This is a Validated Antibody Database (VAD) review about human CDH6, based on 9 published articles (read how Labome selects the articles), using CDH6 antibody in all methods. It is aimed to help Labome visitors find the most suited CDH6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDH6 synonym: CAD6; KCAD; cadherin-6; cadherin 6, type 2, K-cadherin (fetal kidney)

Abcam
mouse monoclonal (mAbcam22744)
  • western blot; mouse; 1:10,000; loading ...; fig s2b
  • western blot; human; 1:10,000; loading ...; fig 1c
Abcam CDH6 antibody (Abcam, AB22744) was used in western blot on mouse samples at 1:10,000 (fig s2b) and in western blot on human samples at 1:10,000 (fig 1c). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (mAbcam22744)
  • immunocytochemistry; human; loading ...; fig s5d
In order to research the role of manganese efflux transporters in the maintenance of manganese homeostasis, Abcam CDH6 antibody (Abcam, ab22744) was used in immunocytochemistry on human samples (fig s5d). PLoS Genet (2017) ncbi
mouse monoclonal (mAbcam22744)
  • western blot; rat; loading ...; fig 3b
In order to ask if SK channels in the mitochondria inner membrane play an important role in regulating mitochondrial function in chronic cardiac diseases, Abcam CDH6 antibody (Abcam, ab22744) was used in western blot on rat samples (fig 3b). Cardiovasc Res (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 3b
  • western blot; mouse; 1:500; fig 1b
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 3d
  • western blot; human; 1:500; loading ...; fig 4b
In order to find that CDH6 is expressed in the oviduct and is repressed by mutant p53, Abcam CDH6 antibody (Abcam, ab197845) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 3b), in western blot on mouse samples at 1:500 (fig 1b), in immunohistochemistry - paraffin section on human samples at 1:50 (fig 3d) and in western blot on human samples at 1:500 (fig 4b). Oncotarget (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (CH-19)
  • western blot; mouse; loading ...; fig 4a
Santa Cruz Biotechnology CDH6 antibody (Santa Cruz, sc-59876) was used in western blot on mouse samples (fig 4a). J Clin Invest (2017) ncbi
mouse monoclonal (CH-19)
  • western blot; mouse; 1:4000; loading ...; fig 5c
Santa Cruz Biotechnology CDH6 antibody (Santa Cruz Biotechnology, sc-59876) was used in western blot on mouse samples at 1:4000 (fig 5c). Nat Neurosci (2014) ncbi
R&D Systems
mouse monoclonal (427909)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, R&D Systems CDH6 antibody (R&D Systems, FAB2715A) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
Invitrogen
mouse monoclonal (2B6)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3a
In order to identify epigenetically altered miRNAs in patients with cholangiocarcinogenesis, Invitrogen CDH6 antibody (Thermo Fischer, MA1-06305) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3a). Epigenetics (2016) ncbi
MilliporeSigma
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 3
In order to describe a protocol for pluripotent-stem-cell-based renal regeneration, MilliporeSigma CDH6 antibody (Sigma Aldrich, HPA007047) was used in immunocytochemistry on human samples at 1:100 (fig 3). Nat Cell Biol (2014) ncbi
Articles Reviewed
  1. Seo B, Cho T, Lee D, Lee J, Lee B, Kim S, et al. LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory. Proc Natl Acad Sci U S A. 2018;115:7111-7116 pubmed publisher
  2. Rong X, Wang B, Palladino E, de Aguiar Vallim T, Ford D, Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest. 2017;127:3640-3651 pubmed publisher
  3. Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, et al. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genet. 2017;13:e1006892 pubmed publisher
  4. Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  5. Goeppert B, Ernst C, Baer C, Roessler S, Renner M, Mehrabi A, et al. Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma. Epigenetics. 2016;11:780-790 pubmed
  6. Karthikeyan S, Lantvit D, Chae D, Burdette J. Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Oncotarget. 2016;7:69871-69882 pubmed publisher
  7. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  8. Lee Y, Ehninger D, Zhou M, Oh J, Kang M, Kwak C, et al. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2014;17:1736-43 pubmed publisher
  9. Takasato M, Er P, Becroft M, Vanslambrouck J, Stanley E, Elefanty A, et al. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat Cell Biol. 2014;16:118-26 pubmed publisher