; 1:200; loading ...; fig 1d
Santa Cruz Biotechnology CLSPN antibody (Santa Cruz Biotechnology, sc-376773) was used in western blot on human samples at 1:200 (fig 1d). Science (2017) ncbi
mouse monoclonal (B-6)
  • western blot; human
Santa Cruz Biotechnology CLSPN antibody (Santa Cruz Biotechnology, sc-376773) was used in western blot on human samples . J Virol (2014) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; 1:500
In order to study CDC26 phosphorylation and its effect on the tetratricopeptide repeat subcomplex of APC/C, Bethyl CLSPN antibody (Bethyl Laboratories Inc, A300-267A) was used in western blot on human samples at 1:500. PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2a
Bethyl CLSPN antibody (Bethyl, A300?C267A) was used in western blot on human samples (fig 2a). Nucleic Acids Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:2000
In order to show that the zinc finger E-box binding homeobox 1 regulates radiosensitivity and the DNA damage response in breast cancer cells, Bethyl CLSPN antibody (Bethyl, A300-265) was used in immunohistochemistry - frozen section on rat samples at 1:2000. Nat Cell Biol (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology CLSPN antibody (Cell Signaling, 2800) was used in western blot on human samples (fig 4). PLoS ONE (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 6
In order to compare the chemosensitizing effect of nucleoside analogues in cells derived from pancreatic cancer and in osteosarcoma-derived cells, Cell Signaling Technology CLSPN antibody (Cell signaling, 2800) was used in western blot on human samples (fig 6). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology CLSPN antibody (Cell Signaling Technology, 2800) was used in western blot on human samples . Biol Pharm Bull (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology CLSPN antibody (Cell Signaling Technology, 2800) was used in western blot on human samples (fig 5). FEBS Lett (2013) ncbi
Articles Reviewed
  1. Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed publisher
  2. Twardziok M, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, et al. Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma. PLoS ONE. 2016;11:e0159749 pubmed publisher
  3. Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed
  4. Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
  5. Zhu M, Zhao H, Liao J, Xu X. HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability. Nucleic Acids Res. 2014;42:13074-81 pubmed publisher
  6. Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  7. Adeyemi R, Pintel D. The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice. J Virol. 2014;88:10189-99 pubmed publisher
  8. Matsumoto T, Tabata K, Suzuki T. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells. Biol Pharm Bull. 2014;37:633-41 pubmed
  9. Ding G, Liu H, Liang H, Ni R, Ding Z, Ni G, et al. HIF1-regulated ATRIP expression is required for hypoxia induced ATR activation. FEBS Lett. 2013;587:930-5 pubmed publisher