This is a Validated Antibody Database (VAD) review about human CDK5RAP2, based on 8 published articles (read how Labome selects the articles), using CDK5RAP2 antibody in all methods. It is aimed to help Labome visitors find the most suited CDK5RAP2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDK5RAP2 synonym: C48; Cep215; MCPH3; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; centrosomal protein 215 kDa; centrosomin

Bethyl
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 2h
In order to investigate the conversion of mitochondria to microtubule-organizing centers through a centrosomin splice variant, Bethyl CDK5RAP2 antibody (Bethyl Laboratories, A300-554A) was used in immunocytochemistry on human samples (fig 2h). Curr Biol (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig s8c
In order to reveal critical and diverse functions of WD repeat domain 62 in neocortical development, Bethyl CDK5RAP2 antibody (Bethyl, IHC-00063) was used in immunohistochemistry on mouse samples at 1:100 (fig s8c). Sci Rep (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 3
  • western blot; human; 1:500; fig 2
Bethyl CDK5RAP2 antibody (Bethyl laboratories, A300-C554A) was used in immunocytochemistry on human samples at 1:500 (fig 3) and in western blot on human samples at 1:500 (fig 2). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 3
Bethyl CDK5RAP2 antibody (Bethyl Laboratories, IHC-00063) was used in immunocytochemistry on human samples at 1:500 (fig 3). J Cell Biol (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 6
  • western blot; human; 1:1000; fig 1
In order to report how Cep68 regulates centriole disengagement, Bethyl CDK5RAP2 antibody (Bethyl, A300-554A) was used in immunocytochemistry on human samples (fig 6) and in western blot on human samples at 1:1000 (fig 1). Nat Cell Biol (2015) ncbi
EMD Millipore
rabbit polyclonal
  • western blot; mouse; fig 2
In order to study functionally distinct gamma-tubulin complexes and divergent regulation during differentiation, EMD Millipore CDK5RAP2 antibody (Millipore, 06-1398) was used in western blot on mouse samples (fig 2). J Cell Biol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:2000; fig s4
  • western blot; human; 1:2000; fig s4
EMD Millipore CDK5RAP2 antibody (Millipore, 06-1398) was used in immunocytochemistry on human samples at 1:2000 (fig s4) and in western blot on human samples at 1:2000 (fig s4). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:1000; loading ...; fig 2d
EMD Millipore CDK5RAP2 antibody (Millipore, 06-1398) was used in immunocytochemistry on human samples at 1:1000 (fig 2d). Mol Biol Cell (2015) ncbi
Articles Reviewed
  1. Chen J, Buchwalter R, Kao L, Megraw T. A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers. Curr Biol. 2017;27:1928-1940.e6 pubmed publisher
  2. Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
  3. Muroyama A, Seldin L, Lechler T. Divergent regulation of functionally distinct γ-tubulin complexes during differentiation. J Cell Biol. 2016;213:679-92 pubmed publisher
  4. Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed publisher
  5. Shukla A, Kong D, Sharma M, Magidson V, Loncarek J. Plk1 relieves centriole block to reduplication by promoting daughter centriole maturation. Nat Commun. 2015;6:8077 pubmed publisher
  6. Prosser S, Sahota N, Pelletier L, Morrison C, Fry A. Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J Cell Biol. 2015;209:339-48 pubmed publisher
  7. Ohta S, Wood L, Toramoto I, Yagyu K, Fukagawa T, Earnshaw W. CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly. Mol Biol Cell. 2015;26:1225-37 pubmed publisher
  8. Pagan J, Marzio A, Jones M, Saraf A, Jallepalli P, Florens L, et al. Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing. Nat Cell Biol. 2015;17:31-43 pubmed publisher