This is a Validated Antibody Database (VAD) review about human CLEC4C, based on 11 published articles (read how Labome selects the articles), using CLEC4C antibody in all methods. It is aimed to help Labome visitors find the most suited CLEC4C antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CLEC4C synonym: BDCA2; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; C-type lectin domain family 4 member C; BDCA-2; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 7; C-type lectin domain family 4, member C; C-type lectin superfamily member 7; blood dendritic cell antigen 2 protein; dendritic cell lectin b; dendritic lectin

BioLegend
mouse monoclonal (201A)
  • flow cytometry; human; loading ...; fig 4a
BioLegend CLEC4C antibody (BioLegend, 201A) was used in flow cytometry on human samples (fig 4a). J Clin Invest (2018) ncbi
mouse monoclonal (201A)
  • mass cytometry; human; loading ...; fig s3b
In order to map the lineage of human dendritic cells, BioLegend CLEC4C antibody (BioLegend, 201A) was used in mass cytometry on human samples (fig s3b). Science (2017) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, BioLegend CLEC4C antibody (Biolegend, 201A) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; loading ...; fig 5b
In order to study the effect of LL37 peptide in the immune over-activation of Behcet's disease., BioLegend CLEC4C antibody (Biolegend, 354208) was used in flow cytometry on human samples (fig 5b). J Extracell Vesicles (2017) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; 1:100; fig 1
BioLegend CLEC4C antibody (Biolegend, 201A) was used in flow cytometry on human samples at 1:100 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; 1:100
In order to develop a system to determine human DC development and differentiation, BioLegend CLEC4C antibody (Biolegend, 201A) was used in flow cytometry on human samples at 1:100. J Immunol Methods (2015) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; fig 1
In order to study human cord blood and bone marrow for restricted dendritic cell and monocyte progenitors, BioLegend CLEC4C antibody (Biolegend, 201A) was used in flow cytometry on human samples (fig 1). J Exp Med (2015) ncbi
Invitrogen
mouse monoclonal (201A)
  • flow cytometry; human; loading ...; fig 1a, 1b
In order to discuss targeting CD123 to treat systemic lupus erythematosus, Invitrogen CLEC4C antibody (E-Bioscience, 25-9818-42) was used in flow cytometry on human samples (fig 1a, 1b). JCI Insight (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; fig 4
In order to assess the contribution of type I and II IFN to different Sjogren's syndrome subsets, Invitrogen CLEC4C antibody (Thermo Scientific, OSD00005W) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 4). J Autoimmun (2015) ncbi
mouse monoclonal (201A)
  • flow cytometry; human
Invitrogen CLEC4C antibody (eBioscience Inc., 201A) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (201A)
  • flow cytometry; human; fig s5
Invitrogen CLEC4C antibody (Ebioscience, 11-9818-42) was used in flow cytometry on human samples (fig s5). PLoS Pathog (2014) ncbi
Articles Reviewed
  1. Boutboul D, Kuehn H, Van de Wyngaert Z, Niemela J, Callebaut I, Stoddard J, et al. Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. J Clin Invest. 2018;128:3071-3087 pubmed publisher
  2. See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  3. Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
  4. Kahraman T, Gucluler G, Simsek I, Yagci F, Yildirim M, Ozen C, et al. Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet's disease severity. J Extracell Vesicles. 2017;6:1284449 pubmed publisher
  5. Oon S, Huynh H, Tai T, Ng M, Monaghan K, Biondo M, et al. A cytotoxic anti-IL-3R? antibody targets key cells and cytokines implicated in systemic lupus erythematosus. JCI Insight. 2016;1:e86131 pubmed
  6. Leone D, Kozakowski N, Kornauth C, Waidacher T, Neudert B, Loeffler A, et al. The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury. PLoS ONE. 2016;11:e0151674 pubmed publisher
  7. Nezos A, Gravani F, Tassidou A, Kapsogeorgou E, Voulgarelis M, Koutsilieris M, et al. Type I and II interferon signatures in Sjogren's syndrome pathogenesis: Contributions in distinct clinical phenotypes and Sjogren's related lymphomagenesis. J Autoimmun. 2015;63:47-58 pubmed publisher
  8. Lee J, Breton G, Aljoufi A, Zhou Y, PUHR S, Nussenzweig M, et al. Clonal analysis of human dendritic cell progenitor using a stromal cell culture. J Immunol Methods. 2015;425:21-6 pubmed publisher
  9. Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  10. Skrnjug I, Rueckert C, Libanova R, Lienenklaus S, Weiss S, Guzman C. The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages. PLoS ONE. 2014;9:e95728 pubmed publisher
  11. Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, et al. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection. PLoS Pathog. 2014;10:e1003885 pubmed publisher