This is a Validated Antibody Database (VAD) review about human CHMP2B, based on 4 published articles (read how Labome selects the articles), using CHMP2B antibody in all methods. It is aimed to help Labome visitors find the most suited CHMP2B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CHMP2B synonym: ALS17; CHMP2.5; DMT1; VPS2-2; VPS2B

Abcam
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 1a
Abcam CHMP2B antibody (Abcam, ab33174) was used in immunocytochemistry on human samples (fig 1a). Science (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Abcam CHMP2B antibody (Abcam, AB33174) was used in western blot on human samples at 1:1000 (fig 2). Hum Mol Genet (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:600; fig 3
In order to study the relationship between neurofibrillary tangles and raft domains, Abcam CHMP2B antibody (Abcam, ab33174) was used in immunohistochemistry - paraffin section on human samples at 1:600 (fig 3). Neuropathol Appl Neurobiol (2016) ncbi
R&D Systems
domestic sheep polyclonal
  • immunocytochemistry; rat; loading ...; fig 4d
R&D Systems CHMP2B antibody (R&D System, AF7509) was used in immunocytochemistry on rat samples (fig 4d). Front Cell Dev Biol (2020) ncbi
Articles Reviewed
  1. Li T, Yin Y, Mu N, Wang Y, Liu M, Chen M, et al. Metformin-Enhanced Cardiac AMP-Activated Protein Kinase/Atrogin-1 Pathways Inhibit Charged Multivesicular Body Protein 2B Accumulation in Ischemia-Reperfusion Injury. Front Cell Dev Biol. 2020;8:621509 pubmed publisher
  2. Skowyra M, Schlesinger P, Naismith T, Hanson P. Triggered recruitment of ESCRT machinery promotes endolysosomal repair. Science. 2018;360: pubmed publisher
  3. Vernay A, Therreau L, Blot B, Risson V, Dirrig Grosch S, Waegaert R, et al. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia. Hum Mol Genet. 2016;25:3341-3360 pubmed publisher
  4. Nishikawa T, Takahashi T, Nakamori M, Hosomi N, Maruyama H, Miyazaki Y, et al. The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments. Neuropathol Appl Neurobiol. 2016;42:639-653 pubmed publisher