This is a Validated Antibody Database (VAD) review about human CDC6, based on 23 published articles (read how Labome selects the articles), using CDC6 antibody in all methods. It is aimed to help Labome visitors find the most suited CDC6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CDC6 synonym: CDC18L; HsCDC18; HsCDC6; MGORS5

Santa Cruz Biotechnology
mouse monoclonal (180.2)
  • western blot; human; 1:500; loading ...; fig 4b
Santa Cruz Biotechnology CDC6 antibody (SantaCruz, sc-9964) was used in western blot on human samples at 1:500 (fig 4b). Nat Commun (2018) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:20,000; loading ...; fig s2e
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz Biotechnology, sc-9964) was used in western blot on human samples at 1:20,000 (fig s2e). elife (2017) ncbi
mouse monoclonal (D-1)
  • western blot; mouse; 1:200; loading ...; fig s2c
In order to investigate the contribution of Huwe1 in proliferating stem cells of the adult mouse hippocampus to the return to quiescence, Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, sc-13136) was used in western blot on mouse samples at 1:200 (fig s2c). Science (2016) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:1500; fig 1
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, sc-9964) was used in western blot on human samples at 1:1500 (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:1000; fig s7
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz Biotechnology, sc-9964) was used in western blot on human samples at 1:1000 (fig s7). Nat Commun (2016) ncbi
mouse monoclonal (180.2)
  • western blot; human; loading ...; fig 1b
In order to study quinacrine-induced apoptosis, Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, sc9964) was used in western blot on human samples (fig 1b). Biochem Pharmacol (2016) ncbi
mouse monoclonal (D-1)
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology CDC6 antibody (santa, sc-13136) was used in western blot on human samples (fig 1a). Oncogene (2016) ncbi
mouse monoclonal (180.2)
  • western blot; human; fig 8
In order to determine how cytosolic phospholipase A2alpha prohibits prostate cancer cells from re-entering the cell cyle, Santa Cruz Biotechnology CDC6 antibody (Santa Cruz Biotechnology, sc-9964) was used in western blot on human samples (fig 8). Oncotarget (2015) ncbi
mouse monoclonal (180.2)
  • western blot; mouse; 1:200; fig 2
Santa Cruz Biotechnology CDC6 antibody (santa Cruz, sc-9964) was used in western blot on mouse samples at 1:200 (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal (180.2)
  • western blot; human; fig 2a
Santa Cruz Biotechnology CDC6 antibody (Santa, 180.2) was used in western blot on human samples (fig 2a). J Biol Chem (2014) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz Biotechnology, sc-9964) was used in western blot on human samples at 1:500 (fig 1). Nat Commun (2014) ncbi
mouse monoclonal (180.2)
  • western blot; human; fig 2e
Santa Cruz Biotechnology CDC6 antibody (Santa, sc-9964) was used in western blot on human samples (fig 2e). Cell Rep (2014) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:1000; fig 2
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, sc-9964) was used in western blot on human samples at 1:1000 (fig 2). J Cell Sci (2014) ncbi
mouse monoclonal (180.2)
  • western blot; human
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, 180.2) was used in western blot on human samples . J Biol Chem (2013) ncbi
mouse monoclonal (180.2)
  • western blot; human; 1:1000
Santa Cruz Biotechnology CDC6 antibody (Santa Cruz, sc-9964) was used in western blot on human samples at 1:1000. Nucleic Acids Res (2011) ncbi
Abcam
domestic rabbit monoclonal (EPR759Y)
  • western blot; human; loading ...; fig 2a, 2b
Abcam CDC6 antibody (Abcam, ab75809) was used in western blot on human samples (fig 2a, 2b). Cell Rep (2017) ncbi
domestic rabbit monoclonal (EPR761(2))
  • immunohistochemistry; brown rat; 1:1000
Abcam CDC6 antibody (Abcam, ab76422) was used in immunohistochemistry on brown rat samples at 1:1000. Front Synaptic Neurosci (2014) ncbi
Proteintech Group
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Proteintech Group CDC6 antibody (ProteinTech Group, 11640-1-AP) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
Invitrogen
mouse monoclonal (DCS-180)
  • western blot; mouse; fig 1
