This is a Validated Antibody Database (VAD) review about human CCR2, based on 27 published articles (read how Labome selects the articles), using CCR2 antibody in all methods. It is aimed to help Labome visitors find the most suited CCR2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CCR2 synonym: CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R

BioLegend
mouse monoclonal (K036C2)
  • flow cytometry; human; loading ...
BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples . J Exp Med (2022) ncbi
mouse monoclonal (K036C2)
  • mass cytometry; human; 1:100; loading ...; fig s2
BioLegend CCR2 antibody (Biolegend, K036C2) was used in mass cytometry on human samples at 1:100 (fig s2). Int J Mol Sci (2021) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; fig 3a
BioLegend CCR2 antibody (Biolegend, 357205) was used in flow cytometry on human samples (fig 3a). Sci Rep (2021) ncbi
mouse monoclonal (K036C2)
  • mass cytometry; human; loading ...; fig 4e
BioLegend CCR2 antibody (Biolegend, K036C2) was used in mass cytometry on human samples (fig 4e). Acta Neuropathol (2021) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; loading ...; fig 2e
BioLegend CCR2 antibody (BioLegend, 357214) was used in flow cytometry on human samples (fig 2e). Cell (2020) ncbi
mouse monoclonal (K036C2)
  • immunohistochemistry; human; loading ...; fig 2c
BioLegend CCR2 antibody (Biolegend, K036C2) was used in immunohistochemistry on human samples (fig 2c). Bone Rep (2020) ncbi
mouse monoclonal (K036C2)
  • mass cytometry; human; loading ...; fig 2j
BioLegend CCR2 antibody (Biolegend, 357202) was used in mass cytometry on human samples (fig 2j). Cell (2019) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; 1:100; loading ...; fig 3s1
BioLegend CCR2 antibody (Biolegend, 357207) was used in flow cytometry on human samples at 1:100 (fig 3s1). elife (2019) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; 1:100; loading ...; fig 1h, s5g
BioLegend CCR2 antibody (Biolegend, 357212) was used in flow cytometry on human samples at 1:100 (fig 1h, s5g). Cancer Cell (2019) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; fig 4c
BioLegend CCR2 antibody (BioLegend, 357206) was used in flow cytometry on human samples (fig 4c). J Exp Med (2018) ncbi
mouse monoclonal (K036C2)
  • mass cytometry; human; loading ...; fig s3b
In order to map the lineage of human dendritic cells, BioLegend CCR2 antibody (BioLegend, KO36C2) was used in mass cytometry on human samples (fig s3b). Science (2017) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; loading ...; fig 4d
In order to characterize gammadelta T cell subsets from healthy humans, BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples (fig 4d). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; loading ...; tbl 1
In order to demonstrate that freezing already-stained samples suspended in 10% DMSO in FBS is practical and efficient way to preserve already-stained samples for mass cytometry assessment, BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples (tbl 1). Cytometry A (2017) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; fig 5
BioLegend CCR2 antibody (Biolegend, 357203) was used in flow cytometry on human samples (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; fig 3
In order to investigate the dynamics and characteristics of natural killer cell types in the human ocular mucosal surface in situ during infection with group D human adenoviruses, BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples (fig 3). Mucosal Immunol (2016) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human
BioLegend CCR2 antibody (Biolegend, K036C2) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (K036C2)
  • flow cytometry; human; fig 6
In order to investigate the impact of CCR6(+)CXCR3(+)CCR4(-) cells in latent tuberculosis infection, BioLegend CCR2 antibody (BioLegend, K036C2) was used in flow cytometry on human samples (fig 6). J Immunol (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR19698)
  • flow cytometry; human; loading ...; fig 7g
Abcam CCR2 antibody (Abcam, ab203128) was used in flow cytometry on human samples (fig 7g). Clin Transl Med (2022) ncbi
mouse monoclonal (7A7)
  • immunohistochemistry - paraffin section; human; loading ...; fig 4a
Abcam CCR2 antibody (Abcam, 7A7) was used in immunohistochemistry - paraffin section on human samples (fig 4a). Int J Mol Sci (2021) ncbi
mouse monoclonal (7A7)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig s8a
Abcam CCR2 antibody (Abcam, ab176390) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s8a). Theranostics (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:50; loading ...; fig s3c
Invitrogen CCR2 antibody (Thermo scientific, PA5-23037) was used in immunohistochemistry on mouse samples at 1:50 (fig s3c). Sci Rep (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-11)
