This is a Validated Antibody Database (VAD) review about human CIITA, based on 5 published articles (read how Labome selects the articles), using CIITA antibody in all methods. It is aimed to help Labome visitors find the most suited CIITA antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CIITA synonym: C2TA; CIITAIV; MHC2TA; NLRA

Santa Cruz Biotechnology
mouse monoclonal (7-1H)
  • western blot; human; fig 2d
Santa Cruz Biotechnology CIITA antibody (Santa Cruz, sc-13556) was used in western blot on human samples (fig 2d). Oncoimmunology (2022) ncbi
mouse monoclonal (7-1H)
  • western blot; human; 1:1000; loading ...; fig 1
Santa Cruz Biotechnology CIITA antibody (Santa Cruz, 7-1H) was used in western blot on human samples at 1:1000 (fig 1). Front Immunol (2017) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 1
Santa Cruz Biotechnology CIITA antibody (Santa Cruz, 7-1H) was used in western blot on human samples at 1:1000 (fig 1). Front Immunol (2017) ncbi
mouse monoclonal (7-1H)
  • immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology CIITA antibody (SantaCruz, 7-1H) was used in immunoprecipitation on human samples (fig 2c) and in western blot on human samples (fig 2c). J Transl Med (2016) ncbi
mouse monoclonal
  • immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology CIITA antibody (SantaCruz, 7-1H) was used in immunoprecipitation on human samples (fig 2c) and in western blot on human samples (fig 2c). J Transl Med (2016) ncbi
Rockland Immunochemicals
domestic rabbit polyclonal
  • ChIP-Seq; human; fig 4a
  • chromatin immunoprecipitation; human; fig 4c
Rockland Immunochemicals CIITA antibody (Rockland Immunochemicals Inc, 100-401-249) was used in ChIP-Seq on human samples (fig 4a) and in chromatin immunoprecipitation on human samples (fig 4c). PLoS Pathog (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology CIITA antibody (Cell Signaling Technology, 3793) was used in western blot on human samples at 1:1000 (fig 2). Nat Commun (2016) ncbi
Articles Reviewed
  1. Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, et al. Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma. Oncoimmunology. 2022;11:2021619 pubmed publisher
  2. Su C, Lu F, Soldan S, Lamontagne R, Tang H, Napoletani G, et al. EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes. PLoS Pathog. 2021;17:e1009834 pubmed publisher
  3. Forlani G, Tosi G, Turrini F, Poli G, Vicenzi E, Accolla R. Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1. Front Immunol. 2017;8:564 pubmed publisher
  4. Forlani G, Turrini F, Ghezzi S, Tedeschi A, Poli G, Accolla R, et al. The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells. J Transl Med. 2016;14:94 pubmed publisher
  5. Johnson D, Estrada M, Salgado R, Sanchez V, Doxie D, Opalenik S, et al. Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy. Nat Commun. 2016;7:10582 pubmed publisher