This is a Validated Antibody Database (VAD) review about human CCL3, based on 5 published articles (read how Labome selects the articles), using CCL3 antibody in all methods. It is aimed to help Labome visitors find the most suited CCL3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CCL3 synonym: G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3; C-C motif chemokine 3; G0/G1 switch regulatory protein 19-1; PAT 464.1; SIS-beta; chemokine (C-C motif) ligand 3; macrophage inflammatory protein 1-alpha; small inducible cytokine A3 (homologous to mouse Mip-1a); tonsillar lymphocyte LD78 alpha protein

R&D Systems
mouse monoclonal (93321)
  • other; human; fig s1
In order to investigate the mechanisms of toxicity by the negative allosteric modulators of metabotropic glutamate receptor 5, R&D Systems CCL3 antibody (R&D Systems, MAB270) was used in other on human samples (fig s1). Cell Chem Biol (2017) ncbi
goat polyclonal
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2c
In order to explore the role of hippocampal T cell infiltration in tau-driven pathophysiology and cognitive impairments, R&D Systems CCL3 antibody (R&D, AF-450-NA) was used in immunohistochemistry on mouse samples at 1:100 (fig 2c). Brain (2017) ncbi
mouse monoclonal (93342)
  • flow cytometry; human; 4:100; fig 3a
In order to show that hepatitis B virus exposure in utero enhances immunity to bacterial infections, R&D Systems CCL3 antibody (R&D Systems, 93342) was used in flow cytometry on human samples at 4:100 (fig 3a). Nat Commun (2015) ncbi
goat polyclonal
  • ELISA; human; fig 6
R&D Systems CCL3 antibody (R&D systems, AB-270-NA) was used in ELISA on human samples (fig 6). Eur J Immunol (2015) ncbi
Invitrogen
mouse monoclonal (14D7 1G7)
  • dot blot; human; tbl s1
In order to use polydimethylsiloxane microchambers to co-detect 42 immune effector proteins secreted from a single LPS-stimulation macrophage, Invitrogen CCL3 antibody (Invitrogen, AHC6034) was used in dot blot on human samples (tbl s1). Proc Natl Acad Sci U S A (2015) ncbi
Articles Reviewed
  1. Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
  2. Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
  3. Hong M, Sandalova E, Low D, Gehring A, Fieni S, Amadei B, et al. Trained immunity in newborn infants of HBV-infected mothers. Nat Commun. 2015;6:6588 pubmed publisher
  4. Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed publisher
  5. Gouwy M, De Buck M, Pörtner N, Opdenakker G, Proost P, Struyf S, et al. Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines. Eur J Immunol. 2015;45:101-12 pubmed publisher