This is a Validated Antibody Database (VAD) review about human CCNA1, based on 38 published articles (read how Labome selects the articles), using CCNA1 antibody in all methods. It is aimed to help Labome visitors find the most suited CCNA1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CCNA1 synonym: CT146

Knockout validation
Cell Signaling Technology
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 5b
  • western blot knockout validation; mouse; loading ...; fig 3b
In order to look for potential tumor suppressors and examine their function as cell cycle modulators and investigate their impact on the cyclin family of proteins and cyclin dependent kinases, Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples (fig 5b) and in western blot knockout validation on mouse samples (fig 3b). Mol Pharmacol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-3)
  • western blot; mouse; loading ...; fig 2g
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz Biotechnology, sc-271,645) was used in western blot on mouse samples (fig 2g). BMC Cancer (2020) ncbi
mouse monoclonal (H-3)
  • western blot; human; loading ...; fig 3c
Santa Cruz Biotechnology CCNA1 antibody (Santa, sc-271645) was used in western blot on human samples (fig 3c). Cell Cycle (2020) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz Biotechnology, B-8) was used in western blot on human samples (fig 2a). Sci Adv (2019) ncbi
mouse monoclonal (B-8)
  • immunocytochemistry; human; 1:100; loading ...; fig 4a
Santa Cruz Biotechnology CCNA1 antibody (Santa, sc271682) was used in immunocytochemistry on human samples at 1:100 (fig 4a). elife (2019) ncbi
mouse monoclonal (XLA1-1)
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology CCNA1 antibody (Santa, sc-53233) was used in western blot on human samples (fig 2c). Clin Cancer Res (2018) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 6
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz Biotechnology Inc., sc-271682) was used in western blot on human samples (fig 6). Drug Des Devel Ther (2016) ncbi
mouse monoclonal (H-3)
  • western blot; human; fig 2
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz, sc-271645) was used in western blot on human samples (fig 2). BMC Cancer (2016) ncbi
mouse monoclonal (B-8)
  • immunocytochemistry; human; 1:100; fig 1
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz Biotechnology, sc-271682) was used in immunocytochemistry on human samples at 1:100 (fig 1). Cell Cycle (2016) ncbi
mouse monoclonal (B-8)
  • western blot; human; fig 3
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz, sc-271682) was used in western blot on human samples (fig 3). Cell Div (2015) ncbi
mouse monoclonal (H-3)
  • western blot; human
Santa Cruz Biotechnology CCNA1 antibody (Santa Cruz, sc-271645) was used in western blot on human samples . Exp Cell Res (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a, 5b
Abcam CCNA1 antibody (Abcam, ab53699) was used in western blot on human samples at 1:1000 (fig 5a, 5b). Biol Proced Online (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s12f
Abcam CCNA1 antibody (Abcam, ab133183) was used in western blot on mouse samples at 1:1000 (fig s12f). Science (2016) ncbi
Cell Signaling Technology
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples (fig 2c). Mol Ther Oncolytics (2022) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, 4656) was used in western blot on human samples at 1:1000 (fig 3b). Clin Transl Med (2021) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, 4656) was used in western blot on human samples (fig 5e). Oncogene (2021) ncbi
mouse monoclonal (BF683)
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology CCNA1 antibody (Cell Signaling, BF683) was used in western blot on mouse samples (fig 4b). PLoS ONE (2020) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:2000; loading ...; fig 5a
Cell Signaling Technology CCNA1 antibody (CST, 4656) was used in western blot on human samples at 1:2000 (fig 5a). Int J Mol Med (2020) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000; loading ...; fig 6c
Cell Signaling Technology CCNA1 antibody (CST, 4656) was used in western blot on human samples at 1:1000 (fig 6c). Genes Cancer (2019) ncbi
mouse monoclonal (BF683)
  • western blot; mouse; loading ...; fig s4b
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on mouse samples (fig s4b). Gastroenterology (2018) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples (fig 2c). J Biol Chem (2017) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig s3b
Cell Signaling Technology CCNA1 antibody (Cell signaling, 4656) was used in western blot on human samples (fig s3b). Nat Commun (2017) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 5b
  • western blot knockout validation; mouse; loading ...; fig 3b