  • immunocytochemistry; human; fig 6d
Santa Cruz Biotechnology CCR2 antibody (Santa Cruz, SC-74490) was used in immunocytochemistry on human samples (fig 6d). Toxins (Basel) (2017) ncbi
Novus Biologicals
domestic rabbit polyclonal
Novus Biologicals CCR2 antibody (Novus, NBP1-48338) was used . Nature (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D14H7)
  • western blot; human; fig 7f
Cell Signaling Technology CCR2 antibody (Cell Signaling Technology, 12199S) was used in western blot on human samples (fig 7f). Clin Transl Med (2022) ncbi
BD Biosciences
mouse monoclonal (48607)
  • flow cytometry; human; loading ...; fig 1d
BD Biosciences CCR2 antibody (BD Biosciences, 561744) was used in flow cytometry on human samples (fig 1d). PLoS ONE (2016) ncbi
mouse monoclonal (48607)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences CCR2 antibody (BD, 558406) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (48607)
  • flow cytometry; human; fig 3
BD Biosciences CCR2 antibody (BD Biosciences, 48 607) was used in flow cytometry on human samples (fig 3). Nephrol Dial Transplant (2015) ncbi
Articles Reviewed
  1. Amaral E, Foreman T, Namasivayam S, Hilligan K, Kauffman K, Barbosa Bomfim C, et al. GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection. J Exp Med. 2022;219: pubmed publisher
  2. Zhu Y, Gu H, Yang L, Li N, Chen Q, Kang D, et al. Involvement of MST1/mTORC1/STAT1 activity in the regulation of B-cell receptor signalling by chemokine receptor 2. Clin Transl Med. 2022;12:e887 pubmed publisher
  3. Popovic Z, Bestvater F, Krunic D, Krämer B, Bergner R, Löffler C, et al. CD73 Overexpression in Podocytes: A Novel Marker of Podocyte Injury in Human Kidney Disease. Int J Mol Sci. 2021;22: pubmed publisher
  4. West J, Austin E, Rizzi E, Yan L, Tanjore H, Crabtree A, et al. KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models. Int J Mol Sci. 2021;22: pubmed publisher
  5. Fang W, Sofia Acevedo D, Smart C, Zinda B, Alissa N, Warren K, et al. Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression. Sci Rep. 2021;11:8708 pubmed publisher
  6. Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed publisher
  7. Chu C, Lee Y, Hsieh C, Yeh C, Chao T, Chen P, et al. Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy. Theranostics. 2021;11:3624-3641 pubmed publisher
  8. Pasciuto E, Burton O, Roca C, Lagou V, Rajan W, Theys T, et al. Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. Cell. 2020;182:625-640.e24 pubmed publisher
  9. Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed publisher
  10. Zhang Z, Le K, La Placa D, Armstrong B, Miller M, Shively J. CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils. Bone Rep. 2020;12:100237 pubmed publisher
  11. Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
  12. Gonzalo Gil E, Rapuano P, Ikediobi U, Leibowitz R, Mehta S, Coskun A, et al. Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members. elife. 2019;8: pubmed publisher
  13. Cassetta L, Fragkogianni S, Sims A, Swierczak A, Forrester L, Zhang H, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. 2019;35:588-602.e10 pubmed publisher
  14. Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed publisher
  15. Gillman A, Breshears L, Kistler C, Finnegan P, Torres V, Schlievert P, et al. Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel). 2017;9: pubmed publisher
  16. See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  17. Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
  18. Ryan P, Sumaria N, Holland C, Bradford C, Izotova N, Grandjean C, et al. Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals. Proc Natl Acad Sci U S A. 2016;113:14378-14383 pubmed
  19. Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed publisher
  20. Pinilla Vera M, Xiong Z, Zhao Y, Zhao J, Donahoe M, Barge S, et al. Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. PLoS ONE. 2016;11:e0159329 pubmed publisher
  21. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  22. Zhang L, Zhang S, Yao J, Lowery F, Zhang Q, Huang W, et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature. 2015;527:100-104 pubmed publisher
  23. McCausland M, Juchnowski S, Zidar D, Kuritzkes D, Andrade A, Sieg S, et al. Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy. PLoS ONE. 2015;10:e0139474 pubmed publisher
  24. Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed publisher
  25. Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed publisher
  26. Rogacev K, Zawada A, Hundsdorfer J, Achenbach M, Held G, Fliser D, et al. Immunosuppression and monocyte subsets. Nephrol Dial Transplant. 2015;30:143-53 pubmed publisher
  27. Arlehamn C, Seumois G, Gerasimova A, Huang C, Fu Z, Yue X, et al. Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features. J Immunol. 2014;193:2931-40 pubmed publisher