This is a Validated Antibody Database (VAD) review about human CLEC7A, based on 9 published articles (read how Labome selects the articles), using CLEC7A antibody in all methods. It is aimed to help Labome visitors find the most suited CLEC7A antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CLEC7A synonym: BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2; C-type lectin domain family 7 member A; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin superfamily member 12; DC-associated C-type lectin 1; beta-glucan receptor; dectin-1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1

Knockout validation
Abcam
rat monoclonal (2A11)
  • immunohistochemistry knockout validation; mouse; 20 ug/ml; loading ...; fig s1a
  • immunohistochemistry - frozen section; mouse; 20 ug/ml; loading ...; fig s1a
  • flow cytometry; mouse; loading ...; fig 1b
Abcam CLEC7A antibody (Abcam, 2A11) was used in immunohistochemistry knockout validation on mouse samples at 20 ug/ml (fig s1a), in immunohistochemistry - frozen section on mouse samples at 20 ug/ml (fig s1a) and in flow cytometry on mouse samples (fig 1b). Nat Med (2017) ncbi
R&D Systems
mouse monoclonal (259931)
  • flow cytometry; human
In order to evaluate combinations of TLR and C-type lectin receptor agonists on the Th1 responses of newborn dendritic cells, R&D Systems CLEC7A antibody (R&D Systems, 259931) was used in flow cytometry on human samples . J Immunol (2016) ncbi
mouse monoclonal (259931)
  • flow cytometry; human; loading ...
R&D Systems CLEC7A antibody (R&D Systems, FAB1859P) was used in flow cytometry on human samples . Clin Transl Immunology (2016) ncbi
mouse monoclonal (259931)
  • immunohistochemistry - paraffin section; human; 10 ug/ml
  • immunocytochemistry; human
R&D Systems CLEC7A antibody (R&D Systems, MAB1859) was used in immunohistochemistry - paraffin section on human samples at 10 ug/ml and in immunocytochemistry on human samples . Eur J Immunol (2014) ncbi
mouse monoclonal (259931)
  • immunohistochemistry - paraffin section; human; 1:50
R&D Systems CLEC7A antibody (R&D Systems, MAB 1859) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Invest Dermatol (2010) ncbi
Abcam
rat monoclonal (2A11)
  • immunohistochemistry knockout validation; mouse; 20 ug/ml; loading ...; fig s1a
  • immunohistochemistry - frozen section; mouse; 20 ug/ml; loading ...; fig s1a
  • flow cytometry; mouse; loading ...; fig 1b
Abcam CLEC7A antibody (Abcam, 2A11) was used in immunohistochemistry knockout validation on mouse samples at 20 ug/ml (fig s1a), in immunohistochemistry - frozen section on mouse samples at 20 ug/ml (fig s1a) and in flow cytometry on mouse samples (fig 1b). Nat Med (2017) ncbi
mouse monoclonal (GE2)
  • western blot; mouse; loading ...; fig 2a
Abcam CLEC7A antibody (Abcam, Ab82888) was used in western blot on mouse samples (fig 2a). Nat Med (2016) ncbi
Miltenyi Biotec
human monoclonal (REA515)
  • flow cytometry; human; tbl 1
In order to compare methods of isolating skin mononuclear phagocytes, Miltenyi Biotec CLEC7A antibody (Miltenyi Biotech, REA515) was used in flow cytometry on human samples (tbl 1). J Leukoc Biol (2017) ncbi
Invitrogen
mouse monoclonal (15E2)
  • flow cytometry; human; loading ...; fig 1d
In order to elucidate the role of pattern recognition receptors in Bechet's disease, Invitrogen CLEC7A antibody (eBioscience, 1-46-9856-42) was used in flow cytometry on human samples (fig 1d). Mediators Inflamm (2017) ncbi
Bio-Rad
mouse monoclonal (GE2)
  • flow cytometry; human
Bio-Rad CLEC7A antibody (AbD Serotec, MCA4661F) was used in flow cytometry on human samples . Eur J Immunol (2014) ncbi
mouse monoclonal (BD6)
  • immunocytochemistry; human; fig 6
Bio-Rad CLEC7A antibody (AbD Serotec, BD6) was used in immunocytochemistry on human samples (fig 6). Nat Immunol (2014) ncbi
Articles Reviewed
  1. Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
  2. Choi B, Suh C, Kim H, Sayeed H, Sohn S. The Correlation of CD206, CD209, and Disease Severity in Behçet's Disease with Arthritis. Mediators Inflamm. 2017;2017:7539529 pubmed publisher
  3. Botting R, Bertram K, Baharlou H, Sandgren K, Fletcher J, Rhodes J, et al. Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. J Leukoc Biol. 2017;101:1393-1403 pubmed publisher
  4. van Haren S, Dowling D, Foppen W, Christensen D, Andersen P, Reed S, et al. Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization. J Immunol. 2016;197:4413-4424 pubmed
  5. Xiao Y, Tang J, Guo H, Zhao Y, Tang R, Ouyang S, et al. Targeting CBLB as a potential therapeutic approach for disseminated candidiasis. Nat Med. 2016;22:906-14 pubmed publisher
  6. Ohradanova Repic A, Machacek C, Fischer M, Stockinger H. Differentiation of human monocytes and derived subsets of macrophages and dendritic cells by the HLDA10 monoclonal antibody panel. Clin Transl Immunology. 2016;5:e55 pubmed publisher
  7. Cohen Kedar S, Baram L, Elad H, Brazowski E, Guzner Gur H, Dotan I. Human intestinal epithelial cells respond to β-glucans via Dectin-1 and Syk. Eur J Immunol. 2014;44:3729-40 pubmed publisher
  8. Branzk N, Lubojemska A, Hardison S, Wang Q, Gutierrez M, Brown G, et al. Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens. Nat Immunol. 2014;15:1017-25 pubmed publisher
  9. de Koning H, Rodijk Olthuis D, van Vlijmen Willems I, Joosten L, Netea M, Schalkwijk J, et al. A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis. J Invest Dermatol. 2010;130:2611-20 pubmed publisher