In order to look for potential tumor suppressors and examine their function as cell cycle modulators and investigate their impact on the cyclin family of proteins and cyclin dependent kinases, Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples (fig 5b) and in western blot knockout validation on mouse samples (fig 3b). Mol Pharmacol (2017) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000; fig 3C
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples at 1:1000 (fig 3C). PLoS ONE (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000; fig 5c
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, 4656) was used in western blot on human samples at 1:1000 (fig 5c). Cancer Chemother Pharmacol (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 5c
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, 4656) was used in western blot on human samples (fig 5c). FEBS Open Bio (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; fig 5
Cell Signaling Technology CCNA1 antibody (Cell signaling, 4656) was used in western blot on human samples (fig 5). J Biol Chem (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; loading ...; fig 5b
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples (fig 5b). PLoS ONE (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples at 1:1000 (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:2000; fig 4
In order to assess antiproliferative inhibitors of protein-protein interactions by pooled screening, Cell Signaling Technology CCNA1 antibody (Cell Signaling, BF683) was used in western blot on human samples at 1:2000 (fig 4). Nat Chem Biol (2016) ncbi
mouse monoclonal (BF683)
  • immunohistochemistry - paraffin section; human; fig 1a
Cell Signaling Technology CCNA1 antibody (Cell Signaling, BF683) was used in immunohistochemistry - paraffin section on human samples (fig 1a). BMC Cancer (2015) ncbi
mouse monoclonal (BF683)
  • immunoprecipitation; human; fig 5
  • western blot; human; fig 5
In order to report that inappropriate activation of CDK2 in S phase affects checkpoint kinase 1 inhibitor sensitivity in a subset of cell lines, Cell Signaling Technology CCNA1 antibody (Cell Signaling Tech, cst-4656) was used in immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig 5). Oncotarget (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; fig 5
In order to characterize modulation of microtubular structure and HSP90alpha chaperone activity against prostate cancer by 4-hydroxybenzoic acid derivatives as HDAC6-specific inhibitors, Cell Signaling Technology CCNA1 antibody (Cell signaling, 4656S) was used in western blot on human samples (fig 5). Biochem Pharmacol (2016) ncbi
mouse monoclonal (BF683)
  • western blot; human; fig 1
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, 4656) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
mouse monoclonal (BF683)
  • western blot; human
In order to study CREB in acute myeloid leukemia, Cell Signaling Technology CCNA1 antibody (Cell Signaling, BF683) was used in western blot on human samples . Leukemia (2015) ncbi
mouse monoclonal (BF683)
  • western blot; human
Cell Signaling Technology CCNA1 antibody (Cell Signaling, BF683) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
mouse monoclonal (BF683)
  • western blot; human; 1:1000
In order to determine if NaAsO2 and hyperthermia alter cisplatin-induced G2 arrest and cause mitotic arrest and mitotic catastrophe, Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656) was used in western blot on human samples at 1:1000. Toxicol Sci (2014) ncbi
mouse monoclonal (BF683)
  • western blot; mouse; 1:1000
Cell Signaling Technology CCNA1 antibody (Cell Signaling, 4656S) was used in western blot on mouse samples at 1:1000. PLoS ONE (2013) ncbi
mouse monoclonal (BF683)
  • western blot; human; fig 4
Cell Signaling Technology CCNA1 antibody (Cell Signaling Technology, BF683) was used in western blot on human samples (fig 4). Biochem J (2013) ncbi
Articles Reviewed
  1. Fei X, Wu X, Dou Y, Sun K, Guo Q, Zhang L, et al. TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I. Mol Ther Oncolytics. 2022;26:413-428 pubmed publisher
  2. Deng Y, Li Y, Wu T, Chen X, Li X, Cai K, et al. RAD6 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma by Regulating Histone Ubiquitination of CCNB1. Biol Proced Online. 2022;24:4 pubmed publisher
  3. Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher
  4. Fischietti M, Eckerdt F, Blyth G, Arslan A, Mati W, Oku C, et al. Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma. Oncogene. 2021;40:3273-3286 pubmed publisher
  5. Chen A, Santana A, Doudican N, Roudiani N, Laursen K, Therrien J, et al. MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation. PLoS ONE. 2020;15:e0241551 pubmed publisher
  6. Kuo I, Lee J, Wang Y, Chiang H, Huang C, Hsieh P, et al. Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia. BMC Cancer. 2020;20:603 pubmed publisher
