This is a Validated Antibody Database (VAD) review about human CDK12, based on 4 published articles (read how Labome selects the articles), using CDK12 antibody in all methods. It is aimed to help Labome visitors find the most suited CDK12 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDK12 synonym: CRK7; CRKR; CRKRS; cyclin-dependent kinase 12; CDC2-related protein kinase 7; Cdc2-related kinase, arginine/serine-rich; cell division cycle 2-related protein kinase 7; cell division protein kinase 12

Santa Cruz Biotechnology
mouse monoclonal (R-12)
  • western blot; human; fig 4
Santa Cruz Biotechnology CDK12 antibody (Santa Cruz, sc-81834) was used in western blot on human samples (fig 4). PLoS ONE (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; fig 1c
Cell Signaling Technology CDK12 antibody (Cell Signaling, 11973) was used in western blot on human samples (fig 1c). Cell Res (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology CDK12 antibody (Cell Signaling, 11973) was used in western blot on human samples (fig 2a). Tumour Biol (2017) ncbi
rabbit polyclonal
  • western blot; human
In order to study the effects of cyclin-dependent kinase 7 inhibitors on MYC proteins, Cell Signaling Technology CDK12 antibody (Cell Signaling, 11973) was used in western blot on human samples . Cell (2014) ncbi
Articles Reviewed
  1. Yu F, Shi G, Cheng S, Chen J, Wu S, Wang Z, et al. SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Res. 2018;28:670-685 pubmed publisher
  2. Paculova H, Kramara J, Simečková S, Fedr R, Soucek K, Hylse O, et al. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumour Biol. 2017;39:1010428317727479 pubmed publisher
  3. Albert T, Antrecht C, Kremmer E, Meisterernst M. The Establishment of a Hyperactive Structure Allows the Tumour Suppressor Protein p53 to Function through P-TEFb during Limited CDK9 Kinase Inhibition. PLoS ONE. 2016;11:e0146648 pubmed publisher
  4. Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-1139 pubmed publisher