This is a Validated Antibody Database (VAD) review about human CEP170, based on 6 published articles (read how Labome selects the articles), using CEP170 antibody in all methods. It is aimed to help Labome visitors find the most suited CEP170 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CEP170 synonym: FAM68A; KAB; KIAA0470; centrosomal protein of 170 kDa; KARP-1-binding protein; XRCC5 binding protein; centrosomal protein 170kDa

Invitrogen
mouse monoclonal (72-413-1)
  • immunocytochemistry; human; fig 2a
In order to study the association of IFT-B with CEP19-RABL2 GTPase complex and it role in intraflagellar transport, Invitrogen CEP170 antibody (Thermo Fisher, 41-3200) was used in immunocytochemistry on human samples (fig 2a). Dev Cell (2017) ncbi
mouse monoclonal (72-413-1)
  • immunocytochemistry; human; 1:50; fig 1
In order to analyze prevention of centrosome amplification and neoplastic progression by 14-3-3gamma, Invitrogen CEP170 antibody (Invitrogen, 41-3200) was used in immunocytochemistry on human samples at 1:50 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (72-413-1)
  • immunocytochemistry; human; 1:500; fig s2
In order to learn regulation of actin network architecture and ciliogenesis due to STAR syndrome-associated CDK10/Cyclin M, Invitrogen CEP170 antibody (Life Technologies, 41-3200) was used in immunocytochemistry on human samples at 1:500 (fig s2). Cell Cycle (2016) ncbi
mouse monoclonal (72-413-1)
  • immunoprecipitation; human; fig 5
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:1000; fig 5
In order to determine how Tank binding kinase 1 works in mitosis and microtubule dynamiccs, Invitrogen CEP170 antibody (Invitrogen, 41-3200) was used in immunoprecipitation on human samples (fig 5), in immunocytochemistry on human samples at 1:100 (fig 4) and in western blot on human samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (72-413-1)
  • western blot; human; fig 1
In order to characterize the role of BAG3-HSPB8 in mitosis, Invitrogen CEP170 antibody (Invitrogen, 413200) was used in western blot on human samples (fig 1). PLoS Genet (2015) ncbi
mouse monoclonal (72-413-1)
  • immunocytochemistry; human; 1:500
In order to examine centriole behavior after DNA damage in synchronized untransformed human cells, Invitrogen CEP170 antibody (Invitrogen, 41-3200) was used in immunocytochemistry on human samples at 1:500. J Cell Physiol (2014) ncbi
Articles Reviewed
  1. Kanie T, Abbott K, Mooney N, Plowey E, Demeter J, JACKSON P. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017;42:22-36.e12 pubmed publisher
  2. Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, et al. 14-3-3? Prevents Centrosome Amplification and Neoplastic Progression. Sci Rep. 2016;6:26580 pubmed publisher
  3. Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  4. Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed publisher
  5. Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
  6. Douthwright S, Sluder G. Link between DNA damage and centriole disengagement/reduplication in untransformed human cells. J Cell Physiol. 2014;229:1427-36 pubmed publisher