  7. Mlyczynska E, Kurowska P, Drwal E, Opydo Chanek M, Tworzydło W, Kotula Balak M, et al. Apelin and apelin receptor in human placenta: Expression, signalling pathway and regulation of trophoblast JEG‑3 and BeWo cells proliferation and cell cycle. Int J Mol Med. 2020;45:691-702 pubmed publisher
  8. Singh V, Khalil M, De Benedetti A. The TLK1/Nek1 axis contributes to mitochondrial integrity and apoptosis prevention via phosphorylation of VDAC1. Cell Cycle. 2020;19:363-375 pubmed publisher
  9. Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed publisher
  10. Yoshida A, Bu Y, Qie S, Wrangle J, Camp E, Hazard E, et al. SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors. Sci Adv. 2019;5:eaax6352 pubmed publisher
  11. Bigot N, Day M, Baldock R, Watts F, Oliver A, Pearl L. Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. elife. 2019;8: pubmed publisher
  12. He P, Yang J, Yang V, Bialkowska A. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018;154:1494-1508.e13 pubmed publisher
  13. Zhao Z, Jia Q, Wu M, Xie X, Wang Y, Song G, et al. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018;24:130-144 pubmed publisher
  14. Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
  15. Cayrol F, Praditsuktavorn P, Fernando T, Kwiatkowski N, Marullo R, Calvo Vidal M, et al. THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors. Nat Commun. 2017;8:14290 pubmed publisher
  16. Choiniere J, Wu J, Wang L. Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. Mol Pharmacol. 2017;91:189-196 pubmed publisher
  17. Lv M, Li Y, Tian X, Dai S, Sun J, Jin G, et al. Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis. Drug Des Devel Ther. 2016;10:3737-3746 pubmed
  18. Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
  19. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  20. Kang M, Park K, Yang J, Lee C, Oh S, Yun J, et al. miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells. PLoS ONE. 2016;11:e0160961 pubmed publisher
  21. Fiedor E, Gregoraszczuk E. The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. Cancer Chemother Pharmacol. 2016;78:611-22 pubmed publisher
  22. Qi J, Li T, Bian H, Li F, Ju Y, Gao S, et al. SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis. FEBS Open Bio. 2016;6:326-37 pubmed publisher
  23. Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  24. Park S, Lee J, Herbst R, Koo J. GSK-3? Is a Novel Target of CREB and CREB-GSK-3? Signaling Participates in Cell Viability in Lung Cancer. PLoS ONE. 2016;11:e0153075 pubmed publisher
  25. Jung Y, Decker A, Wang J, Lee E, Kana L, Yumoto K, et al. Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow. Oncotarget. 2016;7:25698-711 pubmed publisher
  26. Nim S, Jeon J, Corbi Verge C, Seo M, Ivarsson Y, Moffat J, et al. Pooled screening for antiproliferative inhibitors of protein-protein interactions. Nat Chem Biol. 2016;12:275-81 pubmed publisher
  27. Kuo C, Li X, Stark J, Shih H, Ann D. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016;15:787-98 pubmed publisher
  28. Lee E, Jin D, Lee B, Kim Y, Han J, Shim Y, et al. Negative effect of cyclin D1 overexpression on recurrence-free survival in stage II-IIIA lung adenocarcinoma and its expression modulation by vorinostat in vitro. BMC Cancer. 2015;15:982 pubmed publisher
  29. Sakurikar N, Thompson R, Montano R, Eastman A. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase. Oncotarget. 2016;7:1380-94 pubmed publisher
  30. Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed publisher
  31. Borges K, Arboleda V, Vilain E. Mutations in the PCNA-binding site of CDKN1C inhibit cell proliferation by impairing the entry into S phase. Cell Div. 2015;10:2 pubmed publisher
  32. Su C, Zhang C, Tecle A, Fu X, He J, Song J, et al. Tudor staphylococcal nuclease (Tudor-SN), a novel regulator facilitating G1/S phase transition, acting as a co-activator of E2F-1 in cell cycle regulation. J Biol Chem. 2015;290:7208-20 pubmed publisher
  33. Chae H, Mitton B, Lacayo N, Sakamoto K. Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. Leukemia. 2015;29:1379-89 pubmed publisher
  34. Zhang H, Zhang D, Zha Z, Hu C. Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells. Biochim Biophys Acta. 2014;1839:1330-40 pubmed publisher
  35. Machado Neto J, Lazarini M, Favaro P, Franchi G, Nowill A, Saad S, et al. ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells. Exp Cell Res. 2014;324:137-45 pubmed publisher
  36. Muenyi C, Trivedi A, Helm C, States J. Cisplatin plus sodium arsenite and hyperthermia induces pseudo-G1 associated apoptotic cell death in ovarian cancer cells. Toxicol Sci. 2014;139:74-82 pubmed publisher
  37. Baldo B, Soylu R, Petersen A. Maintenance of basal levels of autophagy in Huntington's disease mouse models displaying metabolic dysfunction. PLoS ONE. 2013;8:e83050 pubmed publisher
  38. Andrews P, He Z, Tzenov Y, Popadiuk C, Kao K. Evidence of a novel role for Pygopus in rRNA transcription. Biochem J. 2013;453:61-70 pubmed publisher