This is a Validated Antibody Database (VAD) review about human CLOCK, based on 7 published articles (read how Labome selects the articles), using CLOCK antibody in all methods. It is aimed to help Labome visitors find the most suited CLOCK antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CLOCK synonym: KAT13D; bHLHe8

Santa Cruz Biotechnology
mouse monoclonal (C-8)
  • western blot; human; 1:200; loading ...; fig 1c
  • immunohistochemistry; rat; 1:100; loading ...; fig 2e
Santa Cruz Biotechnology CLOCK antibody (SantaCruz, sc-271603) was used in western blot on human samples at 1:200 (fig 1c) and in immunohistochemistry on rat samples at 1:100 (fig 2e). PLoS ONE (2018) ncbi
mouse monoclonal (C-8)
  • immunoprecipitation; mouse; fig 5
  • western blot; mouse; 1:200; fig 2e
Santa Cruz Biotechnology CLOCK antibody (Santa Cruz Biotechnology, sc-271603) was used in immunoprecipitation on mouse samples (fig 5) and in western blot on mouse samples at 1:200 (fig 2e). Exp Biol Med (Maywood) (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2a
Invitrogen CLOCK antibody (Affinity BioReagents, PA1-520) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 2a). J Pineal Res (2019) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:500; loading ...; fig 2e
  • western blot; human; 1:500; loading ...; fig 2c
Abcam CLOCK antibody (Abcam, ab3517) was used in immunohistochemistry on human samples at 1:500 (fig 2e) and in western blot on human samples at 1:500 (fig 2c). Neuron (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D45B10)
  • western blot; mouse; loading ...; fig 2c
Cell Signaling Technology CLOCK antibody (Cell Signaling, 5157) was used in western blot on mouse samples (fig 2c). Mol Neurobiol (2018) ncbi
domestic rabbit monoclonal (D45B10)
  • western blot; rat; loading ...; fig 5a
Cell Signaling Technology CLOCK antibody (Cell Signaling, 5157) was used in western blot on rat samples (fig 5a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D45B10)
  • western blot; mouse; 1:1000
In order to study actin dynamics during podosome patterning, Cell Signaling Technology CLOCK antibody (Cell Signaling, 5157) was used in western blot on mouse samples at 1:1000. Mol Biol Cell (2014) ncbi
Articles Reviewed
  1. Jilg A, Bechstein P, Saade A, Dick M, Li T, Tosini G, et al. Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res. 2019;66:e12553 pubmed publisher
  2. Kim H, Kim H, Kim J, Kim T, Lee S. Asymmetric expression level of clock genes in left vs. right nasal mucosa in humans with and without allergies and in rats: Circadian characteristics and possible contribution to nasal cycle. PLoS ONE. 2018;13:e0194018 pubmed publisher
  3. Li P, Fu X, Smith N, Ziobro J, Curiel J, Tenga M, et al. Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy. Neuron. 2017;96:387-401.e6 pubmed publisher
  4. Beker M, Çağlayan B, Yalcin E, Caglayan A, Turkseven S, Gurel B, et al. Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT. Mol Neurobiol. 2018;55:2565-2576 pubmed publisher
  5. Suyama K, Silagi E, Choi H, Sakabe K, Mochida J, Shapiro I, et al. Circadian factors BMAL1 and ROR? control HIF-1? transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016;7:23056-71 pubmed publisher
  6. Cheng S, Liang X, Wang Y, Jiang Z, Liu Y, Hou W, et al. The circadian Clock gene regulates acrosin activity of sperm through serine protease inhibitor A3K. Exp Biol Med (Maywood). 2016;241:205-15 pubmed publisher
  7. Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed publisher