This is a Validated Antibody Database (VAD) review about human CBX3, based on 14 published articles (read how Labome selects the articles), using CBX3 antibody in all methods. It is aimed to help Labome visitors find the most suited CBX3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CBX3 synonym: HECH; HP1-GAMMA; HP1Hs-gamma

Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s6e
Abcam CBX3 antibody (Abcam, ab10480) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s6e). EMBO J (2022) ncbi
domestic rabbit monoclonal
  • immunocytochemistry; human; loading ...; fig 3e
  • western blot; human; loading ...; fig 3h
Abcam CBX3 antibody (Abcam, ab217999) was used in immunocytochemistry on human samples (fig 3e) and in western blot on human samples (fig 3h). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s7b
Abcam CBX3 antibody (Abcam, ab10480) was used in western blot on human samples (fig s7b). Cancer Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5g
In order to describe a role for NIPBL in DNA damage repair, Abcam CBX3 antibody (Abcam, ab10480) was used in western blot on human samples at 1:1000 (fig 5g). J Cell Sci (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Abcam CBX3 antibody (abcam, ab10480) was used in western blot on mouse samples (fig 5). Oncotarget (2016) ncbi
Active Motif
mouse monoclonal (2MOD-1G6)
  • immunocytochemistry; mouse; fig 10
Active Motif CBX3 antibody (Active motif, 39981) was used in immunocytochemistry on mouse samples (fig 10). elife (2016) ncbi
mouse monoclonal (2MOD-1G6)
  • immunohistochemistry - paraffin section; human; loading ...; fig 3d
Active Motif CBX3 antibody (Active Motif, 39981) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Nucleic Acids Res (2015) ncbi
mouse monoclonal (2MOD-1G6)
  • chromatin immunoprecipitation; human
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:1000
Active Motif CBX3 antibody (Active Motif, 39981) was used in chromatin immunoprecipitation on human samples , in immunocytochemistry on human samples at 1:200 and in western blot on human samples at 1:1000. Mol Cell Biol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; loading ...; fig s3b
Santa Cruz Biotechnology CBX3 antibody (Santa Cruz Biotechnology, sc-398562) was used in western blot on human samples (fig s3b). Cell Death Dis (2019) ncbi
mouse monoclonal (E-7)
  • chromatin immunoprecipitation; human; fig 7
In order to study how nuclear corepressor 1 contributes to cancer, Santa Cruz Biotechnology CBX3 antibody (Santa Cruz, sc-365085) was used in chromatin immunoprecipitation on human samples (fig 7). Proc Natl Acad Sci U S A (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4a
Cell Signaling Technology CBX3 antibody (Cell Signaling Technology, 2600) was used in immunohistochemistry on mouse samples at 1:50 (fig 4a). J Clin Invest (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 3a
Cell Signaling Technology CBX3 antibody (Cell Signaling, 2619) was used in western blot on mouse samples (fig 3a). Cell Signal (2018) ncbi
domestic rabbit polyclonal
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; fig s3
Cell Signaling Technology CBX3 antibody (Cell Signaling, 2600S) was used in RNA immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig s3). Genome Biol (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:400; fig 3b
  • western blot; human; 1:1000; fig 3a
Cell Signaling Technology CBX3 antibody (Cell Signaling Technology, 2619) was used in immunocytochemistry on human samples at 1:400 (fig 3b) and in western blot on human samples at 1:1000 (fig 3a). Oncotarget (2016) ncbi
Articles Reviewed
  1. Jiang Z, Li H, Schroer S, Voisin V, Ju Y, Pacal M, et al. Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes. EMBO J. 2022;41:e106825 pubmed publisher
  2. Cai H, Yu Y, Ni X, Li C, Hu Y, Wang J, et al. LncRNA LINC00998 inhibits the malignant glioma phenotype via the CBX3-mediated c-Met/Akt/mTOR axis. Cell Death Dis. 2020;11:1032 pubmed publisher
  3. Alajati A, D Ambrosio M, Troiani M, Mosole S, Pellegrini L, Chen J, et al. CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo. J Clin Invest. 2020;130:2435-2450 pubmed publisher
  4. Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher
  5. Wu Y, Li X, Yu J, Bjorkholm M, Xu D. ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells. Cell Death Dis. 2019;10:76 pubmed publisher
  6. Lee C, Hsieh T. Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts. Cell Signal. 2018;47:16-26 pubmed publisher
  7. Bot C, Pfeiffer A, Giordano F, Manjeera D, Dantuma N, Ström L. Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage. J Cell Sci. 2017;130:1134-1146 pubmed publisher
  8. Sobecki M, Mrouj K, Camasses A, Parisis N, Nicolas E, Llères D, et al. The cell proliferation antigen Ki-67 organises heterochromatin. elife. 2016;5:e13722 pubmed publisher
  9. G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  10. Chung S, Moon H, Ju H, Kim D, Cho K, Ribback S, et al. Comparison of liver oncogenic potential among human RAS isoforms. Oncotarget. 2016;7:7354-66 pubmed publisher
  11. Martínez Iglesias O, Alonso Merino E, Gómez Rey S, Velasco Martín J, Martín Orozco R, Luengo E, et al. Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2016;113:E328-37 pubmed publisher
  12. Huang R, Langdon S, Tse M, Mullen P, Um I, Faratian D, et al. The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer. Oncotarget. 2016;7:4695-711 pubmed publisher
  13. Mishima Y, Jayasinghe C, Lu K, Otani J, Shirakawa M, Kawakami T, et al. Nucleosome compaction facilitates HP1γ binding to methylated H3K9. Nucleic Acids Res. 2015;43:10200-12 pubmed publisher
  14. Boros J, Arnoult N, Stroobant V, Collet J, Decottignies A. Polycomb repressive complex 2 and H3K27me3 cooperate with H3K9 methylation to maintain heterochromatin protein 1? at chromatin. Mol Cell Biol. 2014;34:3662-74 pubmed publisher