This is a Validated Antibody Database (VAD) review about human CDT1, based on 12 published articles (read how Labome selects the articles), using CDT1 antibody in all methods. It is aimed to help Labome visitors find the most suited CDT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDT1 synonym: DUP; RIS2

Abcam
domestic rabbit monoclonal (EPR17891)
  • flow cytometry; human; 1:100; loading ...; fig 4s1b
Abcam CDT1 antibody (Abcam, ab202067) was used in flow cytometry on human samples at 1:100 (fig 4s1b). elife (2017) ncbi
domestic rabbit monoclonal (EPR17891)
  • flow cytometry; human; 1:100; loading ...
In order to determine specific residues on four MCM helicase subunits that show hyperphosphorylation upon RIF1 depletion, Abcam CDT1 antibody (Abcam, ab202067) was used in flow cytometry on human samples at 1:100. EMBO Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
Abcam CDT1 antibody (Abcam, ab183478) was used in western blot on human samples (fig s2). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; fig 1
Abcam CDT1 antibody (Abcam, ab70829) was used in western blot on human samples at 1:2000 (fig 1). Mol Cell Biol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-6)
  • western blot; mouse; loading ...; fig 5g
Santa Cruz Biotechnology CDT1 antibody (Santa Cruz Biotechnology, sc-365305) was used in western blot on mouse samples (fig 5g). Development (2019) ncbi
mouse monoclonal (F-6)
  • western blot; human; loading ...; fig 6a
Santa Cruz Biotechnology CDT1 antibody (Santa, sc-365305) was used in western blot on human samples (fig 6a). Nat Chem Biol (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D10F11)
  • western blot; human; 1:10,000; loading ...; fig 3s1a
Cell Signaling Technology CDT1 antibody (Cell Signaling Technologies, 8064S) was used in western blot on human samples at 1:10,000 (fig 3s1a). elife (2017) ncbi
domestic rabbit monoclonal (D10F11)
  • western blot; human; loading ...; fig s2a
In order to research the association between phosphorylated SIRT1 with replication origins and its effect on genomic stability, Cell Signaling Technology CDT1 antibody (Cell Signaling, 8064) was used in western blot on human samples (fig s2a). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (D10F11)
  • western blot; human; fig 6a
In order to assess the effects of the PCNA S228I mutation that causes proliferating cell nuclear antigen-associated DNA repair disorder, Cell Signaling Technology CDT1 antibody (Cell Signalling Technology, D10F11) was used in western blot on human samples (fig 6a). DNA Repair (Amst) (2017) ncbi
domestic rabbit monoclonal (D10F11)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology CDT1 antibody (Cell Signaling, 8064) was used in western blot on human samples (fig 1a). Oncogene (2016) ncbi
domestic rabbit monoclonal (D10F11)
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology CDT1 antibody (Cell Signaling, 8064) was used in western blot on human samples at 1:1000 (fig 1). Nat Commun (2014) ncbi
domestic rabbit monoclonal (D10F11)
  • western blot; human
Cell Signaling Technology CDT1 antibody (Cell Signaling, #8064) was used in western blot on human samples . J Biol Chem (2014) ncbi
EMD Millipore
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
EMD Millipore CDT1 antibody (Millipore, 07-1383) was used in western blot on mouse samples at 1:1000 (fig 5). Mol Biol Cell (2016) ncbi
Articles Reviewed
  1. Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, et al. Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019;146: pubmed publisher
  2. Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  3. Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
  4. Utani K, Fu H, Jang S, Marks A, Smith O, Zhang Y, et al. Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability. Nucleic Acids Res. 2017;45:7807-7824 pubmed publisher
  5. Hiraga S, Ly T, Garzón J, Horejsi Z, Ohkubo Y, Endo A, et al. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep. 2017;18:403-419 pubmed publisher
  6. Wilson R, Biasutto A, Wang L, Fischer R, Baple E, Crosby A, et al. PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst). 2017;50:22-35 pubmed publisher
  7. Moreno A, Carrington J, Albergante L, Al Mamun M, Haagensen E, Komseli E, et al. Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells. Proc Natl Acad Sci U S A. 2016;113:E5757-64 pubmed publisher
  8. Ma X, Lin F, Wang Z, Hu M, Huang L, Meng T, et al. Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility. Mol Biol Cell. 2016;27:768-75 pubmed publisher
  9. Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al. Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation. Mol Cell Biol. 2016;36:615-27 pubmed publisher
  10. Greil C, Krohs J, Schnerch D, Follo M, Felthaus J, Engelhardt M, et al. The role of APC/C(Cdh1) in replication stress and origin of genomic instability. Oncogene. 2016;35:3062-70 pubmed publisher
  11. Fernandez Vidal A, Guitton Sert L, Cadoret J, Drac M, Schwob E, Baldacci G, et al. A role for DNA polymerase ? in the timing of DNA replication. Nat Commun. 2014;5:4285 pubmed publisher
  12. Johansson P, Jeffery J, Al Ejeh F, Schulz R, Callen D, Kumar R, et al. SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication. J Biol Chem. 2014;289:18514-25 pubmed publisher