In order to investigate regulatory mechanisms that control homologous recombination, Invitrogen CDC6 antibody (Invitrogen, DCS180) was used in western blot on mouse samples (fig 1). Stem Cell Res (2012) ncbi
MilliporeSigma
mouse monoclonal (DCS-180)
  • western blot; human; loading ...; fig 1c
MilliporeSigma CDC6 antibody (Sigma-Aldrich, C0224) was used in western blot on human samples (fig 1c). Nat Commun (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C42F7)
  • western blot; human; loading ...; fig 1c, 1d
Cell Signaling Technology CDC6 antibody (Cell Signaling, 3387) was used in western blot on human samples (fig 1c, 1d). Cell Rep (2017) ncbi
domestic rabbit monoclonal (C42F7)
  • western blot; human; loading ...; fig 1g
In order to demonstrate a role for CDC6 in cell survival and DNA replication, Cell Signaling Technology CDC6 antibody (Cell Signaling, 3387) was used in western blot on human samples (fig 1g). elife (2016) ncbi
domestic rabbit monoclonal (C42F7)
  • western blot; human; 1:1000
In order to study the role of YAP in cell proliferation and survival using different cell types, Cell Signaling Technology CDC6 antibody (Cell Signaling, 3387) was used in western blot on human samples at 1:1000. PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C42F7)
  • western blot; human
Cell Signaling Technology CDC6 antibody (Cell Signaling, 3387) was used in western blot on human samples . J Biol Chem (2013) ncbi
Articles Reviewed
  1. Coulombe P, Nassar J, Peiffer I, Stanojcic S, Sterkers Y, Delamarre A, et al. The ORC ubiquitin ligase OBI1 promotes DNA replication origin firing. Nat Commun. 2019;10:2426 pubmed publisher
  2. Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed publisher
  3. Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
  4. Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, et al. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017;18:1970-1981 pubmed publisher
  5. Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
  6. Yang H, Zhao X, Zhao L, Liu L, Li J, Jia W, et al. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma. Oncotarget. 2016;7:72131-72147 pubmed publisher
  7. Urbán N, van den Berg D, Forget A, Andersen J, Demmers J, Hunt C, et al. Return to quiescence of mouse neural stem cells by degradation of a proactivation protein. Science. 2016;353:292-5 pubmed publisher
  8. Huang Y, Amin A, Qin Y, Wang Z, Jiang H, Liang L, et al. A Role of hIPI3 in DNA Replication Licensing in Human Cells. PLoS ONE. 2016;11:e0151803 pubmed publisher
  9. Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher
  10. Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  11. Greil C, Krohs J, Schnerch D, Follo M, Felthaus J, Engelhardt M, et al. The role of APC/C(Cdh1) in replication stress and origin of genomic instability. Oncogene. 2016;35:3062-70 pubmed publisher
  12. Yao M, Xie C, Kiang M, Teng Y, Harman D, Tiffen J, et al. Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells. Oncotarget. 2015;6:34458-74 pubmed publisher
  13. Cardona M, López J, Serafín A, Rongvaux A, Inserte J, García Dorado D, et al. Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart. PLoS ONE. 2015;10:e0131411 pubmed publisher
  14. Shen Z, Stanger B. YAP regulates S-phase entry in endothelial cells. PLoS ONE. 2015;10:e0117522 pubmed publisher
  15. Wu M, Lu W, Santos R, Frattini M, Kelly T. Geminin inhibits a late step in the formation of human pre-replicative complexes. J Biol Chem. 2014;289:30810-21 pubmed publisher
  16. Fernandez Vidal A, Guitton Sert L, Cadoret J, Drac M, Schwob E, Baldacci G, et al. A role for DNA polymerase ? in the timing of DNA replication. Nat Commun. 2014;5:4285 pubmed publisher
  17. Betts J, Schweimer J, Burnham K, Burnet P, Sharp T, Harrison P. D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine. Front Synaptic Neurosci. 2014;6:11 pubmed publisher
  18. Wang J, Xu X, Alontaga A, Chen Y, Liu Y. Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction. Cell Rep. 2014;7:848-58 pubmed publisher
  19. Clijsters L, Wolthuis R. PIP-box-mediated degradation prohibits re-accumulation of Cdc6 during S phase. J Cell Sci. 2014;127:1336-45 pubmed publisher
  20. Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher
  21. Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem. 2013;288:17532-43 pubmed publisher
  22. Tichy E, Pillai R, Deng L, Tischfield J, Hexley P, Babcock G, et al. The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem Cell Res. 2012;9:124-34 pubmed publisher
  23. Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed publisher